Navigation Links
Battling Bacteria in the Blood: U-M Researchers Tackle Deadly Infections
Date:11/11/2008

bacterial infection, while mice that didn't receive the drug were able to clear the infection from their bloodstream. The model successfully showed the same outcome.

An important part of bloodstream infections associated with catheters is the clumping-together of bacteria on surfaces - which is also seen in urinary catheters that cause many thousands of infections each year. But clumping that occurs within the bloodstream itself is also important since it may help bacteria become more vulnerable to immune system response.

The paper in the Bulletin of Mathematical Biology describes a model of this process - known as flocculation - and sets the stage for further study of treatments that might accelerate clumping or make the clumps more stable. That, in turn, might help the body fight off infection more effectively.

Younger and his team have more research to do before their models yield results that might affect human treatment. But already, they are seeing the potential for how to improve the models and use them to simulate different aspects of human bacteremia and sepsis.

"We're trying to understand the rules for how bacteria traffic in the bloodstream - and if you understand the timing of those events you might be able to better understand how best to detect the bloodstream infection when it's present," he says. "We're also working on ways to fundamentally change the rules of engagement between the bacteria and the host. There are mechanical features at play in terms of getting these bacteria in flowing blood out. If we can change the mechanics of that interaction, then we can potentially have a therapy that the bacteria don't really have an opportunity to defend against or develop resistance against. And that could be a useful therapy."

The research is funded by the National Institutes of Health and the U-M Center for Computational Medicine and Biology.


'/>"/>
SOURCE University of Michigan Health System
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Teleflora and Nationally Recognized Hospitals to Honor Women Battling Breast Cancer
2. Battling bird flu by the numbers
3. Government and Corporate Support Together Help Africans Battling Malaria, AIDS
4. The SCOOTER Store Donates Power Scooter to an Uninsured Young Father Battling Cancer
5. Healing Starts With Us National Campaign Commits to Battling Depression - By Any Means Necessary
6. Einstein researchers genetically engineer immune cells into potent weapons for battling HIV
7. Battling potential disease outbreaks online
8. Math battling cancer, deciding lifes challenges lead list as INFORMS meet in Seattle
9. Six Olympic Legends Battling Chronic Diseases Lead Revolution in Advancing Pharmacy Care as Medco Launches the Tour of Champions
10. Antibiotics Not Always Best Bet for Battling Childhood Ear Infections
11. Parental Involvement Key to Battling Bulimia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2015)... (PRWEB) May 22, 2015 Omar Ahmad ... selected to participate in the 2015 Congress of Future ... described as a gathering of “America’s highest achieving high ... areas of healthcare, set new goals and learn better ... a live surgery, during which we can ask the ...
(Date:5/22/2015)... 22, 2015 Hands On HealthCare Massage ... 2015, the Annual One Day Sale on Massage ... On HCMT offers drastically reduced certificates one day a year. ... enough sessions, through what used to be the slowest time ... the community as well. This once a year occurrence has ...
(Date:5/22/2015)... DC (PRWEB) May 22, 2015 Family, ... University Hospital’s world-renowned surgical oncologist, Dr. LaSalle D. Leffall, ... , The luncheon began after Grand Rounds in the ... Leffall, waited anxiously outside the auditorium, trying to keep ... him, but if he sees me, he’ll know something ...
(Date:5/22/2015)... 2015 Coordinating care for people ... Historically providers have not been reimbursed or rewarded ... 2015, Medicare has paved the way by offering ... the launch of Oculus Health , an ... using the platform will now be able to ...
(Date:5/22/2015)... Seattle, WA (PRWEB) May 22, 2015 According ... adults of all generations are equally as likely to worry ... (72% Millennials, 75% Gen X, 77% Boomers, 69% Silent Generation), ... (45%) agree they are scared of aging, particularly Millennials (47%), ... online by Harris Poll in April, 2015 among more than ...
Breaking Medicine News(10 mins):Health News:Milton Hershey School Student Chosen for Congress of Future Medical Leaders 2Health News:Hands On HealthCare Massage Therapy & Wellness Day Spa Announces Their Eighth Annual One Day Sale on Gift Certificates Will Take Place on June 17, 2015 2Health News:Hands On HealthCare Massage Therapy & Wellness Day Spa Announces Their Eighth Annual One Day Sale on Gift Certificates Will Take Place on June 17, 2015 3Health News:Colleagues Surprise Dr. LaSalle Leffall with 85th Birthday Celebration 2Health News:Oculus Health Care Coordination Platform Officially Launched 2Health News:Oculus Health Care Coordination Platform Officially Launched 3Health News:Oculus Health Care Coordination Platform Officially Launched 4Health News:New Study Reveals America’s Fear of Aging 2Health News:New Study Reveals America’s Fear of Aging 3
... Out of Pocket Expenses ... for Medical Foods, ... BMRN) announced today that it has,provided a $250,000 grant to the ... program for patients with,phenylketonuria (PKU), a rare genetic metabolic disorder. Funds ...
... CME LLC (http://www.CMELLC.com ), a,leading provider of ... announced it has been granted five-year full approval ... sponsor of,continuing medical education for APA members. ... part of the APA,s,Continuing Education in Psychology (CEP) ...
... SUNNYVALE, Calif., October 24, 2007 The Parkinsons Institute ... nicotine treatment reduces medication-induced dyskinesias by as much as ... by senior research scientist, Maryka Quik, Ph.D., the research ... Annals of Neurology. , Levodopa, the most ...
... (Nasdaq: ANSV ) will announce financial results for ... November 1, 2007 and will hold a,webcast teleconference at ... will discuss financial results from the third quarter 2007,as ... pipeline, recent,events and milestones. Interested parties can listen ...
... drives ... administrative expense ratio continues to improve, declining ... shares of its common stock during the ... quarter for $2.4 billion, INDIANAPOLIS, Oct. 24 WellPoint, Inc. (NYSE:,WLP) today announced ...
... BEIJING, Oct. 24 /Xinhua-PRNewswire-FirstCall/ -- China Medical,Technologies, Inc. (the "Company") (Nasdaq: CMED ... diagnostic products and high intensity focused ultrasound tumor,therapy systems, today announced the following ... ... Location ...
Cached Medicine News:Health News:BioMarin Provides Grant to NORD to Expand PKU Patient Support Services 2Health News:BioMarin Provides Grant to NORD to Expand PKU Patient Support Services 3Health News:BioMarin Provides Grant to NORD to Expand PKU Patient Support Services 4Health News:BioMarin Provides Grant to NORD to Expand PKU Patient Support Services 5Health News:CME LLC Granted Five-Year Full Approval by the American Psychological Association 2Health News:Parkinson's Institute research shows that nicotine reduces levodopa-induced dyskinesias 2Health News:Anesiva to Announce Third Quarter 2007 Financial Results and Host Webcast Conference Call on November 1, 2007 2Health News:WellPoint Reports Third Quarter 2007 Results 2Health News:WellPoint Reports Third Quarter 2007 Results 3Health News:WellPoint Reports Third Quarter 2007 Results 4Health News:WellPoint Reports Third Quarter 2007 Results 5Health News:WellPoint Reports Third Quarter 2007 Results 6Health News:WellPoint Reports Third Quarter 2007 Results 7Health News:WellPoint Reports Third Quarter 2007 Results 8Health News:WellPoint Reports Third Quarter 2007 Results 9Health News:WellPoint Reports Third Quarter 2007 Results 10Health News:WellPoint Reports Third Quarter 2007 Results 11Health News:WellPoint Reports Third Quarter 2007 Results 12Health News:WellPoint Reports Third Quarter 2007 Results 13Health News:WellPoint Reports Third Quarter 2007 Results 14Health News:WellPoint Reports Third Quarter 2007 Results 15Health News:WellPoint Reports Third Quarter 2007 Results 16Health News:WellPoint Reports Third Quarter 2007 Results 17Health News:WellPoint Reports Third Quarter 2007 Results 18Health News:WellPoint Reports Third Quarter 2007 Results 19Health News:WellPoint Reports Third Quarter 2007 Results 20Health News:WellPoint Reports Third Quarter 2007 Results 21Health News:WellPoint Reports Third Quarter 2007 Results 22Health News:WellPoint Reports Third Quarter 2007 Results 23Health News:WellPoint Reports Third Quarter 2007 Results 24Health News:China Medical Technologies to Participate in Investor Events in November 2
(Date:5/22/2015)... May 22, 2015 Electrophysiologist Kevin Makati, ... traveled to Boston, MA ... 2015 Heart Rhythm Society conference. These scientific sessions ... on the ideas, people and technology that propel ... a hybrid, minimally invasive cardiac operation that combines ...
(Date:5/22/2015)... 22, 2015  The U.S. Food and Drug ... the first biosimilar product approved in ... growth in the contract manufacturing organization (CMO) industry, ... is geared to the production of small-molecular drugs ... products. The healthcare market research publisher,s report, ...
(Date:5/22/2015)... According to a new market ... Instruments, Services), by Test Type (Indirect, Enzyme-based, Reactive Oxygen ... End Users - Global Forecast to 2020", published by ... reach $736.85 Million by 2020 from $452.36 Million in ... Browse 71 market data Tables and 90 Figures ...
Breaking Medicine Technology:St. Joseph's Hospital Heart Institute Physician Presents at Heart Rhythm Society 2St. Joseph's Hospital Heart Institute Physician Presents at Heart Rhythm Society 3Kalorama: First FDA-Approved Biosimilar Brings Hope for CMO Growth 2Kalorama: First FDA-Approved Biosimilar Brings Hope for CMO Growth 3Kalorama: First FDA-Approved Biosimilar Brings Hope for CMO Growth 4Oxidative Stress Assays Market Worth $736.85 Million by 2020 2Oxidative Stress Assays Market Worth $736.85 Million by 2020 3Oxidative Stress Assays Market Worth $736.85 Million by 2020 4
... 25, 2011 Nano Mask, Inc. (NMI) (Pink Sheets: ... distribution company focused on emergency and critical care as ... has entered into a distribution agreement with a Saudi ... line on an exclusive basis to: The Kingdom of ...
... Food and Drug Administration today approved Firazyr (icatibant) Injection for ... hereditary angioedema (HAE) in people ages 18 years and older. ... ) HAE is caused ... called C1 inhibitor, which is involved in regulating how certain ...
Cached Medicine Technology:Nano Mask Enters Into Four-Year Distribution Agreement With Saudi Medical Products Distributor 2FDA Approves Firazyr To Treat Acute Attacks of Hereditary Angioedema 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: