Navigation Links
Baicalin inhibits neurotoxicity of colistin sulfate effectively
Date:12/4/2013

Baicalin, a type of flavonoid extracted from the dried root of Scutellaria baicalensis georgi, has been shown to effectively inhibit cell apoptosis. Colistin sulfate, a cyclic cationic polypeptide antibiotic, has been shown to have renal and neurological side effects. Dr. Hong Jiang and colleagues from Northeast Agricultural University assumed that baicalin would suppress colistin sulfate-induced neuronal apoptosis. In a study by Jiang et al, PC12 cells were pretreated with baicalin (25, 50 and 100 μg/mL), and exposed to 125 μg/mL colistin sulfate. Cell morphology markedly changed, and cell viability increased. Moreover, caspase-3 activity, lactate dehydrogenase level and free radical content decreased. Experimental results indicated that baicalin inhibited colistin sulfate-induced PC12 cell apoptosis by suppressing free radical injury, and reducing caspase-3 activity and lactate dehydrogenase activity. These findings are published in the Neural Regeneration Research (Vol. 8, No. 28, 2013).


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related medicine news :

1. Bloodstream scavenger inhibits clotting without increased bleeding
2. Molecule found that inhibits recovery from stroke
3. New monoclonal antibody inhibits tumor growth in advanced solid tumors in phase I clinical trial
4. Kentucky team inhibits Alzheimers biomarkers in animal model by targeting astrocytes
5. TG02 Potently Inhibits the Proliferation and Survival of Multiple Myeloma Cell Lines through Depletion of the Key Survival Protein MCL-1
6. Mayo Clinic finds experimental drug inhibits growth in all stages of common kidney cancer
7. Breast cancer effectively treated with chemical found in celery, parsley by MU researchers
8. First-of-its-kind approach nanomedicine design effectively targets cancer with decreased toxicity
9. ShopPharmacyCounter.com Unveils PhenObestin 37.5 to Offset Obesity Effectively
10. Increase Height Naturally
11. Can “Grow Taller 4 Idiots” Help People Boost Their Height Effectively – Health Review Center
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Baicalin inhibits neurotoxicity of colistin sulfate effectively
(Date:4/21/2017)... ... April 21, 2017 , ... Providing broad access to ... opposition, but there is a better way to address this problem. , That was ... Pharmacy, Public Policy and Economics at the University of Southern California, who served as ...
(Date:4/21/2017)... , ... April 21, 2017 , ... Brady ... that its B-595 and B-7569 vinyl label materials received certification ... warning labels are tested to remain intact and legible, for use on chemical drums ...
(Date:4/21/2017)... ... April 21, 2017 , ... ... been named Agency of Record (AOR) for Theravent, Inc. , the makers ... Theravent’s parent company, Foundation Consumer Healthcare, is now working to expand distribution in ...
(Date:4/21/2017)... (PRWEB) , ... April 21, 2017 , ... ... products, announced an exciting new partnership with the highly regarded and well renowned ... Management’s highly innovative, myTAP & myTAP PAP Nasal Pillow Mask, and will stabilize ...
(Date:4/21/2017)... Salt Lake City, UT (PRWEB) , ... April 21, 2017 , ... ... medical staffing solutions, recently partnered with Advanced Patient Care of Utah (APCUT) and has ... the way for the next chapter of growth for our agency and our ability ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... 2017  SARES•REGIS Group leased the first of ... Conejo Spectrum Business Park in Thousand ... Inc. , a biopharmaceutical company developing meaningful therapies ... have been underserved by scientific innovation, with an ... autoimmune and infectious disease. Before commencement ...
(Date:4/18/2017)... Research and Markets has announced the addition of the "Global ... ... at a CAGR of 6.35% during the period 2017-2021. ... based on an in-depth market analysis with inputs from industry experts. ... the coming years. The report also includes a discussion of the ...
(Date:4/18/2017)... Research and Markets has announced the addition of the ... Radiopharmaceuticals Market, Forecast to 2023" report to their offering. ... This report assesses ... growth in the number of unit shipments over the next ... design and manufacture molecular imaging equipment. Market ...
Breaking Medicine Technology: