Navigation Links
Bacteria beware: MIT student invents knock-out punch for antibiotic resistance
Date:2/27/2008

. Collins, professor of biomedical engineering at Boston University, Lu developed two bacteriophage platforms to overcome antibiotic resistance. Bacteriophage are viruses that only infect bacteria, not human cells. They have been used since the early 20th century to treat bacterial infections; however, they fell out of favor in the United States due to the advent of antibiotics. Lus work represents an exciting application of synthetic biology, which is an emerging field focused on the rational engineering of organisms to achieve novel functions.

Lu has engineered bacteriophage to boost antibiotic effectiveness. The bacteriophage carries DNA that codes for factors that target bacterial gene networks, which former treatments failed to reach, and destroys bacterial antibiotic resistance mechanisms. The weakened bacterial defenses enable antibiotics to perform better. Administered together, Lus bacteriophage and antibiotics have the potential to eliminate nearly 30,000 times more bacteria than antibiotics alone, including cells that survive antibiotic-only treatment. This combination treatment also thwarts development of stronger antibiotic resistance, which can extend the lifetime of existing and future antibiotic drugs.

While working at a hospital as part of a graduate course, I saw many patients who contracted new infections due to already-compromised immune systems or equipment that is extremely difficult to keep sterile, Lu recalled. Being infected by difficult-to-eradicate bacteria is a traumatic experience for patients and a serious public health issue that needs attention. I thought that there had to be a solution for these infections.

Penetrating Biofilms

Lu also applied his work with bacteriophage to create a new technique for reducing harmful biofilms, which are slimy layers of bacteria that develop on the surfaces of medical, industrial and food processing equipment and are difficult to penetrate and remove. Current t
'/>"/>

Contact: Julie Staadecker
jstaadecker@coneinc.com
617-939-8427
Lemelson-MIT Program
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. Bacterial battle for survival leads to new antibiotic
2. Scientists identify proteins that help bacteria put up a fight
3. Silica smart bombs deliver knock-out to bacteria
4. UCF technique promises to aid doctors ability to identify, treat bacterial infections
5. Why recovery from flu may increase odds of bacterial infection
6. Bacterial toxin closes gate on immune response, Penn researchers discover
7. Barrier Technology Provides New Weapon in MRSA War: Surface Care Products Prevent Growth and Transfer of Bacteria
8. Good bacteria in women give clues for slowing HIV transmission
9. Nerites Receives NIH Grant to Study Novel Treatment for Preventing Dangerous Bacterial Infections on Urinary Stents and Catheters
10. Forsyth launches 1-of-a-kind core service to enable rapid identification of bacterial samples
11. Researchers seek to make cavity-causing bacteria self-destruct
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Bacteria beware: MIT student invents knock-out punch for antibiotic resistance
(Date:5/22/2015)... PA (PRWEB) May 22, 2015 According to ... a hub for drug related death, totaling almost 2,500 confirmed ... as reported by state officials, totals 2,489 deaths stemming from ... work out, Pennsylvania loses seven people every day to fatal ... has been singled out as one of the most rife ...
(Date:5/22/2015)... VA (PRWEB) May 22, 2015 sweetFrog Enterprises, ... location in Jacksonville, Texas. Jacksonville is now the 16th sweetFrog ... yogurt chain was listed as #22 on the Inc. 500 ... “I have lived and worked in East Texas for 20 ... Brad Anderson, owner of the Jacksonville, and nearby Palestine, sweetFrog ...
(Date:5/22/2015)... Ticket Down is a reputable source for authentic ... Conference Finals Tickets . All seating for the 2015 ... ticket listing. , For the first time in some ... the Eastern Conference. One of the original franchises in the ... downs over the years, but the excitement level for this ...
(Date:5/22/2015)... Co founders Greenlee and James Chapko, DDS have launched a ... deliver fully integrated dental implant services to their patients. ... , The Center, whose name is ImplantWide, LLC ... dental implants. These 6 roadblocks can discourage any dentist ... of dental implants into his or her practice. ...
(Date:5/22/2015)... (PRWEB) May 22, 2015 In efforts ... patrons, the section containing particular muscles stretches has been ... nearly 50% of stretches now complete, Chunk Fitness envisions ... planned to be filmed and released at a later ... be found here: http://www.chunkfitness.com/stretches . , About the ...
Breaking Medicine News(10 mins):Health News:Philadelphia Ranks Among the Tops Cities in Penn. for Drug Deaths 2Health News:sweetFrog Opens New Location in Jacksonville, Texas 2Health News:Cheap Lightning vs Rangers NHL Eastern Conference Finals Tickets: Ticket Down Slashes Ticket Prices on New York Rangers vs Tampa Bay Lightning Eastern Conference Playoffs 2Health News:Cheap Lightning vs Rangers NHL Eastern Conference Finals Tickets: Ticket Down Slashes Ticket Prices on New York Rangers vs Tampa Bay Lightning Eastern Conference Playoffs 3Health News:First of Its Kind Dental Implant Training and Surgicenter to Open in June 2
... Skeletal findings suggest men fighting over women took place even ... Men fighting over women? Nothing new there, based on the ... , Durham University-led researchers say that genetic evidence from 34 ... were the result of a tribal war over the need ...
... Md., June 13 The Blinded,American Veterans Foundation (BAVF), ... honor Maryland State Delegate Sheila Hixson., "We,re honored ... residents of Maryland,s District 20 and to the entire ... Spring, MD. "Her,tireless efforts as a legislator and community ...
... Cause of Work Disability in Europe, PARIS, ... treating patients with early, active rheumatoid arthritis (RA),with ... an,indirect cost savings of euro 4,845 (or approximately ... study) per patient per year compared to,MTX treatment ...
... of Mesothelioma Victim Will Address Effort to Find ... Lexi,Miletto, whose grandfather, Joseph Miletto died in 2005 ... the Gala Dinner on Friday,evening, June 27th, part ... Malignant Mesothelioma, which runs Thursday,June 26th through Saturday, ...
... LAUDERDALE, Fla., June 12 Synovics,Pharmaceuticals, Inc., (OTC ... that on June 6, 2008, it formalized,a strategic ... of a joint venture ("JV"). The JV between ... vehicle for Synovics to have access,to assets of ...
... reduction in time awake and a drop in anxiety levels ... moderate aerobic exercise can help reduce anxiety and improve the ... study. Heavy aerobic or moderate strength exercises don,t have the ... Sao Paulo divided 28 women and eight men with primary ...
Cached Medicine News:Health News:Pursuit of Females Dates Way, Way Back 2Health News:Blinded Vets Foundation to Honor Maryland State Delegate Sheila Hixson 2Health News:HUMIRA(R) (adalimumab) Data Show That Treating Early Rheumatoid Arthritis With Combination Treatment Resulted in Cost Savings From Improved Work Productivity 2Health News:HUMIRA(R) (adalimumab) Data Show That Treating Early Rheumatoid Arthritis With Combination Treatment Resulted in Cost Savings From Improved Work Productivity 3Health News:HUMIRA(R) (adalimumab) Data Show That Treating Early Rheumatoid Arthritis With Combination Treatment Resulted in Cost Savings From Improved Work Productivity 4Health News:HUMIRA(R) (adalimumab) Data Show That Treating Early Rheumatoid Arthritis With Combination Treatment Resulted in Cost Savings From Improved Work Productivity 5Health News:HUMIRA(R) (adalimumab) Data Show That Treating Early Rheumatoid Arthritis With Combination Treatment Resulted in Cost Savings From Improved Work Productivity 6Health News:HUMIRA(R) (adalimumab) Data Show That Treating Early Rheumatoid Arthritis With Combination Treatment Resulted in Cost Savings From Improved Work Productivity 7Health News:Asbestos Tragedy and Hope 2Health News:Synovics Pharmaceuticals forms a Strategic Joint Venture with Maneesh Pharmaceuticals 2Health News:Synovics Pharmaceuticals forms a Strategic Joint Venture with Maneesh Pharmaceuticals 3Health News:Synovics Pharmaceuticals forms a Strategic Joint Venture with Maneesh Pharmaceuticals 4Health News:Synovics Pharmaceuticals forms a Strategic Joint Venture with Maneesh Pharmaceuticals 5Health News:Synovics Pharmaceuticals forms a Strategic Joint Venture with Maneesh Pharmaceuticals 6
(Date:5/22/2015)... , May 22, 2015 ... Assay Market by Product (Consumables, Instruments, Services), by Test ... (ELISA, Chromatography, Flow Cytometry), by End Users - Global ... Assays Market is expected to reach $736.85 Million by ... CAGR of 10.25%. Browse 71 market ...
(Date:5/22/2015)... , May 22, 2015   InspireMD, Inc. ... stent embolic protection systems ("EPS"), today announced that its CGuard ... lead by principle investigator Prof. Piotr Musialek , at ... Paris, France . PARADIGM, an ... R cutaneous c A roti D revascularization I ...
(Date:5/22/2015)... Today, Rhodes Pharmaceuticals L.P. announced that Aptensio ... for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) will ... The announcement comes just one month ... Food and Drug Administration (FDA). ... capsule with an onset of effect of 1 ...
Breaking Medicine Technology:Oxidative Stress Assays Market Worth $736.85 Million by 2020 2Oxidative Stress Assays Market Worth $736.85 Million by 2020 3Oxidative Stress Assays Market Worth $736.85 Million by 2020 4InspireMD's CGuardTM Highlighted at Clinical Presentation at EuroPCR 2015 Conference 2InspireMD's CGuardTM Highlighted at Clinical Presentation at EuroPCR 2015 Conference 3InspireMD's CGuardTM Highlighted at Clinical Presentation at EuroPCR 2015 Conference 4Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 2Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 3Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 4Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 5Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 6
... NATICK, Mass., Nov. 25, 2011  RegenoCELL Therapeutics, Inc. (OTCBB: ... is pleased to announce that its wholly owned subsidiary ... with several potential new distributors.  It is anticipated that ... and begin purchasing cell processing services in the near ...
... Biopharmaceutical Company Moleac has announced the launch in France and ... supplement engineered to stimulate neuroplasticity and recovery. NurAiD II is ... operated by Moleac and a growing number of pharmacies across ... to support the restoration of neurological functions: ...
Cached Medicine Technology:Regenocell in Negotiations With Potential New Distributors to Increase Patient Flow 2Regenocell in Negotiations With Potential New Distributors to Increase Patient Flow 3Moleac Announces the Launch of NurAiD II in France, a "Recovery Stimulator" Marketed as a Natural Food Supplement 2Moleac Announces the Launch of NurAiD II in France, a "Recovery Stimulator" Marketed as a Natural Food Supplement 3
Used for emergency airway access when endotracheal intubation cannot be performed. Supplied sterile in peel-open packages. Intended for one-time use....
Used for emergency airway access when conventional endotracheal intubation cannot be performed. Supplied sterile in peel-open packages. Intended for one-time use....
... Standard/Conventional Blade. Stainless steel. Lamp supplied ... tradition of high quality standard incandescent ... blades have been continually refined through ... over to minimize maintenance requirements. They ...
... Snap-Light™ laryngoscope blades are designed with the ... optic bundle can be removed to simplify ... reach areas. Our unique snap-on mechanism eliminates ... focused blades are interchangeable with other green ...
Medicine Products: