Navigation Links
Balancing the womb
Date:12/21/2011

New research hopes to explain premature births and failed inductions of labour. The study by academics at the University of Bristol suggests a new mechanism by which the level of myosin phosphorylation is regulated in the pregnant uterus.

The researchers, Dr Claire Hudson and Professor Andrs Lpez Bernal in the School of Clinical Sciences and Dr Kate Heesom in the University Proteomics Facility and the School of Biochemistry, have discovered that phosphorylation of uterus proteins at specific amino acids have a key role in the regulation of uterine activity in labour.

A remarkable feature of the uterus (the womb) is that it remains relatively relaxed for the nine months of pregnancy, carrying the baby safely, and then, during labour, it contracts forcibly and the baby is born. A special type of smooth muscle that grows and stretches during pregnancy to accommodate the fetus and the placenta forms the uterus.

Hormones such as oxytocin or prostaglandins promote labour, but the biochemical changes that allow the switch from relaxation to contractions to happen are not fully understood. This makes it difficult to predict when a woman is going to deliver. In eight to ten per cent of women delivery occurs too early (preterm labour, before 37 weeks' gestation) and prematurity is associated with major risks for the baby. On the other hand when labour has to be induced for medical reasons, it is impossible to know whether the induction will be successful or whether it will require an emergency caesarean section with risks for the mother and baby.

Using small biopsies of uterine tissue from women who delivered at St Michael's Hospital, Dr Hudson has demonstrated that contractions require both a calcium dependent pathway driven by myosin kinase and a calcium independent pathway that regulates the activity of myosin phosphatase. Additionally, Dr Hudson has pinpointed precisely the position of the amino acids in myosin and myosin
'/>"/>

Contact: Joanne Fryer
joanne.fryer@bristol.ac.uk
44-117-331-7276
University of Bristol
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Parenting after the death of a child a difficult balancing act: York U study
2. 'The Balancing Act' & Chicken of the Sea Search for America's 'Supercook'
3. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes Dr. Bob Arnot to the Program
4. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes HSA Bank to the Program
5. O2 Media's Hit Morning TV Show ‘The Balancing Act' Welcomes Absolute Miracle Cream to the Program
6. ‘The Balancing Act' and Chicken of the Sea Search for America's ‘Supercook'
7. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes Dexter Russell, Inc. to the Program
8. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes Resident Chef Jeremy Hanlon to the Program
9. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes the Arthritis Foundation to the Program
10. O2 Media's Hit Morning TV Show ‘The Balancing Act' Welcomes Atkins Nutritionals to the Program
11. Natures Peak Products Along With Company President Paul Wilkinson Were Recently Featured on Segment of Lifetime TV Networks Nationally Broadcast Show The Balancing Act
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... Dr. Joseph Furlin MD, a certified obstetrician ... practices; OB GYN in Melrose Park, IL and ... contains important information about each of the care services and ... forms in English and Spanish. The navigation of the ... the website provide Dr. Furlin’s patients with important information regarding ...
(Date:10/30/2014)... October 30, 2014 USARAD ... Accredited teleradiology and specialty telemedicine solutions provider, including ... to its existing teleradiology services at Mission Bend ... and expert telemedicine services, to the state-of-the-art, 24/7, ... a result of this innovative partnership, there will ...
(Date:10/30/2014)... The annual meeting of The ... close on Saturday, October 18th, marking the end of ... 1989. NAMS is North America’s leading non-profit organization dedicated ... all women during midlife and beyond through an understanding ... and thought leaders from fields as varied as gynecology, ...
(Date:10/30/2014)... 29, 2014 (HealthDay News) -- When it comes to heart ... men to delay care when they have symptoms that spell ... to the hospital with a more severe or advanced stage ... study author Catherine Kreatsoulas, a Fulbright Scholar and research fellow ... news release from the Heart and Stroke Foundation of Canada. ...
(Date:10/30/2014)... By Dennis Thompson ... -- Drinking lots of milk could be bad for your ... that the calcium in milk can help strengthen bones and ... health officials to recommend milk as part of a healthy ... amounts of milk did not protect men or women from ...
Breaking Medicine News(10 mins):Health News:Dr. Joseph Furlin Launches New Website with Information about Care Services 2Health News:USARAD HOLDINGS INC, SECONDOPINIONS.COM® Pioneers Specialty On-Demand Telemedicine And Second Opinion Service At Houston-Based, Mission Bend Freestanding ER Chain 2Health News:USARAD HOLDINGS INC, SECONDOPINIONS.COM® Pioneers Specialty On-Demand Telemedicine And Second Opinion Service At Houston-Based, Mission Bend Freestanding ER Chain 3Health News:Highlights from The North American Menopause Society 25th Annual Meeting 2Health News:Highlights from The North American Menopause Society 25th Annual Meeting 3Health News:Women Often Ignore Signs of Heart Trouble 2Health News:Is Milk Your Friend or Foe? 2Health News:Is Milk Your Friend or Foe? 3
... have newly identified 34 unique variations in the human ... sclerosis (ALS). ,The 34 so-called single nucleotide ... to the non-inherited form of the fatal neurodegenerative disease. ... responsible for sporadic ALS, our results seriously narrow the ...
... arteries and giving blood at six-monthly intervals to promote iron reduction ... ,A normal adult has five to six litres of blood ... blood donation. This blood is replaced by the body within 24 ... VA Medical Centre and the Dartmouth Medical School in Vermont looked ...
... for primary ciliary dyskinesia, a rare genetic disease that ... ,According to Thomas Ferkol, M.D., Washington University School of ... of patients with primary ciliary dyskinesia (PCD) have a ... of PCD requires a high index of suspicion, but ...
... such as Tenormin, Inderal and Lopressor should not be a ... a large new review of studies. ,The review, ... that beta-blocker users have a slightly higher risk of death ... such as Norvasc and Cardizem to manage their blood pressure. ...
... determined that low levels of a protein in the blood ... artery disease. ,In a group of men ... Activation, Normal T-cell Expressed, and Secreted), also known as CCL5, ... ,RANTES is a chemokine produced by a variety ...
... breast cancer prevention among women at high risk of the ... found that the breast cancer risk reduction persists long after ... to treat breast cancer and to prevent it among women ... data on tamoxifen for breast cancer prevention comes from the ...
Cached Medicine News:Health News:Human Genetic Code for ALS Identified 2Health News:Newborns With Respiratory Distress Potentially Have Rare Genetic Disease 2Health News:Newborns With Respiratory Distress Potentially Have Rare Genetic Disease 3Health News:Beta-Blockers Should Not Be First Choice for High Blood Pressure 2Health News:Tamoxifen Yields Long-term Reduction in Breast Cancer Risk 2Health News:Tamoxifen Yields Long-term Reduction in Breast Cancer Risk 3
(Date:10/30/2014)... VIEW, Calif. , Oct. 30, 2014 /PRNewswire/ ... accelerated dramatically as a result of government initiatives ... time - healthcare providers have invested over the ... the heart of health IT, and U.S. clinicians ... Logo - http://photos.prnewswire.com/prnh/20141029/155278LOGO ...
(Date:10/30/2014)... FRANCISCO , Oct. 30, 2014  Nektar Therapeutics ... results for the third quarter ended September 30, 2014 ... U.S.-based financial markets. Howard Robin , president and ... review the results beginning at 5:00 p.m. Eastern Time ... press release and a live audio-only Webcast of the ...
(Date:10/30/2014)... 30, 2014  CytRx Corporation (NASDAQ: ... specializing in oncology, today announced an upcoming presentation ... candidate, aldoxorubicin.  The presentation, titled, "Drug Conjugates Bind ... given by Sant P. Chawla , M.D., ... principal investigator of the Company,s ongoing global, pivotal ...
Breaking Medicine Technology:Electronic Health Record Usability: CIOs Weigh In 2Electronic Health Record Usability: CIOs Weigh In 3Electronic Health Record Usability: CIOs Weigh In 4Nektar to Announce Financial Results for the Third Quarter 2014 on Thursday, November 6, 2014, After Close of U.S.-Based Financial Markets 2CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 2CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 3CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 4
... YORK, Sept. 9 New York Blood Center (NYBC), serving ... Island, the Hudson Valley and New Jersey, calls upon our ... and Labor Day holiday weekend have resulted in fewer donations ... B-negative blood for patients in need. Donations from ...
... Polycystic Ovarian Syndrome, known as PCOS, is a silent ... body and increases the risk of serious illness. ... and increases the risk of heart disease, insulin resistance, diabetes ... abnormality in women of child bearing age, affecting 5 to ...
Cached Medicine Technology:Blood Donors Needed as School, Fall Season Returns 2Blood Donors Needed as School, Fall Season Returns 3Detailed Cholesterol Test Provides Vital Clues for Women in Search of PCOS Answers 2Detailed Cholesterol Test Provides Vital Clues for Women in Search of PCOS Answers 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: