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BUSM researchers involved in first international collaboration on genetics of Alzheimer's disease
Date:2/1/2011

Feb. 1, 2011, Boston - The launch of the International Genomics of Alzheimer's Project (IGAP) a collaboration formed to discover and map the genes that contribute to Alzheimer's disease was announced today by a multi-national group of researchers including Drs. Lindsay Farrer and Sudha Seshadri at Boston University School of Medicine (BUSM). The collaborative effort, spanning universities from both sides of the Atlantic, will combine the knowledge, staff and resources of four consortia that work on Alzheimer's disease genetics.

The four groups are:

  • The European Alzheimer's Disease Initiative (EADI) in France led by Philippe Amouyel, M.D., Ph.D., at the Institute Pasteur de Lille and Lille University.
  • The Alzheimer's Disease Genetics Consortium (ADGC) from the United States led by Gerard Schellenberg, Ph.D., at the University of Pennsylvania School of Medicine.
  • The Genetic and Environmental Risk in Alzheimer's Disease (GERAD) from the United Kingdom led by Julie Williams, Ph.D., at Cardiff University.
  • The neurology subgroup of the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) led by Sudha Seshadri, M.D., at BUSM.

One of the research teams at BUSM, directed by Lindsay Farrer, PhD, a professor and chief of biomedical genetics at BUSM, is co-leading the primary analyses for IGAP on behalf of the Alzheimer's Disease Genetic Consortium (ADGC), which includes investigators from 44 different universities and research institutions across North America. The researchers will analyze detailed clinical information and genetic profiles obtained from more than 40,000 Alzheimer cases and cognitively normal persons. Other researchers from Boston University involved in this effort are Drs. Gyungah Jun and Kathryn Lunetta.

"Identification of genes that contribute to Alzheimer's risk and that influence the progression of disease will help lead us to the cause of the disease, identify proteins
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Contact: Jenny Eriksen Leary
jenny.eriksen@bmc.org
617-638-6841
Boston University Medical Center
Source:Eurekalert

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