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BUSM researchers find no adjustment method fully resolves confounding by indication
Date:5/26/2009

h cancer, non-randomized studies are vitally important," said lead author Jaclyn Bosco, MPH, project director in the Section of Geriatrics at BUSM. "Non-randomized studies are only reliable when confounding by indication is handled adequately. When treatment with adjuvant chemotherapy among older patients is based on clinical judgment, controlling for prognostic factors alone leaves residual confounding by indication."

Researchers further stated that PS and IV analysis methods can be useful under specific situations, but neither method adequately controlled confounding by indication in this study.


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Contact: Michelle Roberts
michelle.roberts@bmc.org
617-638-8491
Boston University Medical Center
Source:Eurekalert

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