Navigation Links
BNCT, a new-generation radiation treatment, is effective in advanced head and neck cancer
Date:3/4/2011

Biologically targeted BNCT treatment is based on producing radiation inside a tumour using boron-10 and thermal neutrons. Boron-10 is introduced into cancer cells with the help of a special carrier substance (phenylalanine), after which the tumour is irradiated with lowenergy neutrons. The latter react with the boron to generate high-LET radiation, which may destroy the cancer cells. One to two BNCT treatment sessions may be sufficient to destroy a tumour, while keeping the impact of radiation on surrounding healthy tissue to a minimum.

A research reactor is currently used as the neutron source, but dedicated neutron accelerators being designed for BNCT.

Clinical trials to assess the efficacy and safety of BNCT in the treatment of locally recurrent head and neck cancer have been carried out at the Department of Oncology at Helsinki University Central Hospital (HUCH). Apart from palliative chemotherapy, conventional treatment was no longer considered possible for the patients treated in the BNCT trials.

A total of 30 patients referred to HUCH's Department of Oncology from hospitals around Finland took part in the trial. 76% of patients responded well to the treatment and 30% were still alive two years after treatment; although only one patient has survived 55 months. The results of the study, conducted by Professor Heikki Joensuu, have recently been published in the International Journal of Radiation Oncology, Biology, Physics.

BNCT treatment is provided by Boneca Corporation, which is based at the main campus of Helsinki University Central Hospital and is the world's only provider of radiation safetyaudited BNCT treatment. Owned by Clinical Research Institute HUCH Ltd, Sitra, Finnish Innovation Fund, and VTT Ventures Ltd., Boneca works closely with HUCH's Department of Oncology, and treatment-related decisions are taken jointly with the hospital's otolaryngology, radiation therapy and oncology specialists. Boneca is
'/>"/>

Contact: Dr. Seppo Pakkala
seppo.pakkala@hus.fi
358-505-596-549
University of Helsinki
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Many Dialysis Patients at Risk for High Radiation Exposure
2. ACR commission and committee chairs and former board chair to present at NIH Radiation Dose Summit
3. Protective strategy shields primate ovaries from radiation-therapy-induced damage
4. Smoking during radiation treatments reduces chance of overall survival
5. Breast cancer screening with MRI benefits women with radiation therapy history
6. New initiative provides materials to help lower radiation dose in pediatric fluoroscopic procedures
7. Risk of cancer increases with exposure to low-dose radiation
8. Princess Margaret Hospital researchers identify a key enzyme that affects radiation response
9. Practical Radiation Oncology publishes first issue
10. HIV-positive head and neck cancer patients benefit from radiation therapy
11. Breast Cancer Radiation Before 1984 Tied to Heart Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2015)... Injury lawyer Steven H. Heisler commented today on the ... legislature but which has not been signed to date by ... 449 with overwhelming bipartisan support on April 10, 2015, ... This bill ensures that fracking is prohibited in Maryland through ... of fracking to our water supplies and the air we ...
(Date:5/22/2015)... 22, 2015 The American College of ... in June. They will hold a webinar on the ... two-day class on Classical Chinese Medicine. , Webinar – ... Steve Given, the Dean of Clinical Education, will lead ... First Professional Doctorate program. ACTCM is currently developing this ...
(Date:5/22/2015)... May 22, 2015 Hundreds of ... behalf of individuals who allegedly experienced serious internal ... continue to move forward in the U.S. District ... Pretrial Order dated May 4, 2015, the Court ... and electronically stored information. Among other things, the ...
(Date:5/22/2015)... Combination therapy, or polytherapy, will likely ... pulmonary disorder (COPD) as the dominant companies like ... well as Germany’s Boehringer Ingelheim compete with each ... market payers, clinicians and patients be disposed to ... new ones? , In spite of recently approved ...
(Date:5/22/2015)... Family, friends, students, colleagues, mentors and fellow physicians ... D. Leffall, on Monday, May 18, with an 85th ... in the hospital’s Tower Auditorium. Leffall’s younger sister, 83-year-old ... to keep the secret. “I’d like to go in ... know something is up,” she said. , After more ...
Breaking Medicine News(10 mins):Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 2Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 3Health News:ACTCM Announces Upcoming June Events 2Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 2Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 3Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 4Health News:Chronic Obstructive Pulmonary Disorder Therapeutics Market Discussed in In-demand FirstWord Report Published at MarketPublishers.com 2Health News:Colleagues Surprise Dr. LaSalle Leffall with 85th Birthday Celebration 2
... Other Providers Would Likely Demand Similar,Treatment Next Year, ... released a new ad today warning policymakers,that other Medicare ... the "same prompt-pay deal" next year if Congress requires,pharmacists ... "Paying one group of Medicare providers twice as ...
... Older people are especially,at risk from heat-related health problems such ... currently experiencing, now is not,the time to do chores, run ... for all ages, but potentially life threatening,for older persons," according ... 10 tips for dealing with a heat wave:, 1. ...
... The 125,000-member American College of Physicians (ACP) today ... the Medicare Improvements for Patients and Providers Act of ... S. 3101 because it addresses and incorporates three of ... MD, FACP, wrote Senator Max Baucus (D-MT), chairman of ...
... June 9 Mylan Inc. (NYSE: MYL ),today ... from the U.S. Food and Drug Administration (FDA) for ... mg and 10,mg., Zaleplon Capsules are the generic ... of approximately $88 million for,the 12 months ending March ...
... donates $100,000 to American Red Cross, INDIANAPOLIS, June ... of Eli Lilly and Company (NYSE: LLY ), ... to aid,Indiana tornado and flood victims. More than 44 ... Mitch Daniels as a result of deadly,tornadoes and severe ...
... MADISON, N.J., June 9 Wyeth (NYSE: ... the Goldman Sachs Twenty-Ninth,Annual Global Healthcare Conference on ... for Wyeth will be Bernard Poussot, President and ... webcast live for investors at, http://www.wyeth.com and ...
Cached Medicine News:Health News:New PCMA Ad: Pharmacist 'Prompt Pay' Will Trigger 'Domino Effect' Among Other Medicare Providers 2Health News:How Seniors Can Beat the Heat 2Health News:ACP pledges support for Medicare improvements for Patients and Providers Act of 2008 2Health News:Lilly to Provide Aid to Indiana Tornado and Flood Victims 2
(Date:5/22/2015)... May 22, 2015 /CNW/ - More than fifty years ago, ... morning sickness in expectant mothers. Tragically, Thalidomide caused serious and ... Support has been provided to survivors over ... Canada in 1991 and settlements from ... a legal obligation to provide support, we have a clear ...
(Date:5/22/2015)... , May 22, 2015 Electrophysiologist ... Institute recently traveled to Boston, MA ... at the 2015 Heart Rhythm Society conference. These ... to focus on the ideas, people and technology ... Convergent is a hybrid, minimally invasive cardiac operation ...
(Date:5/22/2015)... NEW YORK , May 22, 2015 /PRNewswire/ ... approval of Zarxio (filgrastim-sndz) -- the first biosimilar ... -- points toward growth in the ... Information. The mainstream CMO industry is geared to ... infrastructure to produce major biopharmaceutical products. The healthcare ...
Breaking Medicine Technology:Statement from Minister Ambrose on Thalidomide 2Statement from Minister Ambrose on Thalidomide 3St. Joseph's Hospital Heart Institute Physician Presents at Heart Rhythm Society 2St. Joseph's Hospital Heart Institute Physician Presents at Heart Rhythm Society 3Kalorama: First FDA-Approved Biosimilar Brings Hope for CMO Growth 2Kalorama: First FDA-Approved Biosimilar Brings Hope for CMO Growth 3Kalorama: First FDA-Approved Biosimilar Brings Hope for CMO Growth 4
... 1, 2012  PDI, Inc. (Nasdaq: PDII ) ... and full year 2011 financial results on Wednesday, March ... conference call on Thursday, March 8, at 8:30 am ... March 8, 2012Time:8:30 am Eastern timeDial-in numbers:(866) 644-4654 (U.S. ...
... therapies for foot wounds are saving limbs, restoring mobility, ... who suffer from non-healing foot ulcers. "For ... wounds can be a tremendous problem, making these advanced ... clinical professor of surgery at Yale School of Medicine. ...
Cached Medicine Technology:Advanced Treatments Help Hard-to-Heal Diabetic Foot Ulcers—and Improve Lives 2Advanced Treatments Help Hard-to-Heal Diabetic Foot Ulcers—and Improve Lives 3
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: