Navigation Links
Basis created for directing and filming blood vessels
Date:3/26/2008

A new method of filming blood-vessel cells that move in accordance with targeted signals has been developed by researchers at Uppsala University in collaboration with researchers at the University of California. The method can also be used to study how migration of cancer cells and nerves can be controlled. These interesting findings have now been published in the Journal of Biological Chemistry.

Formation of new blood cells and lymph vessels takes place with a number of different diseases. Formation of new cells is sometimes desirable, e.g. in the event of wound healing, when new tissue must be formed. Undesirable vessel formation takes place in the event of tumour growth. The tumour receives nutrition from the new blood vessels and can also spread via newly formed lymph vessels, thus prevention of vessel growth is desirable in this situation.

A major challenge in the field of medicine is understanding the signals governing the way vessels are formed. It has been proposed that targeted signals so-called gradients from growth factors instruct the vessels as to the direction in which they are to grow.

"Our study shows that a simple gradient from a signal protein is sufficient to tell the blood vessel cell in which direction it is to move. We have also been able to show that the form of the gradient governs the way in which the cell moves," says Irmeli Barkefors, a postgraduate student at Uppsala University.

The research group is now going to develop the method further. The aim is to be able to study targeted migration in complicated organ culture systems, whereby interaction between different cell types can be studied.

"The method can basically be adapted to facilitate study of all types of cells. It is particularly important to study the mechanisms that determine whether or not cancer cells spread," says researchers Johan Kreuger, who has been heading the project.


'/>"/>

Contact: Dr. Johan Kreuger
johan.kreuger@imbim.uu.se
46-073-394-9094
Uppsala University
Source:Eurekalert

Page: 1

Related medicine news :

1. Ranbaxy Receives Tentative Approval to Manufacture and Market Galantamine Tablets on an Exclusive Basis
2. APHA Urges President Bush to Reconsider Unfounded Basis for SCHIP Veto
3. The structural basis of familial hypertrophic cardiomyopathy is revealed
4. American Association for Homecare Disputes Validity of Internet Power Wheelchair Prices as Basis for Reimbursement of Services in Medicare
5. HSA Plans are Covering Preventive Care on a First-Dollar Basis
6. New book presents comprehensive survey of research into the molecular basis of aging
7. Twins study shows genetic basis for face and place recognition
8. MITs McGovern Institute researchers awarded $8.5M to study brain basis of autism and dyslexia
9. KV Pharmaceutical Reports Record Revenues for Fiscal 2008 Third Quarter and Year-to-Date on a Preliminary Basis
10. Not all risk is created equal
11. New Case Study Details How an Illinois Hospital Created a Safe Lifting Team that Dramatically Reduced Injuries, Increased Staff Satisfaction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... MA (PRWEB) October 22, 2014 ... new solutions for the treatment of bacterial infections, microbial ... Sinskey has joined its board of directors. , ... and Engineering Systems at The Massachusetts Institute of Technology, ... MIT faculty since 1968. Dr. Sinskey also holds positions ...
(Date:10/22/2014)... By Tara Haelle ... -- Binge drinking among young adult men may lead to ... binge drinking didn,t cause a similar rise in blood pressure ... study. In fact, when young adult women drank lightly or ... half, the study found. "This finding parallels studies in ...
(Date:10/22/2014)... By Dennis Thompson HealthDay ... freelance cameraman who was diagnosed with Ebola while working for ... system and can leave the special isolation unit at Nebraska Medical ... two weeks, the hospital said Tuesday. A blood test confirmed ... Ashoka Mukpo, 33, can head home to Providence, R.I., NBC ...
(Date:10/20/2014)... October 20, 2014 The Advocator ... booth at the American Foundation for Suicide Prevention’s (AFSP) ... AFSP is a not-for-profit organization that hosts hundreds of ... from these events are used to help understand and ... and personal relationships as well. , The Advocator ...
(Date:10/20/2014)... 2014 hc1.com today announced the ... solution that enables healthcare organizations of all sizes ... customer relationship management (“CRM”) solution. , Designed from ... of the healthcare industry, the hc1 Healthcare Relationship ... patients by combining healthcare CRM, HIPAA-compliant collaboration, and ...
Breaking Medicine News(10 mins):Health News:Akeso Biomedical Appoints Dr. Anthony J. Sinskey to Board of Directors 2Health News:Binge Drinking May Boost Blood Pressure in Young Men 2Health News:Binge Drinking May Boost Blood Pressure in Young Men 3Health News:Binge Drinking May Boost Blood Pressure in Young Men 4Health News:U.S. Cameraman Treated for Ebola 'Free' of the Virus 2Health News:U.S. Cameraman Treated for Ebola 'Free' of the Virus 3Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 2Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 3Health News:Healthcare Relationship Management (HRM) Leader hc1.com® Launches hc1® Quick Start™ 2
... of brain diseases caused by mutant prion proteins, such as ... if normal prion proteins can be depleted, researchers report. ... cow disease called variant Creutzfeldt-Jakob disease, is thought to be ... this causes normal prion protein to follow suit. The accumulation ...
... design, Duke University Medical Center researchers have created// a ... of physicians to repair damaged joints with the patient's ... are successful, the scaffold could be used in clinical ... a graduate student in the Orthopedic Bioengineering Laboratory who ...
... proteins in amniotic fluid that signal a higher risk ... by Yale School of Medicine researchers who presented their ... Medicine Conference February 8 in San Francisco. ... with abnormal proteomic profiles (MR scores) are more likely ...
... Rattled by an increase in fratricidal killings, the paramilitary and ... that affects troops posted in inhospitable terrain and in insurgency ... and paramilitary personnel were trained here recently in a six-day ... special sessions among their colleagues. ,"In order ...
... that fluctuations in Vitamin D3 levels control the body’s ... heal. ,Richard L. Gallo, M.D., Ph.D., professor ... and the Dermatology section of the Veterans Affairs San ... fluctuations of the body’s vitamin D3 and infectious disease ...
... spread awareness of health issues like stroke// , prostate ... be as vital as any doctor, drug or diagnostic test. ... at the American Stroke Association's International Stroke Conference suggests beauty ... about strokes. ,In the study, researchers gave lessons ...
Cached Medicine News:Health News:Woven Cartilage 2Health News:Prematurity More Accurately Predicted by Advances in Proteomic Technology 2Health News:Soldiers Readying to Fight Stress With Yoga 2Health News:Vitamin D3 Protects Skin from Harmful Microbes 2Health News:Beauticians and Barbers can Do More Than Their Services 2
(Date:10/22/2014)... Oct. 22, 2014  Paper Pak Industries, a ... APLS ® Body Guard Bio, a disposable, ... of bacteria and virus while protecting service providers ... Bio features a rugged, external nylon shell, watertight ... a leak-proof inner chamber that contains contaminated and ...
(Date:10/22/2014)... Inc. (NYSE: CRY ), a leading medical ... vascular surgery, announced today that James Patrick (Pat) ... elected to the Company,s Board of Directors, effective October ... Executive Chairman of CryoLife, stated, "Since joining the Company in ... who is well positioned to maximize CryoLife,s potential.  His ...
(Date:10/22/2014)... Oct. 21, 2014   BioNano Genomics , ... genomics research centers to purchase an Irys™ System ... National Cancer Institute (NCI), NIH Intramural Sequencing Center (NISC) ... Irys, obtaining a comprehensive view of a genome ... (NGS) does not deliver the scalability or reliability ...
Breaking Medicine Technology:New, State-Of-The-Art Body Bag Minimizes The Spread Of Bacteria And Virus 2Pat Mackin Joins CryoLife Board of Directors 2Pat Mackin Joins CryoLife Board of Directors 3BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 2BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 3
... Clinical Care Options (CCO), a leader in next-generation ... today announced the addition of the ClinicalTrials.gov database ... CME resource for specialists in HIV and oncology. ... own continuously updated comprehensive textbook, features a sophisticated ...
... Oct. 5, 2011 NxStage® Medical, Inc. (Nasdaq: ... dialysis products and together with its patients and their ... of their passion and enthusiasm, NxStageUsers, together with thousands ... NxStage by helping to change the dialysis treatment paradigm ...
Cached Medicine Technology:Clinical Care Options Announces Addition of ClinicalTrials.gov Database to CCO inPractice™ Point-of-Care Resource 2Clinical Care Options Announces Addition of ClinicalTrials.gov Database to CCO inPractice™ Point-of-Care Resource 3NxStage Says 'Thank You' to Patients and Care Partners at the 2nd Annual NxStageUsers Meet-Up and Conference in New Orleans 2NxStage Says 'Thank You' to Patients and Care Partners at the 2nd Annual NxStageUsers Meet-Up and Conference in New Orleans 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: