Navigation Links
Bat Saliva-Based Stroke Drug Disappoints in Trial
Date:12/18/2008

But the study's design may be to blame for desmoteplase's poor showing, researchers say

THURSDAY, Dec. 18 (HealthDay News) -- An experimental clot-busting drug derived from the saliva of the vampire bat has failed to reduce stroke damage in a major trial.

But hope for the drug, called desmoteplase, remains alive, experts say, because the study may not have been large enough to provide clear results.

"The sample size was underpowered to detect any benefit," said study co-author Dr. Anthony J. Furlan, chairman of neurology at Case Western Reserve University, in Cleveland. "The simplest answer is that stroke is an extremely heterogeneous condition, and it is difficult to predict what the outcomes will be from a smaller size population."

Two earlier and smaller studies showed a benefit when desmoteplase was given intravenously to reopen brain arteries blocked by clots. But there was no significant difference in outcome in the latest trial, called DIAS-2, between stroke victims given desmoteplase and those who got a placebo, said a report to be published online on Dec. 17 in The Lancet Neurology.

But there remains vigorous debate about the best method to use in selecting those stroke patients who will be treated in the next trial, which is in the planning stage, Furlan added.

Desmoteplase was originally spotted in the saliva of the vampire bat, which uses the chemical to keep its victims' blood flowing freely, so it can suck a full meal.

The drug is contending to replace tissue plasminogen activator (tPA), the only current treatment for ischemic strokes, which are caused by blockage of a blood vessel. Most strokes are ischemic strokes; tPA is given by intravenous injection and works quickly to dissolve clots.

"But tPA must be given within three hours of a stroke, so only a small percentage of patients can get the treatment," Furlan noted. "We hope to triple that window to
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Study, meta-analysis examine factors associated with death from heatstroke
2. High alcohol consumption increases stroke risk among Chinese men
3. Heavy Drinking Boosts Stroke Risk for Chinese Men
4. High alcohol consumption increases stroke risk, Tulane study says
5. Broad-based group of physicians calls for improvement in stroke treatment
6. Continued Statin Use Boosts Post-Stroke Outcomes
7. U.S. Initiative Seeks to Boost Hispanic Stroke Awareness
8. Stopping Statins After Stroke Doubles Death Risk
9. Can brain-injured, partially-blind stroke patients regain some of their lost vision?
10. REACH Registry Highlights That Patients With Peripheral Arterial Disease (PAD) Suffer High Rates of Heart Attack, Stroke, Hospitalization, and Death
11. Link Between Air Pollution, Stroke Gets Clearer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Bat Saliva-Based Stroke Drug Disappoints in Trial
(Date:6/2/2015)... Health Management, LLC, a provider of outcome data, aftercare ... announced today that Jared Smith has joined the company ... responsible for developing and implementing a marketing strategy to ... products and initiatives. , Prior to joining MAP, Mr. ... Irving, Texas, where he was responsible for developing and ...
(Date:6/2/2015)... (PRWEB) June 02, 2015 ... the opening of Surrey’s first fertility clinic. ... boasts a diverse, young community, with one ... http://www.theglobeandmail.com/news/british-columbia/four-reasons-bcs-fastest-growing-city-is-a-political-powerhouse/article21408253/ , Until now patients from ... had to come into Vancouver or Burnaby ...
(Date:6/2/2015)... Though almost the entire Park family was born ... rule their lives. Organizing and hosting the June 14 event ... to the fullest and spreading awareness of HHT. , “I've ... won't live my life in a bubble because something bad ... is to look back on your life with regret because ...
(Date:6/2/2015)... 2015 CRN International has been named a ... Employment , a Connecticut state program that takes active steps ... them at appropriate companies. , Platform to Employment is being ... Connecticut Department of Labor. CRN, a 40-year-old radio marketing company ... is being recognized for its “hard work and dedication.” , ...
(Date:6/2/2015)... NC (PRWEB) June 02, 2015 ... training and compliance solutions for the healthcare market, ... The Arc to offer 10 complimentary courses relating ... provide public safety professionals with additional resources to ... Safety professionals are often the first responders to ...
Breaking Medicine News(10 mins):Health News:Jared Smith Joins MAP Health Management, LLC, as Vice President of Marketing 2Health News:Olive Fertility Centre Opens First Fertility Clinic in Surrey BC 2Health News:Family brings awareness to genetic disease at first Memphis walk 2Health News:CRN Named Company Partner of the Year by CT Employment Program 2Health News:Relias Learning Partners with Behavioral Health and Developmental Disabilities Leaders to Offer Complimentary Resources to Public Safety Professionals 2Health News:Relias Learning Partners with Behavioral Health and Developmental Disabilities Leaders to Offer Complimentary Resources to Public Safety Professionals 3
... biological and genetics-based explanation for the causes of anorexia ... for their illness than those given a sociocultural explanation, ... found. , This is a potentially important finding, said ... wider dissemination of information about the biological and genetic ...
... /Xinhua-PRNewswire/ -- Sundia MediTech,(Shanghai) Company recently announced a welcome ... Zhu and Dr. Shu Gao. Dr. Zhu is appointed ... as the Vice,President in charge of Chemical Synthesis business., ... his college,education in chemistry in Nanjing University in China. ...
... PPD, Inc. (Nasdaq:,PPDI) will release its fourth quarter and ... the market closes. The earnings,release will be available on ... PR Newswire., On Thursday, February 7, 2008, at ... and audio webcast to discuss financial results and the,overall ...
... HIV Rates; Governor Should Cut,Bureaucracy, Corporate Loopholes, ... today urged California Governor Arnold Schwarzenegger to,reconsider and ... AIDS services,that will reduce and threaten vital lifesaving ... he seeks to close a $14 billion,deficit in ...
... Commends CMS for Setting Date but Fear that Program ... Jan. 10 The Power Mobility,Coalition (PMC) today applauded ... a date certain when all Medicare DMEPOS,suppliers need to ... to two years for the requirement to be fully ...
... antiviral drugs fail , , THURSDAY, Jan. 10 (HealthDay News) ... that help HIV propagate, creating hope for new treatments ... a technique called RNA interference to screen thousands of ... the study published online Jan. 10 in Science ...
Cached Medicine News:Health News:People with anorexia less likely to be blamed when biology, genetics explained 2Health News:People with anorexia less likely to be blamed when biology, genetics explained 3Health News:CRO Company Sundia Welcomes New Members to Its Executive Team 2Health News:PPD Announces Fourth Quarter and Year-End 2007 Earnings Release, Webcast and Conference Call 2Health News:AHF to Schwarzenegger: 'AIDS Cuts Are Deadly' 2Health News:AHF to Schwarzenegger: 'AIDS Cuts Are Deadly' 3Health News:Mandatory Accreditation Delayed Until September 2009 2Health News:New Proteins That Help HIV Grow Identified 2
(Date:6/2/2015)... , June 2, 2015  ErgoNurse, the leader in bedside ... healthcare products in the United States , ... home, long-term care and skilled nursing markets. ... Thousands ... to fully take advantage of the ErgoNurse products to stop ...
(Date:6/2/2015)... , June 2, 2015  Integrated Service Solutions, Inc. ("the Company") announced today they are expanding their reach nationally by ... ... ... ... ...
(Date:6/2/2015)... Today AmerisourceBergen, a global healthcare solutions leader, ... Olive Branch, MS ; ... . The facilities will operate within AmerisourceBergen,s existing ... increase supply chain efficiency and enhance patient care. ... ongoing investments, more than $1 billion over the last ...
Breaking Medicine Technology:ErgoNurse and Briggs Healthcare Positioned to Completely Eliminate the Unnecessary Cost of Healthcare-Related Back Injuries 2Integrated Service Solutions, Inc. Announces Nationwide Expansion for On-site Pipette Calibrations 2Integrated Service Solutions, Inc. Announces Nationwide Expansion for On-site Pipette Calibrations 3Integrated Service Solutions, Inc. Announces Nationwide Expansion for On-site Pipette Calibrations 4AmerisourceBergen to Build Three New Distribution Centers 2
... 14, 2011 LifeVantage Corporation (OTCBB: LFVN), the ... revenue for its third fiscal quarter of 2011 of approximately ... or 35% over net revenue of $7.4 million for the ... an approximate $7.3 million or 270% increase in net revenue ...
... CITY, Iowa, April 14, 2011 Ron Van ... Natural Science , announced that research conducted at Iowa ... in DiaGel eliminates bacteria on contact. ... microdilution testing, disk diffusion, and traditional microbiological plating.  Through ...
Cached Medicine Technology:LifeVantage Announces Preliminary Third Quarter 2011 Revenue 2Van Beek Natural Science's Patented Active Compound in DiaGel Offers one Dose Natural Cure for Pet Bacterial Diarrhea 2
The interface spatula can be used when irregular interface adherence occurs. By beginning at the point of a dissected edge and sweeping in uniplanar motion towards the area of adherence, the flap can...
Duckbilled spatula designed to enter a side-port stab incision with tip broad enough to efficiently manipulate the lens nucleus in the anterior chamber. Spatula is useful for rotating and cracking th...
Ideal for bimanual phaco procedure. 0.25 mm by 10 mm long blade. Round knurled handle with polished finish....
1 mm wide by 28 mm long sterling silver blade. Flat serrated handle with polished finish....
Medicine Products: