Navigation Links
Bacteria From Mouth Can Lead to Heart Inflammation: Study
Date:3/26/2012

MONDAY, March 26 (HealthDay News) -- A type of bacteria from the mouth can cause blood clots and lead to serious heart problems if it enters the bloodstream, a new study indicates.

The bacteria, called Streptococcus gordonii, contributes to plaque that forms on the surface of teeth. If the bacteria enters the bloodstream through bleeding gums, it can cause problems by masquerading as human proteins, the researchers found.

The study authors, from the Royal College of Surgeons in Ireland and the University of Bristol in the United Kingdom, discovered that S. gordonii can produce a molecule on its surface that enables it to mimic the human protein fibrinogen, which is a blood-clotting factor.

This activates platelets (cells that are found in blood and involved in clotting) and causes them to clump inside blood vessels. The resulting blood clots encase the bacteria, protecting the invader from the immune system and from antibiotics used to treat infection.

Platelet clumping can result in growths on the heart valves (endocarditis) or blood vessel inflammation that can block blood supply to the heart or brain.

The findings, to be presented at a Society for General Microbiology meeting in Dublin this week, could help lead to new treatments for infective endocarditis, said study author Dr. Helen Petersen.

"In the development of infective endocarditis, a crucial step is the bacteria sticking to the heart valve and then activating platelets to form a clot," Petersen said in a society news release. "We are now looking at the mechanism behind this sequence of events in the hope that we can develop new drugs which are needed to prevent blood clots and also infective endocarditis."

The researchers stressed that it's important to keep the gums healthy and get regular dental care.

"We are also trying to determine how widespread this phenomenon is by studying other bacteria related to S. gordonii," Petersen said. "What our work clearly shows is how important it is to keep your mouth healthy through regular brushing and flossing, to keep these bacteria in check."

Because this study was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

The U.S. National Heart, Lung, and Blood Institute has more about endocarditis.

-- Robert Preidt

SOURCE: Society for General Microbiology, news release, March 25, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Type of Bacteria May Be Linked to Diabetes
2. Study suggests link between H. pylori bacteria and blood sugar control in adult Type 2 diabetes
3. Solving mystery of how sulfa drugs kill bacteria yields 21st century drug development target
4. Investigators predict, confirm how E. coli bacteria hijack cells directional mechanism
5. In the mouth, smoking zaps healthy bacteria, welcomes pathogens
6. UCI team discovers how protein in teardrops annihilates harmful bacteria
7. VCU study suggests antimicrobial scrubs may reduce bacteria
8. Autism Gastro Problems May Be Linked to Gut Bacteria
9. Dried licorice root fights the bacteria that cause tooth decay and gum disease
10. New evidence that bacteria in large intestine have a role in obesity
11. Jefferson researchers mirror human response to bacterial infection and resolution in mice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/20/2017)... ... 20, 2017 , ... Researchers at the University of Pittsburgh School of Medicine ... that may predict response to a particular class of drugs, not just in patients ... The new findings were published in Proceedings of the National Academy of Science. , ...
(Date:2/20/2017)... ... 2017 , ... The StayWell Company and VUCA Health ... health risks, foster behavior change and improve health literacy among patients. VUCA Health, which ... demonstration of its video capability at StayWell booth 3443 during HiMSS. , The ...
(Date:2/20/2017)... ... February 20, 2017 , ... Sensogram Technologies Inc., the world ... visit this week at HIMSS 2017 Conference & Exhibition. The event brings more ... will be featured in the conference’s Connected Health Experience section, an area specifically ...
(Date:2/20/2017)... ... ... a Population Health Software Company, is pleased to announce a move to a larger office ... the size of the previous location while bringing life back to a medical practice building ... are excited to expand our footprint to better serve our growing client base. We ...
(Date:2/20/2017)... ... February 20, 2017 , ... Johns Hopkins All Children's Hospital ... A topping out ceremony on Friday marked the halfway point of construction and lifting ... in Fall 2018, will serve as a center for innovation aimed at finding new ...
Breaking Medicine News(10 mins):
(Date:2/20/2017)... Feb. 20, 2017  This report analyzes the worldwide markets ... Million. The report provides separate comprehensive analytics for the ... , Europe , ... and Rest of World. Read the ... and forecasts are provided for the period 2015 through ...
(Date:2/20/2017)... Feb. 20, 2017 Research and Markets has ... Insights, Opportunity, Analysis, Market Shares & Forecast 2017 - 2022" ... ... nearly USD 2 Billion by the year end of 2022 growing ... Market growth can be attributed to factors such as ...
(Date:2/20/2017)... -- Seal Shield LLC ( Jacksonville, FL ... management and disinfection, the ElectroClave™, to the exhibit floor ... Orlando, Fla. from February 20-23, 2017 ... commonplace in today,s healthcare landscape, but with this progression ... the disinfection and tracking of these devices.  The ElectroClave™ ...
Breaking Medicine Technology: