Navigation Links
Baicalin inhibits neurotoxicity of colistin sulfate effectively
Date:12/4/2013

Baicalin, a type of flavonoid extracted from the dried root of Scutellaria baicalensis georgi, has been shown to effectively inhibit cell apoptosis. Colistin sulfate, a cyclic cationic polypeptide antibiotic, has been shown to have renal and neurological side effects. Dr. Hong Jiang and colleagues from Northeast Agricultural University assumed that baicalin would suppress colistin sulfate-induced neuronal apoptosis. In a study by Jiang et al, PC12 cells were pretreated with baicalin (25, 50 and 100 μg/mL), and exposed to 125 μg/mL colistin sulfate. Cell morphology markedly changed, and cell viability increased. Moreover, caspase-3 activity, lactate dehydrogenase level and free radical content decreased. Experimental results indicated that baicalin inhibited colistin sulfate-induced PC12 cell apoptosis by suppressing free radical injury, and reducing caspase-3 activity and lactate dehydrogenase activity. These findings are published in the Neural Regeneration Research (Vol. 8, No. 28, 2013).


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related medicine news :

1. Bloodstream scavenger inhibits clotting without increased bleeding
2. Molecule found that inhibits recovery from stroke
3. New monoclonal antibody inhibits tumor growth in advanced solid tumors in phase I clinical trial
4. Kentucky team inhibits Alzheimers biomarkers in animal model by targeting astrocytes
5. TG02 Potently Inhibits the Proliferation and Survival of Multiple Myeloma Cell Lines through Depletion of the Key Survival Protein MCL-1
6. Mayo Clinic finds experimental drug inhibits growth in all stages of common kidney cancer
7. Breast cancer effectively treated with chemical found in celery, parsley by MU researchers
8. First-of-its-kind approach nanomedicine design effectively targets cancer with decreased toxicity
9. ShopPharmacyCounter.com Unveils PhenObestin 37.5 to Offset Obesity Effectively
10. Increase Height Naturally
11. Can “Grow Taller 4 Idiots” Help People Boost Their Height Effectively – Health Review Center
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Baicalin inhibits neurotoxicity of colistin sulfate effectively
(Date:1/24/2017)... ... 2017 , ... The results from the American Cancer Society’s newest ... prostate cancer patients: incidents of cancer is down as is the likelihood of prostate ... rate has dropped from its peak of 215.1 in 1991 to 161.2 in 2014 ...
(Date:1/24/2017)... ... January 24, 2017 , ... Today, Taza ... latest award-winning bottles, designed specifically to optimize the drinking experience for K-Cup coffee, ... renowned for introducing the world’s first untouched bottled water purposed exclusively for creating ...
(Date:1/24/2017)... ... January 24, 2017 , ... “Choosing Wisdom-Solomon’s ... finances, friendship, marriage, leadership, gossip, prostitution, adultery, anger, and common sense. , ... Judith Coats and Dr. David Coats. In September of 1983, they flew to ...
(Date:1/24/2017)... ... January 24, 2017 , ... “The Octagon of Spiritual Balances”: ... of Spiritual Balances” is the creation of published author, Pastor Bernard J. Weathers, pastor ... holds a bachelor degree in religious education and a master degree in theology. , ...
(Date:1/24/2017)... ... January 23, 2017 , ... The Pharmacy and Medically ... the bipartisan original co-sponsorship of nearly one-quarter of the U.S. House of Representatives. ... of Chain Drug Stores (NACDS) strongly backs the legislation. , “NACDS thanks for ...
Breaking Medicine News(10 mins):
(Date:1/24/2017)... January 24, 2017 The global  active pharmaceutical ingredients ... by 2025, based on a new report by Grand View Research, Inc. ... to drive the market over the forecast period. Advancements in recombinant molecular ... to boost growth.  Continue Reading ... ...
(Date:1/24/2017)... 2017 Optoelectronic components have the capability ... interaction of these components with light makes them ... of applications. These components are primarily used in ... healthcare among others. Growing application across ... power consumption, reliability, scalability, and performance is fueling ...
(Date:1/24/2017)... The global peripheral I.V. catheter market accounted ... expected to grow at a CAGR of 6.0% during ... larger share in the global market between the two ... the hospital segment accounted for the highest share in ... peripheral I.V. catheter market is witnessing high growth rate, ...
Breaking Medicine Technology: