Navigation Links
BUSM researchers study use of MRI in osteoarthritis
Date:8/31/2012

(Boston) A study conducted by researchers at Boston University School of Medicine (BUSM) shows that magnetic resonance imaging (MRI) detected a high prevalence of abnormalities associated with knee osteoarthritis in middle-aged and elderly patients that had no evidence of knee osteoarthritis in X-ray images.

Ali Guermazi, MD, PhD, professor of radiology at BUSM and chief of Musculoskeletal Imaging at Boston Medical Center (BMC), led this study in collaboration with researchers from Lund University in Sweden, Brigham and Women's Hospital in Boston and Klinikum Augsburg in Germany. The findings are published online in BMJ.

Osteoarthritis, the most common form of arthritis, is characterized by a degeneration of cartilage and the underlying bone and other soft tissues in the joints, leading to pain and stiffness. According to the Centers for Disease Control and Prevention, osteoarthritis is the leading cause of disability in the United States, affecting approximately 26.9 million Americans. It is responsible for a significant portion of primary care visit and hospitalizations and has a large financial impact on health care. With the aging population, it is anticipated that the prevalence of osteoarthritis will continue to increase.

Prior studies have shown that only half of those with knee pain will have X-ray evidence of osteoarthritis. This study looked at how to further evaluate a patient's knee pain if X-rays don't show evidence of osteoarthritis. It also looked at whether MRI, in these cases, is of clinical value.

This observational study looked at the prevalence of MRI-detected abnormalities in a group of adults over the age of 50 who had no signs of knee osteoarthritis in X-ray images. The researchers looked at right knee MRIs of 710 ambulatory patients from the Framingham Osteoarthritis Study. Further analysis was performed on groups by age, gender, body mass index and the presence or absence of knee pain.

The results showed that approximately 90 percent of the knees that showed no signs of osteoarthritis using X-ray showed clear signs of osteoarthritis using MRI. In addition, MRI abnormalities were highly prevalent even in persons whose knees were not painful, suggesting that MRI was not a useful diagnostic test in this age group to evaluate knee pain.

"This data demonstrates a very high prevalence of MRI-detected osteoarthritis features in knees with no X-ray evidence of the disease," said Guermazi. "While the MRI could be detecting early-stage osteoarthritis, further research is needed to determine what proportion of these individuals are diagnosed with knee osteoarthritis later in life."

The researchers mention that MRI would be too expensive to perform as a routine imaging investigation.


'/>"/>

Contact: Jenny Eriksen
jenny.eriksen@bmc.org
617-638-6841
Boston University Medical Center
Source:Eurekalert

Related medicine news :

1. Wayne State researchers say adolescent smoking prevention programs still critical
2. WSU researchers discover mechanism leading from trichomoniasis to prostate cancer
3. URMC researchers connect new genetic signature to leukemia
4. Trudeau researchers identify unforeseen regulation of the anti-bacterial immune response
5. In war with superbugs, Cedars-Sinai researchers see new weapon: Immune-boosting vitamin
6. Midlife fitness staves off chronic disease at end of life, UT Southwestern researchers report
7. Moffitt Cancer Center researchers and colleagues identify PHF20, a regulator of gene P53
8. Cramming for a test? Dont do it, say UCLA researchers
9. Brigham and Womens Hospital researchers initiate major cardiovascular inflammation reduction trial
10. Johns Hopkins researchers return blood cells to stem cell state
11. Researchers highlight treatment, research needs for homeless families
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... ... , ... The Dawn Johnson Insurance Group, a Missouri-based insurance and financial planning ... support for efforts to educate the local population on cancer realities while attracting donations ... , Each day in America, roughly 4,600 new cases of cancer are diagnosed ...
(Date:8/18/2017)... The Woodlands, TX (PRWEB) , ... August 18, ... ... asset protection assistance and financial planning services to communities in east Texas, is ... the Pediatric Brain Tumor Foundation. , Founded in 1991, the Pediatric Brain Tumor ...
(Date:8/18/2017)... ... August 18, 2017 , ... Goss & Associates ... residential and commercial clients in the greater Houston region, is helping locally recognized ... the fight against cancer. , Founded by Tony and Amber Bender after losing ...
(Date:8/18/2017)... Boca Raton, Fl (PRWEB) , ... August 18, ... ... nation’s largest network of highly trained practitioners specializing in bioidentical hormone replacement therapy ... symptoms associated with hormone imbalance and conditions of aging, such as menopause, andropause, ...
(Date:8/18/2017)... IN (PRWEB) , ... August 18, 2017 , ... Inc. ... annual list, the most prestigious ranking of the nation's fastest-growing private companies. This marks ... the exclusive Inc. 5000 ranking . This year’s ranking reflects ASH’s 76 percent ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... Aug. 7, 2017 Zimmer Biomet Holdings, Inc. (NYSE ... announced that its Board of Directors has approved the payment ... quarter of 2017. The ... or about October 27, 2017 to stockholders of record as ... declarations of dividends are subject to approval of the Board ...
(Date:8/4/2017)... Md. , Aug. 4, 2017 The ... or shortly after a physician/patient consult has long been ... and was a notable focus of the largest meeting ... is according to healthcare market research firm Kalorama Information. ... care testing (POCT) offerings or related supplies and software ...
(Date:8/2/2017)... 2017   Marshall County Hospital in Benton, Kentucky has ... of hospital-acquired infections (HAIs). The new addition, Tru-D SmartUVC , short for "total room ... pathogens such as C. diff , MRSA, MERS, Ebola and more. ... Tru-D SmartUVC ... Tru-D in action in a patient room ...
Breaking Medicine Technology: