Navigation Links
BUSM researchers find gram-negative rods in two Philippine neonatal intensive care units

(Boston) - Researchers at Boston University School of Medicine (BUSM) have found a high frequency of multidrug-resistant Gram-negative rods (GNRs) in two of the largest neonatal intensive care units (NICUs) in the city of Manila, Philippines. Improved infection control methods could reduce the vast number of hospital acquired neonatal infections. The BUSM study appears online in the journal Infection Control and Hospital Epidemiology.

According to researchers, hospital acquired infections have emerged as a significant health problem in developing areas. Neonatal mortality accounts for more than one third of all global child deaths each year. Sepsis is a leading cause of death within the first month of life and is often acquired through unhygienic care practices in healthcare facilities, which frequently have limited emphasis placed on standard infection control measures.

Over a 10-month period, BUSM researchers conducted studies for colonization and bloodstream infections with gentamicin or third generation cephalosporin-resistant GNR among all NICU infants weekly and then on the day of discharge. Researchers found a total of 1,997 resistant GNRs colonizing 1,831 neonates. Results also showed that 376 newborns became bacteremic with a total of 437 GNRs.

The most common GNR species identified were Klebsiella, Acinetobacter, Pseudomonas aeruginosa and Enterobacter. A high proportion of colonization and bacteremia at the two NICUs was with non-intestinal GNRs. Factors significantly associated with increased risk of bacteremia were mechanical ventilation and prematurity. Additionally, colonization with a resistant GNR was an independent risk factor for bacteremia.

"Colonization with a resistant GNR was an independent risk factor for sepsis," said senior author, Davidson Hamer, MD, associate professor of international health and medicine at Boston University School of Public Health, and director of Boston Medical Center's Travel Clinic. "The unusually high intensity of colonization pressure and disease with multidrug-resistant GNRs at these two NICUs constitutes an emerging health care crisis in the developing world."


Contact: Michelle Roberts
Boston University Medical Center

Related medicine news :

1. Mayo Clinic researchers say agent provides treatment option for women with hot flashes
2. Researchers identify key proteins needed for ovulation
3. Participants in antidepressant drug trials are atypical patients, UT Southwestern researchers report
4. Researchers study the human factor in spread of pandemic illness
5. Body movements can influence problem solving, researchers report
6. Researchers identify the gene responsible for a rare form of congenital anemia
7. K-State Researchers and Their Partners Making it Easier for Rural Kansans of All Ages to Stay Healthy Despite Limited Access to Facilities Like Bike Trails, Gyms
8. IBM and Medical Researchers Launch Effort To Find Flu Drug Treatments
9. Children with concussions require follow-up care before returning to play, say researchers
10. Children with Concussions Require Follow-up Care Before Returning to Play, Say Researchers
11. Cancer-obesity link discovery by MSU researchers could aid prevention efforts
Post Your Comments:
(Date:12/1/2015)... ... December 01, 2015 , ... ... for the care management and population health arenas, is pleased to announce that ... cost containment services, has successfully implemented the ACUITY Complete Care™ Management to back ...
(Date:12/1/2015)... ... 2015 , ... With FCPX Overlay: Grit , users can apply a ... possibilities are truly endless, all with a click of a mouse. Each user has ... flip, depth of field and more, all within Final Cut Pro X. , With ...
(Date:12/1/2015)... ... December 01, 2015 , ... Tympani ... Technology Provider (ATP) status from Cisco. This designation recognizes Tympani as having fulfilled ... Contact Center solutions targeted to the high-end enterprise contact center marketplace. , Ed ...
(Date:11/30/2015)... ... December 01, 2015 , ... The Turks & Caicos Islands has enjoyed being ... news sites highlighting Caribbean destinations, has published five reasons to visit the Turks & ... shivers under chilly grey skies or worse, it's typically a balmy 80 degrees in ...
(Date:11/30/2015)... ... November 30, 2015 , ... 1Heart Caregiver Services’ ... the Federation of Philippine American Chambers of Commerce held from November 6-8, 2015 ... 1Heart Caregiver Services, as an active delegate from the Philippine American Chamber of ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... , November 30, 2015 ... --> adds a 2015 ... 2010 - 2015 with comprehensive analysis ... range of deal types, such as ... alliances. . ...
(Date:11/30/2015)... , Nov. 30, 2015  Kevin Smith has ... Healthcare, a global pioneer in wireless monitoring of ... Boston, MA , Mr. Smith will be ... global commercial strategy.  He will also directly oversee ... build clinical evidence for SensiumVitals, the first early ...
(Date:11/30/2015)... , Nov. 30, 2015  The ... norm in U.S. medical imaging is on ... popular accountable care payer-provider contracts are set ... in their wake, alter provider-vendor relationships. The ... will push forward new purchasing frameworks in ...
Breaking Medicine Technology: