(Boston) A study conducted by researchers at Boston University School of Medicine (BUSM) shows that magnetic resonance imaging (MRI) detected a high prevalence of abnormalities associated with knee osteoarthritis in middle-aged and elderly patients that had no evidence of knee osteoarthritis in X-ray images.
Ali Guermazi, MD, PhD, professor of radiology at BUSM and chief of Musculoskeletal Imaging at Boston Medical Center (BMC), led this study in collaboration with researchers from Lund University in Sweden, Brigham and Women's Hospital in Boston and Klinikum Augsburg in Germany. The findings are published online in BMJ.
Osteoarthritis, the most common form of arthritis, is characterized by a degeneration of cartilage and the underlying bone and other soft tissues in the joints, leading to pain and stiffness. According to the Centers for Disease Control and Prevention, osteoarthritis is the leading cause of disability in the United States, affecting approximately 26.9 million Americans. It is responsible for a significant portion of primary care visit and hospitalizations and has a large financial impact on health care. With the aging population, it is anticipated that the prevalence of osteoarthritis will continue to increase.
Prior studies have shown that only half of those with knee pain will have X-ray evidence of osteoarthritis. This study looked at how to further evaluate a patient's knee pain if X-rays don't show evidence of osteoarthritis. It also looked at whether MRI, in these cases, is of clinical value.
This observational study looked at the prevalence of MRI-detected abnormalities in a group of adults over the age of 50 who had no signs of knee osteoarthritis in X-ray images. The researchers looked at right knee MRIs of 710 ambulatory patients from the Framingham Osteoarthritis Study. Further analysis was performed on groups by age, gender, body mass index and the presence or absence of knee pain.
|Contact: Jenny Eriksen|
Boston University Medical Center