Navigation Links
Balloon Valve May Be Alternative to Open-Heart Surgery
Date:11/4/2007

It props open closed aortas in older patients, research suggests

SUNDAY, Nov. 4 (HealthDay News) -- Older, high-risk heart patients with narrowed aortas who typically need open-heart surgery might someday have a new, less invasive option -- an implanted, balloon-expandable aortic valve.

The balloon is inserted percutaneously (through the skin), placed across the problem valve and then inflated, experts said. In a new study, the procedure -- not yet approved by the U.S. Food and Drug Administration -- showed real health benefits for up to two years.

The research is to be presented Sunday at the American Heart Association annual meeting in Orlando, Fla.

"The percutaneous balloon expandable aortic valve insertion provides a safe and sustained alternative for high-risk patients with severe aortic stenosis [closure]," said lead researcher Dr. Sanjeevan Pasupati, who was an interventional fellow at St. Paul's Hospital in Vancouver, British Columbia, when the study was conducted.

"In our first 100 high-risk patients, the intra procedural mortality was only 2 percent with minimal morbidity," Pasupati said. "Our long-term survival is promising, with 70 percent and 60 percent at one and two years, respectively. This procedure is here to stay."

Other experts stressed caution, however.

"This is a very exciting frontier for us in terms of being able to potentially fix these with percutaneous approach versus putting patients on a heart-lung machine," said Dr. John P. Erwin III, an associate professor of internal medicine at Texas A&M Health Science Center College of Medicine and a cardiologist with Scott & White Hospital in Temple. However, "this is still considered to be a high-risk procedure that is not quite ready for prime time at this point," he said.

According to the American Heart Association, aortic stenosis involves a blockage of the heart's aortic valve. The aorta is the body's main artery. The aortic valve closes over after each heartbeat to prevent blood from flowing back into the heart's left ventricle.

"Patients who have severe aortic stenosis and who may reach the criteria where they're best suited to have heart surgery often are very elderly and have other significant risk factors, so they're at high risk at the time they have open-heart surgery," Erwin explained. "There's a high prevalence of stroke and, in octogenarians, when we do bypass and place a valve, the combined mortality and major morbidity is about 25 percent."

So, physicians have long looked for an alternative to open-heart surgery.

For this study, balloon expandable aortic valves (BEAVs) were implanted in 100 patients, average age 83, of which slightly more than half were male. The procedure was successful in 91 (91 percent) of patients.

Two percent of the participants died during the procedure. At 30 days after surgery, 15 percent of the participants had died.

There was also "significant improvement" in heart function.

"Currently, this is not an alternative to surgery, and we need to await the results of the FDA-approved randomized PARTNER study," said Pasupati, who is now an interventional cardiologist at Waikato Hospital in Hamilton, New Zealand. "The technology has CE Marked approved [indicating conformity with European health and safety requirements] and is currently available in Europe."

"Definitely, it's going to be something to be watched, but that's only the Canadian trial," added Dr. Carlos Ruiz, director of the division of cardiac intervention for constructive heart disease at Lenox Hill Hospital in New York City. "There are the Canadian trial ongoing, the European trial, as well as the U.S. trial."

More information

Find out more about aortic valve stenosis at the American Heart Association.



SOURCES: Sanjeevan Pasupati, MBChB, FRACP, interventional cardiologist, Waikato Hospital, Hamilton, New Zealand; John P. Erwin III, M.D., associate professor of internal medicine, Texas A&M Health Science Center College of Medicine and cardiologist, Scott & White Hospital, Temple, Texas; Carlos Ruiz, M.D., Ph.D., director, division of cardiac intervention for constructive heart disease, Lenox Hill Hospital, New York City; Nov. 4, 2007, presentation, annual meeting, American Heart Association, Orlando, Fla.


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Hot Air Balloon Festival launched in Rajasthan
2. New Balloon Catheter Available Worldwide for Carotid and Renal Angioplasty
3. Disaster Balloons can Be Used to Keep Communication Intact During Calamities
4. Debate Focuses on Door-to-balloon Time in Heart Attack Treatment
5. Award for TTK Chitra heart valve prosthesis
6. Defective heart valve causes problems
7. Cardiac Valve Disease Linked To Genes
8. Mutations in NOTCH1 cause an early developmental defect in the aortic valve
9. Heart valve surgery may be replaced by new heart therapy
10. Percutaneous aortic valve replacement- a revolution in Cardiac Surgery
11. Laboratory Heart valve to study Heart diseases
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Balloon Valve May Be Alternative to Open-Heart Surgery
(Date:4/24/2017)... ... April 24, 2017 , ... Salus Telehealth, ... the company’s VideoMedicine mobile platform has launched Quick Care, a new service offering ... Quick Care provides patients with the option to request and begin a consultation ...
(Date:4/24/2017)... ... 24, 2017 , ... MAP Health Management announced today a ... with addiction who are served by MAP’s patient engagement ecosystem. Lief Therapeutics is ... heart and breath rates to identify anxiety levels and can provide biofeedback exercises ...
(Date:4/24/2017)... NJ (PRWEB) , ... April 24, 2017 , ... Come ... Plaza Hotel, 4200 Jim Walter Blvd, for an educational and exciting 2-day program. ... of our staff hearing this before they approach patients” about the course entitled Ain't ...
(Date:4/24/2017)... ... ... “Reflections of God’s Work”: an enlightening collection of life lessons leading each person ... author, Jerri Broglin, a survivor of great loss who gained insight on how to ... those searching for answers, as we are finding the answers that are so deep ...
(Date:4/24/2017)... ... April 24, 2017 , ... Life of Purpose Treatment is proud ... event will be held at 7:30 pm on May 10th at the University Auditorium. ... of Sister Hazel, will support the UF Collegiate Recovery Community (UFCRC). The concert will ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... 2017 Companion animal ... in pets such as canine, avian and feline. ... types such as Attenuated Live Vaccines, Conjugate Vaccines, ... and Recombinant Vaccines. Attenuated live vaccines are derived ... which have been weakend under laboratory conditions. Conjugate ...
(Date:4/18/2017)... 18, 2017 Cogentix Medical, Inc. (NASDAQ: CGNT), ... Urology, Uro/Gyn and Gynecology markets with innovative and proprietary ... ended March 31, 2017 after the market close on ... will host a conference call and webcast to discuss ... 2, 2017 at 4:30 p.m. Eastern Time (3:30 p.m. ...
(Date:4/18/2017)... , April 18, 2017  Socionext Inc. and ... started in 2016, in which Socionext extracts and ... The companies achieved initial results in reading ultrasound ... Artificial Brain SOINN. The results will be introduced ... April 19-21, at booths 4505 & 4507. ...
Breaking Medicine Technology: