Navigation Links
Babies Born With Heart Disease Often Harmed by Gut Bacteria

THURSDAY, Sept. 1 (HealthDay News) -- Elevated blood levels of harmful toxins from gut bacteria occur in about one in five infants and toddlers with congenital heart disease, and the risk is even higher after they have heart surgery, a new study has found.

These endotoxins -- bacterial fragments that cross into the blood from the gut -- stimulate the immune system and can impair the function of vital organs, the study authors explained.

Researchers at Imperial College London in the United Kingdom measured endotoxin levels in 40 children, aged 2 months to 46 months, who required surgery for congenital heart disease.

About 20 percent of the children had higher than normal levels of endotoxin before surgery and that increased to 27.5 percent of the children after surgery, according to the findings published online Aug. 25 in the American Journal of Respiratory and Critical Care Medicine.

The researchers also found that children with high levels of endotoxins in their blood had more signs of organ dysfunction, took longer to recover from surgery, and tended to spend more time in intensive care.

Dr. Nazima Pathan, the lead author of the study from the National Heart and Lung Institute at Imperial College London, said: "The gut usually acts as a barrier that protects the body from toxins. However, our study suggests that in some babies with congenital heart disease, the gut isn't able to do this job properly. These babies are often small and undernourished, and the heart defect can mean that the blood supply to the gut is abnormal."

And, "on top of this they have to cope with the trauma of surgery and our study suggests that all these factors can affect the protective barrier function of the gut," Pathan explained in a college news release.

The researchers said they're now investigating how to protect children with congenital heart disease from these toxins.

More information

The American Heart Association has more about congenital heart defects.

-- Robert Preidt

SOURCE: Imperial College London, news release, Aug. 26, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Mothers Love Can Help Babies With Difficult Temperaments
2. Can oral care for babies prevent future cavities?
3. Prenatal Omega-3 Fatty Acid Supplements May Cut Babies Colds
4. Household smoke increases severity of bronchiolitis in babies
5. Fewer U.S. Teens Having Babies, Binge Drinking: Report
6. Effects of Aspergers syndrome noticeable in babies
7. Helping preterm babies get the best start
8. Too Much Weight Gain in Pregnancy Linked to Chubby Babies
9. Babies May Perform Pure Reasoning, Study Suggests
10. Few Babies in Child-Care Centers Receive Breast Milk: Study
11. Study Questions Giving Babies Botanical Supplements, Teas
Post Your Comments:
Related Image:
Babies Born With Heart Disease Often Harmed by Gut Bacteria 
(Date:6/27/2016)... ... , ... recently awarded their highest five-star rating to Best Buy Eyeglasses, ... the United States and Canada wear eyeglasses. Once considered to be a purely functional ... a fashion statement. Even celebrities use glasses as a way of creating an iconic ...
(Date:6/26/2016)... , ... June 26, 2016 , ... PawPaws brand ... new product that was developed to enhance the health of felines. The formula is ... The two main herbs in the PawPaws Cat Kidney Support Supplement Soft ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, ... Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. ... skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was ...
(Date:6/25/2016)... ... ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors in ... School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green Hospital ... at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train in ...
(Date:6/24/2016)... Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... surgery procedures that most people are unfamiliar with. The article goes on to state ... procedures, but also many of these less common operations such as calf and cheek ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Research and Markets has announced the addition ... - Forecast to 2022" report to their offering. ... to date financial data derived from varied research sources to ... potential impact on the market during the next five years, ... of sub markets, regional and country level analysis. The report ...
(Date:6/23/2016)... , June 23, 2016 , ... on Thursday, July 7, 2016 , , , , LOCATION: ... , , , , EXPERT PANELISTS:  , , , ... Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and ... The global pharmaceutical industry is witnessing an exceptional era. ...
(Date:6/23/2016)... , June 23, 2016  Guerbet announced today ... Inc.,s Supplier Horizon Award . One ... Guerbet was recognized for its support of Premier members ... through clinical excellence, and commitment to lower costs. ... receive this recognition of our outstanding customer service from ...
Breaking Medicine Technology: