Navigation Links
Basis created for directing and filming blood vessels
Date:3/26/2008

A new method of filming blood-vessel cells that move in accordance with targeted signals has been developed by researchers at Uppsala University in collaboration with researchers at the University of California. The method can also be used to study how migration of cancer cells and nerves can be controlled. These interesting findings have now been published in the Journal of Biological Chemistry.

Formation of new blood cells and lymph vessels takes place with a number of different diseases. Formation of new cells is sometimes desirable, e.g. in the event of wound healing, when new tissue must be formed. Undesirable vessel formation takes place in the event of tumour growth. The tumour receives nutrition from the new blood vessels and can also spread via newly formed lymph vessels, thus prevention of vessel growth is desirable in this situation.

A major challenge in the field of medicine is understanding the signals governing the way vessels are formed. It has been proposed that targeted signals so-called gradients from growth factors instruct the vessels as to the direction in which they are to grow.

"Our study shows that a simple gradient from a signal protein is sufficient to tell the blood vessel cell in which direction it is to move. We have also been able to show that the form of the gradient governs the way in which the cell moves," says Irmeli Barkefors, a postgraduate student at Uppsala University.

The research group is now going to develop the method further. The aim is to be able to study targeted migration in complicated organ culture systems, whereby interaction between different cell types can be studied.

"The method can basically be adapted to facilitate study of all types of cells. It is particularly important to study the mechanisms that determine whether or not cancer cells spread," says researchers Johan Kreuger, who has been heading the project.


'/>"/>

Contact: Dr. Johan Kreuger
johan.kreuger@imbim.uu.se
46-073-394-9094
Uppsala University
Source:Eurekalert

Page: 1

Related medicine news :

1. Ranbaxy Receives Tentative Approval to Manufacture and Market Galantamine Tablets on an Exclusive Basis
2. APHA Urges President Bush to Reconsider Unfounded Basis for SCHIP Veto
3. The structural basis of familial hypertrophic cardiomyopathy is revealed
4. American Association for Homecare Disputes Validity of Internet Power Wheelchair Prices as Basis for Reimbursement of Services in Medicare
5. HSA Plans are Covering Preventive Care on a First-Dollar Basis
6. New book presents comprehensive survey of research into the molecular basis of aging
7. Twins study shows genetic basis for face and place recognition
8. MITs McGovern Institute researchers awarded $8.5M to study brain basis of autism and dyslexia
9. KV Pharmaceutical Reports Record Revenues for Fiscal 2008 Third Quarter and Year-to-Date on a Preliminary Basis
10. Not all risk is created equal
11. New Case Study Details How an Illinois Hospital Created a Safe Lifting Team that Dramatically Reduced Injuries, Increased Staff Satisfaction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2017)... ... 2017 , ... Patients who avoid necessary dental and endodontic treatments because of ... NY from Advanced Endodontics of Westchester. This highly-trained team of endodontists offer three different ... sedation methods may be recommended based on the severity of the anxiety experienced by ...
(Date:5/22/2017)... ... May 22, 2017 , ... Today, Our Urgent Care celebrates the grand opening ... ribbon cutting ceremony. Since opening over a month ago, Our Urgent Care Washington ... The new Our Urgent Care walk-in clinic is located at 3195 Phoenix Center ...
(Date:5/22/2017)... ... May 22, 2017 , ... “Homeostasis: The Journey of ... to live with Bipolar 1. Donald Rodriguez takes readers on a rollercoaster ride that ... the dead of winter and to a dark place where Donald considers suicide. ...
(Date:5/22/2017)... ... May 22, 2017 , ... Faithfully following pop culture, ... squatted, stretched, jumped, toned and shaped through fitness programs. It carries on to skin ... finished off with an irresistible, radiant smile. CDA has found that just ...
(Date:5/22/2017)... ... May 22, 2017 , ... OSF Ventures, the corporate ... InsightRX, an early stage company in San Francisco that has developed software to ... Ventures Innovation Fund acted as the lead investor in the round. , ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... Inc. (Nasdaq: HOLX ) announced today the ... April 1, 2017 .   GAAP diluted earnings per ... prior year period as the sale of the blood ... diluted EPS of $0.50 increased 6.4%.  Revenue of $715.4 ... Excluding the effects of blood screening and the acquired ...
(Date:5/10/2017)... 10, 2017  The Corporate Whistleblower Center says, ... sleep therapy clinics to call us anytime at ... is involved in a substantial scheme to overbill ... from an employee of a medical equipment company ... to provide medical practice groups with extra generous incentives ...
(Date:5/10/2017)... CSSi, the global leader in patient recruitment, ... is proud to announce the launch of its newly ... both enriched content and a customized layout that provides ... already well-established position as the top global patient recruitment ... months of hard work, we are delighted to officially ...
Breaking Medicine Technology: