Navigation Links
Bacteria with a built-in thermometer
Date:5/20/2009

Researchers in the "Molecular Infection Biology group" at the Helmholtz Centre for Infection Research (HZI) in Braunschweig and the Braunschweig Technical University could now demonstrate for the first time that bacteria of the Yersinia genus possess a unique protein thermometer the protein RovA - which assists them in the infection process. RovA is a multi-functional sensor: it measures both the temperature of its host as well as the host's metabolic activity and nutrients. If these are suitable for the survival of the bacteria, the RovA protein activates genes for the infection process to begin. These results have now been published in the current online edition of the PLoS Pathogens science magazine.

Yersinia can trigger various different diseases: best well-known is the Yersinia pestis type which caused the Plague in medieval times. This led to the death of around a third of Europe's population. The Yersinia enterocolitica and Yersinia pseudotuberculosis species cause an inflammation of the intestines following food poisoning: the bacteria infect the cells of the intestines, leading to heavy bouts of diarrhoea. The Yersinia bacteria contain invasin as a surface protein to help them penetrate the intestinal cells. The immune cells quickly identify this so-called virulence factor as a danger and launch an immune response. To avoid this, the bacteria quickly lose the invasin soon after entering the body. The germs then adapt their metabolism and feed on the nutrients prepared by the host cells. They also produce substances which kill off the body's defence cells, such as phagocytes. Little was known about how Yersinia is able to regulate these individual stages of infection until now.

Researchers at the HZI, led by Petra Dersch, have now identified how these mechanisms work. The RovA protein plays a key role. The protein reads the temperature for the bacteria. Depending on the environme
'/>"/>

Contact: Dr. Bastian Dornbach
bastian.dornbach@helmhotz-hzi.de
49-053-161-811-407
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Veterinarians at high risk for viral, bacterial infections from animals
2. Sterilize the Flu Virus and Bacteria in Home Air with Alen Corp.'s New HEPA UV Air Purifiers
3. New UVC Kit Destroys Microorganisms Including flu Viruses, Bacteria and Mold
4. Autoantibodies may be created in response to bacterial DNA
5. Hospital Approved Residential Water Features Kill Harmful Airborne Bacteria
6. FDA Approves New Indication for Wyeths TYGACIL (tigecycline) for the Treatment of Adult Patients with Community-Acquired Bacterial Pneumonia
7. Simple device can ensure food gets to the store bacteria free
8. Most bacteria from craft goats cheese come from lactic acid and could be beneficial for health
9. Gut instinct: Salmonella bacterias molecular tactics to cause illness
10. Friendly Bacteria Improve Health Segment Broadcasts On The National Medical Report
11. Experimental TB drug explodes bacteria from the inside out
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... 13, 2014 The North American water storage ... 2013 to $5,450 million by 2018, at a CAGR of ... is expanding at a rapid pace in North America. The ... laws on water & wastewater storage and collection, and the ... market is expanding at a healthy rate in Canada, and ...
(Date:7/13/2014)... (PRWEB) July 13, 2014 The ... Copper, Molybdenum, Iron), Form (Chelated & Non Chelated), ... Geography - Global Trends and Forecast to 2018” ... with an analysis and forecasting of the global ... identifies the driving and restraining factors for the ...
(Date:7/13/2014)... (PRWEB) July 13, 2014 Fuel additives ... as gasoline, diesel, jet fuel, kerosene, and so on, ... also responsible for reducing the corrosion effects caused by ... when added to any fuel, provide economies of scale ... these escalate the overall cost of the fuel products. ...
(Date:7/13/2014)... 2014 MarketsandMarkets recently conducted a ... 3D Scanning; 3D rendering; Layout and Animation; Image ... - 2018)”, which analyzes and studies the major ... Western Europe, Eastern Europe, Middle East and Africa, ... the competitive landscape of the 3D imaging market, ...
(Date:7/13/2014)... Serena Gordon HealthDay ... A new type of sensor for people with diabetes ... using saliva instead of blood, researchers report. Scientists at ... tested it using artificial saliva. It uses light, metal and ... sugar. "Everybody knows that diabetics have to prick their ...
Breaking Medicine News(10 mins):Health News:North American Water Storage Systems Market is Expected to Reach $5,450 million by 2018 - New Report by MicroMarket Monitor 2Health News:North American Water Storage Systems Market is Expected to Reach $5,450 million by 2018 - New Report by MicroMarket Monitor 3Health News:Micronutrient Market Worth $6,474.6 Million by 2018 - A Report by MarketsandMarkets 2Health News:Micronutrient Market Worth $6,474.6 Million by 2018 - A Report by MarketsandMarkets 3Health News:Micronutrient Market Worth $6,474.6 Million by 2018 - A Report by MarketsandMarkets 4Health News:North America Fuel Additives Market is Expected to Reach $8,100 Million by 2017 - New Report by MicroMarket Monitor 2Health News:North America Fuel Additives Market is Expected to Reach $8,100 Million by 2017 - New Report by MicroMarket Monitor 3Health News:North America Fuel Additives Market is Expected to Reach $8,100 Million by 2017 - New Report by MicroMarket Monitor 4Health News:3D Imaging Market Worth $9.82 Billion By 2018 - Report by MarketsandMarkets 2Health News:3D Imaging Market Worth $9.82 Billion By 2018 - Report by MarketsandMarkets 3Health News:3D Imaging Market Worth $9.82 Billion By 2018 - Report by MarketsandMarkets 4Health News:Saliva Test Might Someday Replace Needle Prick for Diabetics 2Health News:Saliva Test Might Someday Replace Needle Prick for Diabetics 3
... joint researchers continue to seek better ways to diagnose ... following total joint arthroplasty. Their latest research shows ... tract infections, can also have a role in rapid ... previous work conducted by Javad Parvizi, MD, FRCS, director ...
... HealthDay Reporter , MONDAY, Feb. 6 (HealthDay News) -- ... like those found on the tongue -- that can "taste" ... foods and beverages. Nutrition experts have warned that Americans take ... bolster their concerns. In lab studies of pancreas cells ...
... , MONDAY, Feb. 6 (HealthDay News) -- Treatment with ... a slightly increased risk of death, a new analysis ... be taken into account by doctors and patients, according ... investigators analyzed the findings of 10 clinical trials that ...
... A recent discovery by Van Andel Research Institute (VARI) ... drug therapies for glioblastoma the most common and ... study, published in January in the Proceedings of ... characterized by cell signaling activation and gene amplification for ...
... for 30 years, has finally provided convincing evidence that ... symptoms of painful menstrual periods reports scientists from the ... published in Europes leading reproductive medicine journal Human ... have suggested that the combined oral contraceptive pill could ...
... Infectious disease has joined poaching and habitat loss as ... apes as they have become restricted to ever-smaller populations. ... our closest living relatives from ecological extinction are largely ... major threats and find innovative solutions. In response ...
Cached Medicine News:Health News:Rothman Institute at Jefferson research suggests use of LE strips to diagnose PJI 2Health News:Pancreas May 'Taste' Fructose, Hinting at Links to Diabetes 2Health News:Pancreas May 'Taste' Fructose, Hinting at Links to Diabetes 3Health News:Certain Cancer Drugs May Have Fatal Side Effects: Analysis 2Health News:Discovery predicts patient sensitivity to important drug target in deadly brain cancer 2Health News:Combined oral contraceptive pill helps painful periods 2Health News:Combined oral contraceptive pill helps painful periods 3Health News:Combined oral contraceptive pill helps painful periods 4Health News:Researchers examine consequences of non-intervention for infectious disease in African great apes 2Health News:Researchers examine consequences of non-intervention for infectious disease in African great apes 3
(Date:7/11/2014)... , July 11, 2014  Australian drug delivery company, ... it has raised A$19.3 million via a placement of ... , the U.S., Asia ... from a share purchase plan (SPP) to be offered ... be made in two tranches. "This capital ...
(Date:7/11/2014)... July 11, 2014 Research and Markets ... the "Immunoprotein Diagnostic Testing Market - Forecasts ... CAGR of 6% and is expected to be ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... testing has been segmented according to immunoprotein types ...
(Date:7/11/2014)... -- Neurelis, Inc. ("Neurelis") today announced an agreement with ... by Biotie to purchase Neurelis, clearing the way for ... for pediatric and adult epilepsy patients who experience acute ... has advanced the development program for NRL-1 and worked ... required for NDA submission to the FDA.  Given the ...
Breaking Medicine Technology:Phosphagenics' A$19.3 million Capital Raising 2Phosphagenics' A$19.3 million Capital Raising 3Immunoprotein Diagnostic Testing Market - Forecasts to 2019: Expected to grow at the highest CAGR of 6% and is expected to be valued at USD 4,943.0 million 2Neurelis Regains Rights to Intranasal Diazepam Program 2Neurelis Regains Rights to Intranasal Diazepam Program 3
... VIVUS, Inc. (Nasdaq: VVUS ) today announced ... Drug Administration (FDA) for the New Drug Application (NDA) for ... meeting occurred on January 19th at the FDA,s offices in ... and VIVUS, management and consultants.  At this meeting the FDA ...
... D. Clark Turner, PhD, President and CEO of Aribex, Inc., ... in a ceremony Tuesday night at Discovery Gateway. Utah Governor ... others for providing distinguished service that has benefited the State ... be recognized among the other accomplished individuals who are receiving ...
Cached Medicine Technology:VIVUS Provides Regulatory Update on QNEXA NDA 2VIVUS Provides Regulatory Update on QNEXA NDA 3Aribex CEO Receives Utah Governor's Medal 2
... the new large power line ... function as both cordless AND ... in flexibility. Its the versatility ... with the security of the ...
... consists of a pistol-grip handpiece available in ... wide range of couplers that can be ... applications., ,MicroAire SmartDriver. Modular Pistol-Grip instrument ... different module for drilling, pinning, cutting, and ...
... Meniscus Implant (CMI) is a type I ... irreparable meniscus tear or loss of meniscus ... procedure. The purpose of the CMI ... and return to a more vigorous lifestyle, ...
... The MicroAire Carpal Tunnel Release System ... surgery. This innovative system, using a minimally-invasive ... small incision at the base of the ... assembly. An endoscope, connected to a standard ...
Medicine Products: