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Bayer and Onyx Announce Nexavar Data Presentations at the Joint 15th European CanCer Organisation (ECCO) and 34th European Society for Medical Oncology (ESMO) Multidisciplinary Congress
Date:9/15/2009

  • Dirk Jager, M.D., National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany
  • Abstract 7128, Poster 141, Monday, September 21, 2009, 2 p.m. - 5 p.m., Hall 14.1
  • Breast Cancer

    • A double-blind, randomized phase 2b study evaluating the efficacy and safety of sorafenib (SOR) compared to placebo (PL) when administered in combination with capecitabine (CAP) in patients (pts) with locally advanced (adv) or metastatic (met) breast cancer (BC)
      • Jose Baselga, M.D., Vall d'Hebron University Hospital in Barcelona, Spain
      • Late-breaking abstract 3LBA, Presidential Session III, Wednesday, September 23, 1:30 p.m., Hall 1

    Thyroid Cancer

    • Completion of a Phase II study of sorafenib for advanced thyroid cancer
      • Marcia Brose, M.D., Ph.D. Department of Medicine, Division of Hematology/Oncology and Department of Otorhinolaryngology: Head and Neck Surgery, Abrahamson Cancer Center of the University of Pennsylvania, Philadelphia, PA, U.S.A.
      • Late-breaking poster 51LBA, Poster 276, Tuesday, September 22, 11 a.m. - 1:00 p.m. Hall 14.1

    Nexavar's Differentiated Mechanism

    Nexavar targets both the tumor cell and tumor vasculature. In preclinical studies, Nexavar has been shown to target members of two classes of kinases known to be involved in both cell proliferation (growth) and angiogenesis (blood supply) - two important processes that enable cancer growth. These kinases included Raf kinase, VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-B, KIT, FLT-3 and RET.

    Nexavar is currently approved in more than 80 countries for the treatment of patients with liver cancer and in more than 9
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    SOURCE Onyx Pharmaceuticals, Inc.; Bayer HealthCare Pharmaceuticals Inc.
    Copyright©2009 PR Newswire.
    All rights reserved

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