Navigation Links
Bacteria From Mouth Can Lead to Heart Inflammation: Study
Date:3/26/2012

MONDAY, March 26 (HealthDay News) -- A type of bacteria from the mouth can cause blood clots and lead to serious heart problems if it enters the bloodstream, a new study indicates.

The bacteria, called Streptococcus gordonii, contributes to plaque that forms on the surface of teeth. If the bacteria enters the bloodstream through bleeding gums, it can cause problems by masquerading as human proteins, the researchers found.

The study authors, from the Royal College of Surgeons in Ireland and the University of Bristol in the United Kingdom, discovered that S. gordonii can produce a molecule on its surface that enables it to mimic the human protein fibrinogen, which is a blood-clotting factor.

This activates platelets (cells that are found in blood and involved in clotting) and causes them to clump inside blood vessels. The resulting blood clots encase the bacteria, protecting the invader from the immune system and from antibiotics used to treat infection.

Platelet clumping can result in growths on the heart valves (endocarditis) or blood vessel inflammation that can block blood supply to the heart or brain.

The findings, to be presented at a Society for General Microbiology meeting in Dublin this week, could help lead to new treatments for infective endocarditis, said study author Dr. Helen Petersen.

"In the development of infective endocarditis, a crucial step is the bacteria sticking to the heart valve and then activating platelets to form a clot," Petersen said in a society news release. "We are now looking at the mechanism behind this sequence of events in the hope that we can develop new drugs which are needed to prevent blood clots and also infective endocarditis."

The researchers stressed that it's important to keep the gums healthy and get regular dental care.

"We are also trying to determine how widespread this phenomenon is by studying other bacteria related to S. gordonii," Petersen said. "What our work clearly shows is how important it is to keep your mouth healthy through regular brushing and flossing, to keep these bacteria in check."

Because this study was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

The U.S. National Heart, Lung, and Blood Institute has more about endocarditis.

-- Robert Preidt

SOURCE: Society for General Microbiology, news release, March 25, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Type of Bacteria May Be Linked to Diabetes
2. Study suggests link between H. pylori bacteria and blood sugar control in adult Type 2 diabetes
3. Solving mystery of how sulfa drugs kill bacteria yields 21st century drug development target
4. Investigators predict, confirm how E. coli bacteria hijack cells directional mechanism
5. In the mouth, smoking zaps healthy bacteria, welcomes pathogens
6. UCI team discovers how protein in teardrops annihilates harmful bacteria
7. VCU study suggests antimicrobial scrubs may reduce bacteria
8. Autism Gastro Problems May Be Linked to Gut Bacteria
9. Dried licorice root fights the bacteria that cause tooth decay and gum disease
10. New evidence that bacteria in large intestine have a role in obesity
11. Jefferson researchers mirror human response to bacterial infection and resolution in mice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... KING OF PRUSSIA, PA (PRWEB) , ... December 07, 2016 , ... ... of clinical trials with the announcement that it is one of the early adopters ... EU-U.S. Privacy Shield Framework is designed to provide companies on both sides of the ...
(Date:12/7/2016)... ... December 07, 2016 , ... "Today, MHA and mental health ... health systems reform legislation in more than fifty years. We applaud the bipartisan ... our elected officials to improving mental health services and supports in our nation. ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... in their bodies, a researcher at the Icahn School of Medicine at Mount ... The study found that when young children are exposed to secondhand marijuana smoke, ...
(Date:12/7/2016)... ... December 07, 2016 , ... Wavelink, an industry leader that ... a new partnership with Splashtop Inc. This remote control for Android extends Wavelink’s ... businesses maximize their uptime and productivity. , Wavelink offers powerful enterprise mobility management ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... acquired Presence Technology, S.L. (“Presence”) for a purchase price of approximately $17.4 ... other considerations. Presence’s annual revenue is approximately $13.2 million. Headquartered in Barcelona, ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... Pa. , Dec. 8, 2016  Pennsylvania ... Secretary of Drug and Alcohol Programs Gary ... and insomnia medications, known as benzodiazepines, developed with ... "Benzodiazepines are medications that are frequently prescribed ... when they are used with opioid pain medications, ...
(Date:12/8/2016)... Information products and services provider Elsevier has launched ... world,s largest abstract and citation database of peer-reviewed literature, providing the ... 5,000 publishers. The new set of metrics will improve decisions on ... adjust a journal,s editorial strategy. ... , CiteScore metrics comprise ...
(Date:12/8/2016)... December 8, 2016 According to the ... Pens Market is expected to be worth US$9.7 bn ... in 2015. Between the forecast years of 2016 and 2024, ... of 7.9%. The leading players operating in the global diabetes ... Company, AstraZaneca plc., Biocon Ltd., and Sanofi S.A. Transparency Market ...
Breaking Medicine Technology: