Navigation Links
Bayer and Onyx Initiate Phase 3 Trial of Nexavar in Non-Small Cell Lung Cancer
Date:6/1/2009

WAYNE, N.J. and EMERYVILLE, Calif., June 1 /PRNewswire-FirstCall/ -- Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that the companies have begun enrolling patients in an international Phase 3 trial to evaluate Nexavar(R) (sorafenib) tablets in patients with non-squamous non-small cell lung cancer (NSCLC) who have failed two or three previous treatments.

"Nexavar has proven efficacy in liver cancer and kidney cancer and we are committed to researching Nexavar in a variety of other solid tumors," said Dimitris Voliotis, MD, vice president, Nexavar Clinical Development, Bayer HealthCare Pharmaceuticals. "Based on the results of a signal generating Phase 2 study, Bayer and Onyx initiated this Phase 3 trial to evaluate Nexavar in non-small cell lung cancer."

Phase 3 Trial Design

The MISSION (Monotherapy admInistration of Sorafenib in patientS wIth nOn-small cell luNg cancer) trial, is an international multicenter study that will enroll approximately 850 patients with advanced relapsed or refractory non-squamous NSCLC who have failed two or three previous treatments. Patients will be randomized to receive either Nexavar as single agent or placebo. In both treatment arms, best supportive care will be provided. The primary endpoint of this trial is overall survival, and secondary endpoints include progression-free survival and overall response rate. The safety and tolerability of the two treatment groups will also be compared.

The study will be conducted at more than 120 sites in North America, South America, Europe, Africa and the Asia-Pacific region, including Japan. For information about this study, please visit www.clinicaltrials.gov.


'/>"/>
SOURCE Bayer HealthCare Pharmaceuticals, Inc.; Onyx Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. IVCC launches groundbreaking insecticide projects with Bayer and Syngenta
2. AUDIO from Medialink and Bayer: Simple, Focused Ways to Boost Womens Health
3. Bayer HealthCare Cleared to Acquire Citracal(R)
4. Genzyme and Bayer Schering Pharma AG, Germany to Present New Data on Alemtuzumab in Multiple Sclerosis at ECTRIMS
5. Bayer Foundation Grant Creates Graduate Engineering Fellowship at University of Houston
6. AUDIO from Medialink and Bayer: Is Your Pain Reliever Undermining Your Aspirin Therapy?
7. Bayer Temporarily Suspends Global Trasylol(R) Marketing
8. AUDIO from Medialink and Bayer: Lifesaving Benefits of Low-Dose Aspirin Therapy Maintained with Naproxen Sodium
9. Bayer Plants Trees With Chartiers Valley Intermediate School Students, Provides Free Environmental Education Materials
10. Bayer Awards Making Science Make Sense Grant to Girl Scouts
11. Bayer HealthCare Pharmaceuticals and MedAssets Supply Chain Systems Sign a Three-Year Agreement for Magnevist(R) Magnetic Resonance Contrast Media
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/3/2015)... SC (PRWEB) , ... July ... ... has announced the sessions and speaker lineup for its 2015 Annual ... taking place August 6-8, 2015 at the Renaissance Orlando at SeaWorld in ...
(Date:7/3/2015)... ... 2015 , ... Renowned rhinoplasty surgeon and Symposium Chairman, Dr. ... Symposium . To be held from March 4th - 6th, the 2016 (a previous ... Galleria Dallas. , Designed to take participants from the basic training and fundamentals of ...
(Date:7/3/2015)... ... July 03, 2015 , ... ... providers, has been retained to lead a national chief nursing officer recruitment ... executive search firms in the healthcare industry, B. E. Smith has recently placed ...
(Date:7/3/2015)... ... July 03, 2015 , ... Smoothies are all the ... good blender and easily accessible, quality ingredients. Aurora Natural is proud to introduce a ... added boost of fiber, protein, antioxidants, vitamins and minerals! , Aurora is offering a ...
(Date:7/3/2015)... ... July 03, 2015 , ... Jennifer Renee Hanes, DO is the new ... the largest network of independent freestanding emergency rooms in the United States. , “We ... Sienna Plantation facility,” said Executive Medical Director of First Choice Emergency Room, Dr. James ...
Breaking Medicine News(10 mins):Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 2Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 3Health News:Dr. Rod J. Rohrich Announces the Dates for 2016 Dallas Rhinoplasty Symposium 2Health News:Dr. Rod J. Rohrich Announces the Dates for 2016 Dallas Rhinoplasty Symposium 3Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 2Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 3Health News:Aurora Product, Inc. Announces An Original New Line: Smoothie Fixins’ 2Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 2Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 3
... South Beach’s Premier Med Spa ... Spa Concierge to the Me Day Spa Family. , ... (PRWEB) April 13, 2010 -- Spring Break on South Beach never ends and the ... as Miami’s premier med spa celebrates one theme: Revive. Refresh. Renew., , ,For one week, Me ...
... but only if they didn,t smoke, study found , TUESDAY, ... drinking, you,ve probably heard that it might reduce your risk ... supports that notion, but it also finds that light drinking,s ... , "Any potential beneficial effect of drinking moderate amounts of ...
... ... Otology and Neurotology a “Letter to the Editor” documenting the improvement for memory loss ... focuses on two recent cases that were referred to Dr. Lippy, following stapedectomy surgery ... ...
... ... Proton’s T-4, the newest and currently most powerful degausser on the ... a “Best of FOSE 2010” award at the FOSE conference in Washington, ... for quick and automatic sanitization of magnetic media such as hard drives ...
... ... in MTV’s ‘Jersey Shore’ was a Bullfrog Spa. , ... Salt Lake City, Utah (Vocus) April 13, 2010 -- Ever wonder ... understandably reluctant to point it out, Bullfrog International is ready to admit that it is ...
... salads, nuts, tomatoes and poultry lowered the odds, researchers say ... high in vegetables, fish, fruit, nuts and poultry, and low ... Alzheimer,s disease, new research finds. , Researchers asked more than ... their dietary habits. Over the course of about four years, ...
Cached Medicine News:Health News:Me Day Spa Celebrates Spa Week Specials + New Client Concierge on South Beach 2Health News:Smoking May Erase Heart Benefits of Light Drinking 2Health News:Smoking May Erase Heart Benefits of Light Drinking 3Health News:New Study Identifies Cause of Severe Disequilibrium and Significant Memory Loss Following Stapedectomy Surgery 2Health News:Proton's T-4 Automatic Degausser Receives “Best of FOSE 2010” Award 2Health News:Proton's T-4 Automatic Degausser Receives “Best of FOSE 2010” Award 3Health News:The Identity of the Jersey Shore Hot Tub Revealed 2Health News:Healthy Diet Could Cut Alzheimer's Disease Risk 2Health News:Healthy Diet Could Cut Alzheimer's Disease Risk 3
(Date:7/2/2015)... July 2, 2015  The Commission for Certification ... ASHP, an organization that represents pharmacists in acute ... of continuing education for recertification of Certified Geriatric ... geriatric programs for this purpose.  ASHP will join ... providers for the CCGP Professional Development Program. ...
(Date:7/2/2015)... South Korea, July 2, 2015 ALPINION MEDICAL SYSTEMS ... E-CUBE Series ultrasound system. Developed to enhance user experience ... the E-CUBE 15 EX produces superb image quality. With ... in women,s health, general imaging, and shared service applications. ... latest in the renowned E-CUBE Series, the E-CUBE 15 ...
(Date:7/2/2015)... 2015 Research and Markets( ... "Veterinary / Animal Vaccines Market by Product, Diseases & ... their offering. The global animal vaccines market ... $5,507.3 Million in 2015, at a CAGR of 5.5% ... market growth are growing prevalence of animal diseases, increasing ...
Breaking Medicine Technology:Commission for Certification in Geriatric Pharmacy Adds ASHP as Professional Development Program Provider 2E-CUBE 15 EX from ALPINION Enhances User Experience and Patient Care 2E-CUBE 15 EX from ALPINION Enhances User Experience and Patient Care 3Veterinary / Animal Vaccines Market 2015 - Global Forecast to 2020 for the $7.19 Billion Industry 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: