Navigation Links
Barrow researchers successfully destroy brain tumor cells
Date:12/4/2012

Phoenix, AZ Dec. 2, 2012) -- A team of brain cancer researchers at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center has effectively treated brain tumor cells using a unique combination of diet and radiation therapy. The study, "The Ketogenic Diet Is an Effective Adjuvant to Radiation Therapy for the Treatment of Malignant Glioma," was published in PLOS ONE.

Led by Adrienne C. Scheck, PhD, Principal Investigator in Neuro-Oncology and Neurosurgery Research at Barrow, the groundbreaking research studied the effects of the ketogenic diet in conjunction with radiation therapy for the treatment of malignant gliomas, an aggressive and deadly type of brain tumor. The ketogenic diet is a high-fat, low-carbohydrate diet that alters metabolism and is used in the treatment of pediatric epilepsy that does not respond to conventional therapies. The diet's affects on brain homeostasis have potential for the treatment of other neurological diseases, as well.

In the study, mice with high-level malignant gliomas were maintained on either a standard or a ketogenic diet. Both groups received radiation therapy. Dr. Scheck's team discovered that animals fed a ketogenic diet had an increased median survival of approximately five days relative to animals maintained on a standard diet. Of the mice that were fed a ketogenic diet and received radiation, nine of 11 survived with no signs of tumor recurrence, even after being switched back to standard food, for over 200 days. None on the standard diet survived more than 33 days.

One theory behind the success of the treatment is that the ketogenic diet may reduce growth factor stimulation, inhibiting tumor growth. Barrow scientists also believe that it may reduce inflammation and edema surrounding the tumors. This is believed to be the first study of its kind to look at the effects of the ketogenic diet with radiation.

Dr. Scheck believes that the study has promising implications in the treatment of human malignant gliomas. "We found that the ketogenic diet significantly enhances the anti-tumor effect of radiation, which suggests that it may be useful as an adjuvant to the current standard of care for the treatment of human malignant gliomas," she says.

Dr. Scheck adds that the ketogenic diet could quickly and easily be added into current brain tumor treatment plans as an adjuvant therapy without the need for FDA approval. She is currently exploring options for clinical trials.


'/>"/>
Contact: Lynne Reaves
lynne.reaves@dignityhealth.org
602-406-4734
St. Joseph's Hospital and Medical Center
Source:Eurekalert

Related medicine news :

1. Barrow researchers use magic for discoveries
2. Western University researchers make breakthrough in arthritis research
3. Researchers report first success of targeted therapy in most common non-small cell lung cancer
4. USC, Oxford researchers find high fructose corn syrup-global prevalence of diabetes link
5. Researchers study cry acoustics to determine risk for autism
6. Researchers explore social media as preventative method for infectious diseases
7. New mechanism for cancer progression discovered by UNC and Harvard researchers
8. Researchers identify physiological evidence of chemo brain
9. Researchers find chemical switches for neurodegenerative diseases
10. Release all Tamiflu data as promised, argue researchers
11. Researchers link new molecular culprit to breast cancer progression
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... Wallingford, CT (PRWEB) , ... March 28, 2017 ... ... hemostatic devices, announces today that the University of Pittsburgh Medical Center (UPMC) will ... Central and Western Pennsylvania. , The program, developed in association with efforts by ...
(Date:3/28/2017)... (PRWEB) , ... March 28, 2017 , ... Usually, the ... the daily wardrobe. However, for those self-conscious about a double chin, this means more ... the ideal solution. , “For most people, a double chin is undesirable,” Dr. ...
(Date:3/28/2017)... ... March 28, 2017 , ... Calibration, ... to ensuring high-quality results and maintaining GMP and USP compliance. In a new ... accordance with GMP requirements " these requirements are explained. The challenge is ...
(Date:3/28/2017)... (PRWEB) , ... March 28, 2017 , ... ... in Wethersfield, Conn., has relocated its corporate headquarters to a new, more expansive ... , In October 2016, Qualidigm purchased a distressed office building in Wethersfield, ...
(Date:3/28/2017)... ... March 28, 2017 , ... With less than 10,000 dermatologists in the United ... can be limited while the desire to conquer breakouts and eliminate skincare stress is ... every customer online, today released its inaugural survey on the State of Acne in ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... LightIntegra Technology Inc. today announced that its ... President and Chief Executive Officer effective March 13, 2017. ... Directors of LightIntegra. Paul Geyer will continue ... "This is the perfect time for Bill ... We,ve selected a very strong leader at a time ...
(Date:3/27/2017)... 2017  Sanderling Ventures, portfolio company, Torax Medical, ... of Johnson & Johnson. Torax manufactures and markets the ... gastro-esophageal reflux disease (GERD). The LINK device is ... the procedure is currently available in the U.S. ... was founded by Sanderling Ventures, Mayo Medical Ventures ...
(Date:3/27/2017)... March 27, 2017 FinancialBuzz.com News Commentary  ... Based on New Frontier ... states where cannabis is legal will generate $655 million in taxes ... from cannabis specific taxes, such as Washington State,s ... be earned from state sales taxes that are applied on all ...
Breaking Medicine Technology: