Navigation Links
BUSPH researchers link widely used chemicals to ADHD in children
Date:7/20/2010

A new study led by a team of Boston University School of Public Health researchers suggests a link between polyfluoroalkyl chemicals (PFCs), industrial compounds which are widely used in many consumer products, and attention deficit hyperactivity disorder (ADHD) in children.

Published online, ahead of print, in the journal Environmental Health Perspectives, the researchers found "increased odds of ADHD in children with higher serum PFC levels." The researchers used data from the National Health and Nutrition Examination Survey (NHANES) to compare the PFC levels found in serum samples taken from 571 children, ages 12 to 15. The parents of 48 of these children reported their children were diagnosed with ADHD, one of the most common neurodevelopmental disorders in children.

NHANES is an ongoing national survey of a representative sample of the U.S. population that gathers data on dietary and health factors conducted by the Centers for Disease Control and Prevention.

PFCs are highly stable compounds used in industrial and commercial products like stain-resistance coatings, food packaging, and fire-fighting foams. In a 2003-2004 survey, NHANES examined 2,094 blood samples taken from the U.S. population and found more than 98 percent of the sample had detectable serum levels of PFCs, according to the study. Once absorbed into the body, it can take years for some types of PFCs to be partially eliminated.

Although the study indicates there is a link between PFCs and ADHD, lead author Kate Hoffman said it is not known if there is a causal relationship between the two.

"There's a link between this exposure and outcome but we're not really sure what way that goes," said Hoffman, PhD, who conducted the study while completing her doctorate in environmental health at BUSPH. "What we can say is children with this outcome tend to have higher levels of PFCs in their blood." Because the PFC measurements were collected at the same time as the parental report of ADHD diagnosis, Hoffman said it is unknown whether children with ADHD engage in behavior leading to increased PFC exposure or if higher serum PFC levels in children result in ADHD.

The researchers examined the connection between four PFCs, perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA), and perfluorohexane sulfonic acid (PFHxS) and samples from children in which there were parental reports of ADHD diagnosis.

The authors focused on ADHD because studies on animals have suggested exposure to PFCs can have neurotoxic effects. There is little information, however, on the chemicals' effects on human development.

ADHD is one of the most common neurodevelopmental disorders, Hoffman said. It is also unknown what causes ADHD, she said, but genetic and environmental factors have been associated with the disorder.

"Given the extremely prevalent exposure to PFCs, further investigation into the impact of PFC exposure on ADHD and other neurodevelopmental endpoints is warranted," the authors wrote.


'/>"/>

Contact: Elana Zak
ezak@bu.edu
617-414-1401
Boston University Medical Center
Source:Eurekalert

Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Researchers discover new way to kill pediatric brain tumors
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Researchers create drug to keep tumor growth switched off
6. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
7. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
8. Clemson researchers develop hands-free texting application
9. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
10. Researchers chart genomic map spanning over 2 dozen cancers
11. Researchers discover second protective role for tumor-suppressor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/7/2016)... ... February 07, 2016 , ... ... empowers employers and organizations with the tools and information to lower the costs, ... to cut the cost of providing employee healthcare benefits by as much as ...
(Date:2/6/2016)... ... February 06, 2016 , ... US Sports Camps is proud to sponsor ... event brings together top non-profit leaders, ultimate organizations, and coaches from around the US. ... Bay Area Disc Program Director of Youth and Education, describes this year YUCC as ...
(Date:2/6/2016)... Pekin, IL (PRWEB) , ... February 06, 2016 ... ... the recovery phases of eating disorder treatment helps to reduce the frequency and ... “Tasks of the Recovery Phase: Re-Establishing Healthy Identity and Purpose,” will explore the ...
(Date:2/5/2016)... ... February 05, 2016 , ... VeloReality ... lighter, sleeker next generation LYNX VR Indoor Trainer with multi-rider capability to an ... and manufacturing not only reduce the weight of the unit, they also enhance ...
(Date:2/5/2016)... ... 2016 , ... The event is being held on April 7, 2016 from ... Triumph Over Parkinson’s will fund nearly $100,000 for research for the care and cure ... disease and is the architect of this informative event to raise awareness and funds ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... 2016 Aethlon Medical, Inc. (Nasdaq: AEMD ), ... will be presenting at Source Capital Group,s 2016 Disruptive Growth ... at 2:15 p.m. ET on Wednesday, February 10, 2016.  ... taking place at 3:15 p.m. ET. http://www.aethlonmedical.com .  ... after the conclusion of the live event. The panel discussion ...
(Date:2/5/2016)... , February 5, 2016 ... market research report "Fetal (Labor & Delivery) and Neonatal ... Warmer, Incubator, Pulse Oximeter, Phototherapy/Jaundice Management Devices, CPAP, Capnograph, ... MarketsandMarkets, This report studies the global market over the ... estimated at USD 6.28 Billion in 2015 and is ...
(Date:2/4/2016)... Feb. 4, 2016 For hospitals considering enrollment ... already participating in the program, the Health Resources and ... as the , Mega-Guidance , could have significant impact ... published in September 2016. Essential Insights , ... Marketing , summarizes the Mega-Guidance,s key proposed changes, including ...
Breaking Medicine Technology: