Navigation Links
Babies Born With Heart Disease Often Harmed by Gut Bacteria
Date:9/1/2011

THURSDAY, Sept. 1 (HealthDay News) -- Elevated blood levels of harmful toxins from gut bacteria occur in about one in five infants and toddlers with congenital heart disease, and the risk is even higher after they have heart surgery, a new study has found.

These endotoxins -- bacterial fragments that cross into the blood from the gut -- stimulate the immune system and can impair the function of vital organs, the study authors explained.

Researchers at Imperial College London in the United Kingdom measured endotoxin levels in 40 children, aged 2 months to 46 months, who required surgery for congenital heart disease.

About 20 percent of the children had higher than normal levels of endotoxin before surgery and that increased to 27.5 percent of the children after surgery, according to the findings published online Aug. 25 in the American Journal of Respiratory and Critical Care Medicine.

The researchers also found that children with high levels of endotoxins in their blood had more signs of organ dysfunction, took longer to recover from surgery, and tended to spend more time in intensive care.

Dr. Nazima Pathan, the lead author of the study from the National Heart and Lung Institute at Imperial College London, said: "The gut usually acts as a barrier that protects the body from toxins. However, our study suggests that in some babies with congenital heart disease, the gut isn't able to do this job properly. These babies are often small and undernourished, and the heart defect can mean that the blood supply to the gut is abnormal."

And, "on top of this they have to cope with the trauma of surgery and our study suggests that all these factors can affect the protective barrier function of the gut," Pathan explained in a college news release.

The researchers said they're now investigating how to protect children with congenital heart disease from these toxins.

More information

The American Heart Association has more about congenital heart defects.

-- Robert Preidt

SOURCE: Imperial College London, news release, Aug. 26, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Mothers Love Can Help Babies With Difficult Temperaments
2. Can oral care for babies prevent future cavities?
3. Prenatal Omega-3 Fatty Acid Supplements May Cut Babies Colds
4. Household smoke increases severity of bronchiolitis in babies
5. Fewer U.S. Teens Having Babies, Binge Drinking: Report
6. Effects of Aspergers syndrome noticeable in babies
7. Helping preterm babies get the best start
8. Too Much Weight Gain in Pregnancy Linked to Chubby Babies
9. Babies May Perform Pure Reasoning, Study Suggests
10. Few Babies in Child-Care Centers Receive Breast Milk: Study
11. Study Questions Giving Babies Botanical Supplements, Teas
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Babies Born With Heart Disease Often Harmed by Gut Bacteria 
(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of Family ... next President and Chief Executive Officer, succeeding Dr. James C. Puffer upon his retirement. ... 1, 2018 until Dr. Puffer’s retirement at the end of 2018. Upon assuming the ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton ... staged a mock evacuation of the facility as part of a disaster drill on ... Echo Hose EMS and Shelton City Emergency Manager, as well as the Connecticut ...
(Date:10/13/2017)... ... , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has ... least understood books in the Holy Scriptures, Revelation. The Book of Revelation paints a ... centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins says that ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare Compliance ... management, will showcase a range of technology and learning solutions at the 68th ... and Expo to be held October 14–18, 2017 at the Mandalay Bay Resort ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics (ACMI) ... FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... Morris F. Collen, a pioneer in the field of medical informatics, this prestigious award ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... -- Halo Labs announces the European launch of their new low ... MIBio 2017 in Cambridge, U.K on October ... biopharmaceutical samples with unprecedented speed and sensitivity while using far less ... Imaging. ... analysis system ...
(Date:9/27/2017)... -- Commended for their devotion to personalized service, SMP Pharmacy Solutions ... in the South Florida Business Journal,s 50 Fastest-Growing Companies, and ... the national specialty pharmacy has found its niche.  To that ... be honored by SFBJ as the 2017 Power Leader in ... receive his award in October, Bardisa said of the three ...
(Date:9/23/2017)... Sept. 22, 2017 Janssen Biotech, Inc. (Janssen) ... letter from the U.S. Food and Drug Administration (FDA) ... sirukumab for the treatment of moderately to severely active ... clinical data are needed to further evaluate the safety ... active RA. ...
Breaking Medicine Technology: