Navigation Links
BPA alters development of in vitro ova and could increase risk of Down syndrome
Date:9/21/2011

Researchers at Universitat Autnoma de Barcelona, in collaboration with the Vall d'Hebron Hospital Fetal Tissue Bank, the Department of Gynaecology and the Research Unit of Paediatric Endocrinology, analysed the effects of Bisphenol A (BPA), a polymer widely used to manufacture plastics, in an in vitro culture of ovaries. The research demonstrated that exposure to this substance gravely altered the development of oocytes and future ova, possibly diminishing the fertility of a woman's offspring and at the same time increasing the risk of Down Syndrome in following generations.

The research, published in Human Reproduction, was carried out with a culture of 21,570 in vitro oocytes. Results demonstrated that exposure to Bisphenol A in concentration levels permitted by health authorities is harmful to the fetus. BPA reduces the number of oocytes (cells which develop into ova) and therefore can affect negatively a woman's fertility and double the risk of chromosome exchange during the cell division process. Specific observations of chromosome 21 in the development of 90 oocytes revealed that exposure to BPA could increase the risk of Down Syndrome in the future offspring of the fetus.

The research provides conclusive data for the debate on how BPA affects the health of individuals. Previous studies on mice and worms demonstrated that reproduction is affected and that exposure to BPA during gestation affects the viability and quality of the cells which later become ova developing in the fetus.

For the first time, human cells were used in a research to analyse the process of cell division of the oocytes - meiosis - in which chromosomes join and exchange material, i.e. meiotic recombination. Oocytes were cultured for 7, 14 or 21 days in different environments, with the presence of BPA and in control cultures without the substance. Data obtained in vitro with human cells was practically identical to that obtained with in vivo animal
'/>"/>

Contact: Montserrat Garcia Caldes
Montserrat.garcia.caldes@uab.cat
34-935-811-905
Universitat Autonoma de Barcelona
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Air pollution alters immune function, worsens asthma symptoms
2. IU researchers: Chemotherapy alters brain tissue in breast cancer patients
3. A high-fat diet alters crucial aspects of brain dopamine signaling
4. Barbara Walters Prognosis Is Excellent, Doctors Say
5. Using new approach, Mayo Clinic researchers find level of gene alters risk of Alzheimers disease
6. NIDA Avant-Garde-Medications Development Award winners announced
7. Transformative NIH grant will support development of tissue regeneration therapeutics
8. New strategy likely to speed drug development for rare cancers
9. Prenatal exposure to phthalates linked to decreased mental and motor development
10. Memory Development Incomplete Until Adulthood: Study
11. Researchers developing new test to measure risk for birth defects and neuro-developmental disorders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... Recently, Top10BestSEOHosting.com has compared many professional SEO ... one of the most reliable suppliers for webmasters who ... been a boom in websites in recent years, and ... the number of web hosting companies that offer a ... HostMonster has been providing hosting solutions to thousands of ...
(Date:8/21/2014)... Recently, Skmen.com, a distinguished garment supplier, has updated ... girls’ casual dresses . From today until August 31, all ... off) when they are shopping at the company’s online store. ... according to the newest quality standards; they are guaranteed to ... dresses, worldwide ladies can also access the other cheap items ...
(Date:8/21/2014)... Lake City, Utah (PRWEB) August 21, 2014 ... ) is pleased to announce the addition of ... over 30 years of healthcare management experience, Gillespie ... His experience includes multiple executive management positions with ... Most recently Kerry served as President of Triad ...
(Date:8/21/2014)... (PRWEB) August 22, 2014 Top10BestSEOHosting.com ... and announces that iPage ( http://www.top10bestseohosting.com/go/iPage/ ) is ... in 2014. , The manager of Top10BestSEOHosting.com ... cheap hosting supplier. Actually, these companies have outperformed ... and customer support. People can get the best ...
(Date:8/21/2014)... Fayetteville, Georgia (PRWEB) August 21, 2014 ... amenities and the atmosphere that comes along with it. ... Fayetteville makes sure that such amenities are available. ... lifestyle community in Fayetteville, Georgia and Community Association Management, ... structure from American Parks Company to provide an additional ...
Breaking Medicine News(10 mins):Health News:Best SEO Hosting Suppliers in the Global Market Recommended by Top10BestSEOHosting.com 2Health News:Charming Girls’ Casual Dresses Now Released by Distinguished Garment Company Skmen.com 2Health News:Kerry Gillespie Appointed as Chief Executive Officer of AVEC Health Solutions 2Health News:iPage Reviews Unveiled Online At Top10BestSEOHosting.com 2Health News:Recreation is the Heart of the Community at Simpson Mill Plantation; Chooses American Parks Company™ for New Playground Equipment 2Health News:Recreation is the Heart of the Community at Simpson Mill Plantation; Chooses American Parks Company™ for New Playground Equipment 3
... , MONDAY, Jan. 3 (HealthDay News) People ... of becoming obese, new study findings show. Researchers at ... from two large U.S. alcoholism surveys conducted in 1991-1992 and ... women with a family history of alcoholism were 49 percent ...
... the U.S has seen a sharp increase in the number ... weeks, gestation. This is approximately 400,000 children each year, comprising ... are treated the same as full-term infants since they are ... that this can be detrimental to a late-preterm infant,s health ...
... Chronic Total Occlusion Summit and Left Main Coronary ... technologies, research findings and new developments in therapeutic ... in chronic total coronary occlusions and left main ... include:, When and why to open a ...
... chemical group to it at a specific site, a protein ... international research team led by scientists at The University of ... of Nature Cell Biology . In addition to ... same deactivation of the enzyme called EZH2 is necessary for ...
... 2011 For the first time, universal standards to ... medication labels to reflect how patients read and understand ... These labels can vary significantly from pharmacy to pharmacy, ... for the safe use of medications. The new standards, ...
... Philadelphia, PA, January 3, 2011 Postoperative adhesions are ... been used in the hopes of preventing these adhesions ... article in the December 2010 issue of the ... American Association of Pediatric Ophthalmology and Strabismus, a team ...
Cached Medicine News:Health News:Family History of Alcoholism May Raise Obesity Risk 2Health News:Care of late-preterm preemies may be insufficient 2Health News:Care of late-preterm preemies may be insufficient 3Health News:Protein wields phosphate group to inhibit cancer metastasis 2Health News:Universal standards proposed for prescription container labels to help reduce medication misuse 2Health News:Universal standards proposed for prescription container labels to help reduce medication misuse 3Health News:Use of amniotic membrane may cause complications in strabismus surgery 2
(Date:8/21/2014)... 21, 2014  Publicis Groupe customer engagement agency ... Partner and Healthcare Industry Group Leader, has been featured ... the most inspiring people in the life-sciences industry. Those ... and development, marketing, technology, creativity, strategy and medicine. ... a partner in its leading Rosetta Consulting practice. In ...
(Date:8/21/2014)... BURLINGTON, Mass. , Aug. 21, 2014 /PRNewswire/ ... of COPD,  physicians in Brazil ... to follow clinical guidelines and commonly prescribe long-acting ... regimens, although they do so within current severe ... combinations (FDCs) that are expected to launch in ...
(Date:8/21/2014)... 2014 /PRNewswire-iReach/ -- ScriptPro has been certified by ... Common Security Framework (CSF). According to Russ ... "We appreciate this rigorous, top-to-bottom audit. Security-minded customers ... certification signifies. Our business partners need to know ... CERTIFICATION PROCESS: ScriptPro,s internal security processes and controls ...
Breaking Medicine Technology:Shannon Hartley Shines in PharmaVOICE 100 2Novel Fixed-Dose Combinations for COPD in Brazil and Mexico Will Compete With Well-Established Therapies in an Environment Dominated by Aggressive Cost-Control Mechanisms 2Novel Fixed-Dose Combinations for COPD in Brazil and Mexico Will Compete With Well-Established Therapies in an Environment Dominated by Aggressive Cost-Control Mechanisms 3ScriptPro Achieves HITRUST Certification 2
... , , INDIANAPOLIS, Nov. 16 AMD ... laser technology, today announced the addition of Bart Waclawik ... Mr. Waclawik will be responsible for daily global operations, ... the company. Furthermore, he will lead the engineering effort ...
... Nov. 16 Despite the recession, overall growth ... 15 percent in the past two years, according to a ... Solutions. Retail clinic market growth, however, will likely slow to ... 30 percent from 2013-2014, according to the report. , ...
Cached Medicine Technology:AMD LASERS Announces the Addition of Bart Waclawik, New Chief Operating Officer 2Health Care Retail Clinics Continue Gradual Expansion Through 2012: Deloitte Center for Health Solutions Report 2Health Care Retail Clinics Continue Gradual Expansion Through 2012: Deloitte Center for Health Solutions Report 3Health Care Retail Clinics Continue Gradual Expansion Through 2012: Deloitte Center for Health Solutions Report 4
... disposable pipette tips, TowerPacks are ... Each Sterilized TowerPack is individually ... to help protect tips from ... the red sticker, which indicates ...
... designed to optimize the accuracy and precision ... products is widely recognized by customers throughout ... extended over the years and now covers ... tips including filter tips, certified pure tips, ...
... Finntip Filters are ideal for ... or for any work where ... are designed for pipetting DNA/RNA ... and other. For applications requiring ...
... are ideal for PCR ... or for any work ... occur. They are designed ... infectious materials, labelled samples, ...
Medicine Products: