Navigation Links
Basis created for directing and filming blood vessels
Date:3/26/2008

A new method of filming blood-vessel cells that move in accordance with targeted signals has been developed by researchers at Uppsala University in collaboration with researchers at the University of California. The method can also be used to study how migration of cancer cells and nerves can be controlled. These interesting findings have now been published in the Journal of Biological Chemistry.

Formation of new blood cells and lymph vessels takes place with a number of different diseases. Formation of new cells is sometimes desirable, e.g. in the event of wound healing, when new tissue must be formed. Undesirable vessel formation takes place in the event of tumour growth. The tumour receives nutrition from the new blood vessels and can also spread via newly formed lymph vessels, thus prevention of vessel growth is desirable in this situation.

A major challenge in the field of medicine is understanding the signals governing the way vessels are formed. It has been proposed that targeted signals so-called gradients from growth factors instruct the vessels as to the direction in which they are to grow.

"Our study shows that a simple gradient from a signal protein is sufficient to tell the blood vessel cell in which direction it is to move. We have also been able to show that the form of the gradient governs the way in which the cell moves," says Irmeli Barkefors, a postgraduate student at Uppsala University.

The research group is now going to develop the method further. The aim is to be able to study targeted migration in complicated organ culture systems, whereby interaction between different cell types can be studied.

"The method can basically be adapted to facilitate study of all types of cells. It is particularly important to study the mechanisms that determine whether or not cancer cells spread," says researchers Johan Kreuger, who has been heading the project.


'/>"/>

Contact: Dr. Johan Kreuger
johan.kreuger@imbim.uu.se
46-073-394-9094
Uppsala University
Source:Eurekalert

Page: 1

Related medicine news :

1. Ranbaxy Receives Tentative Approval to Manufacture and Market Galantamine Tablets on an Exclusive Basis
2. APHA Urges President Bush to Reconsider Unfounded Basis for SCHIP Veto
3. The structural basis of familial hypertrophic cardiomyopathy is revealed
4. American Association for Homecare Disputes Validity of Internet Power Wheelchair Prices as Basis for Reimbursement of Services in Medicare
5. HSA Plans are Covering Preventive Care on a First-Dollar Basis
6. New book presents comprehensive survey of research into the molecular basis of aging
7. Twins study shows genetic basis for face and place recognition
8. MITs McGovern Institute researchers awarded $8.5M to study brain basis of autism and dyslexia
9. KV Pharmaceutical Reports Record Revenues for Fiscal 2008 Third Quarter and Year-to-Date on a Preliminary Basis
10. Not all risk is created equal
11. New Case Study Details How an Illinois Hospital Created a Safe Lifting Team that Dramatically Reduced Injuries, Increased Staff Satisfaction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/29/2016)... ... May 29, 2016 , ... Whole Health Supply is ... new KlipPro KP-240L clipper is available to the public. This is an unusual clipper ... wider than the average clipper. , Everything about this product is concentrated on ease ...
(Date:5/28/2016)... Aliso Viejo, California (PRWEB) , ... May 28, 2016 , ... ... just need to drag and drop a preset onto their media," said Christina Austin ... from Pixel Film Studios, editors can quickly and easily add stylish color grades to ...
(Date:5/28/2016)... ... May 28, 2016 , ... In a part of the city where’s it’s easy to spot ... Kelowna restaurants is hoping to attract diners with a taste for real food. ... opened the doors to Cornerstone Grill, an urban casual restaurant focusing on dishes made by ...
(Date:5/27/2016)... ... 2016 , ... Two director-level employees of Horizon Blue Cross Blue Shield of ... 2016 honorees. The award recognizes businesswomen who excel in their fields and who ... the MLTSS (Managed Long-Term Services and Supports) Program at Horizon NJ Health and Theresa ...
(Date:5/27/2016)... ... ... With over 60 percent of acute stroke survivors being left unable to ... in the rehabilitation process has steadily increased. Ekso Bionics had been working to help ... stroke. , Ekso Bionics has now received clearance from the U.S. Food and Drug ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... , May 27, 2016 ... the Dario™ Diabetes Management Tool, today announced that the Company,s ... the Marcum MicroCap Conference being held June 1-2 in ... Invitational, being held June 7-9 in Los Angeles, ... will discuss recent corporate and operational milestones, including the U.S. ...
(Date:5/27/2016)... May 27, 2016 ... company focused on late-stage drug development, today announced ... of pivotal batches required for registration of ... (FDA). This follows Kitov,s announcement in ... successfully met its primary efficacy endpoint. ...
(Date:5/26/2016)... ALBANY, New York , May 26, 2016 ... Transparency Market Research "Medical Waste Management Market - U.S. Industry ... the medical waste management market in the U.S. was valued ... expand at a CAGR of 3.4% from 2015 to 2023 ... report provides exhaustive analysis of current and emerging needle free ...
Breaking Medicine Technology: