Navigation Links
Babies Born With Heart Disease Often Harmed by Gut Bacteria
Date:9/1/2011

THURSDAY, Sept. 1 (HealthDay News) -- Elevated blood levels of harmful toxins from gut bacteria occur in about one in five infants and toddlers with congenital heart disease, and the risk is even higher after they have heart surgery, a new study has found.

These endotoxins -- bacterial fragments that cross into the blood from the gut -- stimulate the immune system and can impair the function of vital organs, the study authors explained.

Researchers at Imperial College London in the United Kingdom measured endotoxin levels in 40 children, aged 2 months to 46 months, who required surgery for congenital heart disease.

About 20 percent of the children had higher than normal levels of endotoxin before surgery and that increased to 27.5 percent of the children after surgery, according to the findings published online Aug. 25 in the American Journal of Respiratory and Critical Care Medicine.

The researchers also found that children with high levels of endotoxins in their blood had more signs of organ dysfunction, took longer to recover from surgery, and tended to spend more time in intensive care.

Dr. Nazima Pathan, the lead author of the study from the National Heart and Lung Institute at Imperial College London, said: "The gut usually acts as a barrier that protects the body from toxins. However, our study suggests that in some babies with congenital heart disease, the gut isn't able to do this job properly. These babies are often small and undernourished, and the heart defect can mean that the blood supply to the gut is abnormal."

And, "on top of this they have to cope with the trauma of surgery and our study suggests that all these factors can affect the protective barrier function of the gut," Pathan explained in a college news release.

The researchers said they're now investigating how to protect children with congenital heart disease from these toxins.

More information

The American Heart Association has more about congenital heart defects.

-- Robert Preidt

SOURCE: Imperial College London, news release, Aug. 26, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Mothers Love Can Help Babies With Difficult Temperaments
2. Can oral care for babies prevent future cavities?
3. Prenatal Omega-3 Fatty Acid Supplements May Cut Babies Colds
4. Household smoke increases severity of bronchiolitis in babies
5. Fewer U.S. Teens Having Babies, Binge Drinking: Report
6. Effects of Aspergers syndrome noticeable in babies
7. Helping preterm babies get the best start
8. Too Much Weight Gain in Pregnancy Linked to Chubby Babies
9. Babies May Perform Pure Reasoning, Study Suggests
10. Few Babies in Child-Care Centers Receive Breast Milk: Study
11. Study Questions Giving Babies Botanical Supplements, Teas
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Babies Born With Heart Disease Often Harmed by Gut Bacteria 
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, ... the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, where ... city’s history as home to some of the world’s leading providers of cereal and ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American ... Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. ... including advance care planning, healthcare costs and patient and family engagement. , AIR ...
(Date:6/25/2016)... CA (PRWEB) , ... June 25, 2016 , ... As ... with Magna Cum Laude and his M.D from the David Geffen School of Medicine ... and returned to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Those who ... with these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, ... Marne, Michigan, has released tools for healthy coping following a traumatic event. , Trauma ...
(Date:6/24/2016)... ... 24, 2016 , ... Dr. Amanda Cheng, an orthodontist ... has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be used ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Bracket , a leading clinical trial ... clinical outcomes platform, Bracket eCOA (SM) 6.0, at the ... – 30, 2016 in Philadelphia , Pennsylvania.  ... Assessment product of its kind to fully integrate with RTSM, ... eCOA 6.0 is a flexible platform for electronic clinical outcomes ...
(Date:6/23/2016)... Ill. and BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment ... Astellas Farma Brasil as the company,s second affiliate in Latin America . ... ... General Manager of Astellas Farma Colombia ... ...
(Date:6/23/2016)... The vast majority of dialysis patients currently ... are usually 3 times a week, with treatment times ... time, equipment preparation and wait time.  This regimen can ... patients who are elderly and frail.  Many elderly dialysis ... centers for some duration of time. Residents ...
Breaking Medicine Technology: