Navigation Links
Bacterial imbalance contributes to intestinal inflammation and carcinogenesis
Date:1/2/2013

Instability in the composition of gut bacterial communities (dysbiosis) has been linked to common human intestinal disorders, including inflammatory bowel disease and colorectal cancer; however, it is unclear if dysbiosis can instigate disease or if it is a consequence of the underlying disorder. In this issue of the Journal of Clinical Investigation, researchers led by Mathias Chamaillard at the University Lille Nord de France in Lille, France, examined intestinal inflammation and tumorigenesis in a mouse model of dysbiosis. Dysbiosis enhanced intestinal inflammation and increased the risk for inflammation-associated colon cancer. Treatment with antibiotics or transplantation of fecal material from normal mice reduced disease risk and instigated long-term, beneficial alterations in intestinal bacteria. Conversely, transplantation of normal mice with dysbiotic fecal material increased intestinal inflammation and enhanced the risk of inflammation-associated colon cancer. These results demonstrate that gut bacterial communities play an integral role in protecting against intestinal inflammation and associated tumorigenesis.


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related medicine news :

1. Pharmacy Robots Linked to Bacterial Contamination of Drugs
2. Children with juvenile arthritis have higher rates of bacterial infection
3. University of Minnesota startup to treat challenging bacterial infection
4. Fish Pedicure a Recipe for Bacterial Infection, Researchers Warn
5. Zooming in on bacterial weapons in 3-D
6. Killer stainless steel: New process gives icon of cleanliness antibacterial coating
7. Study Ties Kids Allergy Risks to Antibacterials, Preservatives
8. Bacterial Vaginosis Increases Female-to-Male HIV Transmission Risk
9. New mechanism of bacterial pathogenesis discovered
10. AuCoin gets $600,000 to refine new test for deadly bacterial infection melioidosis
11. NIH uses genome sequencing to help quell bacterial outbreak in Clinical Center
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2017)... (PRWEB) , ... March 27, 2017 , ... ... recently received the CE Certificate of Conformity for the Smart System® 20/20. CE ... exceed the highest industry standards and specifications such as ANSI, ISO and proven ...
(Date:3/27/2017)... (PRWEB) , ... March 27, 2017 , ... ... can quickly sideline athletes. A type of groin injury, it occurs when the ... to serious, intense pain in and around the lower torso, as well as ...
(Date:3/27/2017)... (PRWEB) , ... March 27, 2017 , ... ... epigenetic research products enables researchers to pursue the recent RNA methylation “gold rush” ... . In light of the newfound characteristics of N6-methyladenosine, or m6A , ...
(Date:3/27/2017)... ... ... Schloz is still in shock after receiving a $2,500 Academic Award from California Casualty ... said. , She thinks the coming week is going to be a very joyful for ... help my students.” , The award will allow the 4th grade teacher at Tumwater Hill ...
(Date:3/27/2017)... ... March 27, 2017 , ... Sodium determination is consistently becoming ... require expert user knowledge. In a live webinar on April 11th and October ... highly accurate, determination of sodium. , It has long been known that too ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... , March 27, 2017  Impax Laboratories, Inc. ... appointed Paul M. Bisaro as Impax,s President ... Company,s Board, effective March 27, 2017. Mr. Bisaro will ... as Interim President and Chief Executive Officer since December ... generic and branded pharmaceutical experience, Mr. Bisaro, 56, is ...
(Date:3/27/2017)... SAN DIEGO , March 27, 2017 ... biopharmaceutical company focused on developing novel, small molecule drugs across ... Company,s President and Chief Executive Officer, will present a corporate ... April 4 at 3:40pm ET.  The conference will take place ... in New York , NY.  ...
(Date:3/24/2017)... PUNE, India , March 24, 2017 According to ... Global Opportunity Analysis and Industry Forecast, 2014-2022," the spine bone stimulators market was ... by 2022, growing at a CAGR of 3.6% during the forecast period. ... ... Allied Market Research Logo ...
Breaking Medicine Technology: