Navigation Links
BIG research offers insight into aging -- 2 scientists awarded $200,000 prize
Date:8/13/2009

NEW YORK, August 12, 2009 -- Rochelle Buffenstein, PhD, professor, University of Texas Health Science Center at San Antonio and Luigi Fontana, MD, PhD, research associate professor, Washington University in St. Louis, were selected as recipients of the Breakthroughs in Gerontology (BIG) Award sponsored by the Glenn Foundation for Medical Research and the American Federation for Aging Research (AFAR). Established in 2005, the BIG Award provides $200,000 grants for high risk, original research that offers significant promise of yielding transforming discoveries in the fundamental biology of aging.

Dr. Buffenstein will investigate how regulation by the Nrf2 signaling pathwaya major detoxification pathwayprotects long-lived species such as the naked mole rat from cellular stress that contributes to age-related diseases. The naked mole rat is the longest-lived rodent known, living 8.6 times longer than similar-sized mice, and maintains cancer-free, good health for more than 85% of its 30-year lifespan. Its tissues show pronounced cellular resistance to most noxious agents. In contrast, most short-lived species, rather than fending off threats to their tissues, direct many of their resources into rapid growth and early reproduction and readily succumb to age-related diseases such as cancer. Understanding the mechanisms involved in this pathway may provide pivotal insights into aging.

Dr. Fontana seeks to better understand caloric restriction (CR), which has been shown to slow aging in certain laboratory animals. The precise molecular mechanisms responsible for this effect are not known, but likely involve the regulation of gene function. Recent findings in individuals on long-term CR with adequate nutrition observed protection against diabetes, hypertension, inflammation, clogged arteries and deterioration of heart function with aging. This is consistent with long-term effects of CR in monkeys and rodents. However, little is known about the
'/>"/>

Contact: Stacey Harris
Stacey@afar.org
212-703-9977
American Federation for Aging Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Sigma-Aldrich Offers Customizable Synthetic Extracellular Matrix for Stem Cell Research
2. Newly Published Research Indicates 97% of Apraxic Children Improving with Novel Nutritional Combination
3. Karmanos Chief Cancer Surveillance Researcher Discusses Study on Decreased Cancer Mortality Rates
4. Lifting weights reduces lymphedema symptoms following breast cancer surgery, Penn research shows
5. Researchers identify potential new avenue to attack cancer
6. Nicholas Vogelzang, MD, Joins US Oncology Research Network via Comprehensive Cancer Centers of Nevada
7. New Evidence-Based Research Shows that Universal Comprehensive Eye Exams Would Help More Children Succeed in School
8. Breakthrough in Alzheimers research
9. HerbalScience Research Identifies Specific Bioactives In Stabilized Rice Bran Extract that Impart Anti-Inflammatory Benefits
10. Stem Cell Advance May Further Disease Research
11. Researchers find alcoholics display abnormal brain activity when processing facial expressions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2015)... (PRWEB) April 18, 2015 More than ... sale now at TheCelebrityDresses.com, the #1 online store carrying ... ongoing many girls have got their perfect dresses for ... the celebrity fashion prom dresses at TheCelebrityDresses.com would be ... designed more than 2000 prom dresses inspired by the ...
(Date:4/18/2015)... ArcAngel ” was featured on NewsWatch as part of its ... coolest applications on the market for iOS, Android, ... expert, conducted the app review and shared with viewers how ... turbulent world, people may find themselves in dangerous situations where ... move, but some situations can be avoided if there was ...
(Date:4/17/2015)... Heritage Woods of McLeansboro, a Gardant ... Week Celebration on April 20 with a day full ... body and soul. , The community, which is located ... adults of all incomes, including those on Medicaid, who ... Living Week is observed every April and highlights the ...
(Date:4/17/2015)... 2015 ERGO-Pedic Products, LLC, which produces ... new products to help a broader range of people ... are the second most common visitors to doctors. , ... specifically to help relieve sitting pain. Then, only a ... of happy customers later, we began getting questions from ...
(Date:4/17/2015)... 2015 Florida Hospital Wesley Chapel, Florida ... Hospital Carrollwood were all selected as Top Workplaces in ... Pasco County, is ranked number one for large businesses ... was conducted in partnership with an independent research firm. ... hospital that opened in October of 2012 with a ...
Breaking Medicine News(10 mins):Health News:Prom Dresses 2015 on Sale at TheCelebrityDresses.com 2Health News:A Personal Safety Application was Featured on NewsWatch Television 2Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 2Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 3Health News:Seat Cushion Company Credits Customer Driven Design For Two New Products 2Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 2Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 3Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 4
... , WASHINGTON , Jan. 15 The National ... grants and free Mental Health First Aid training to support mental ... earthquake. , "Our thoughts are with the people of Haiti ... the efforts of many agencies and individuals that are providing disaster ...
... MAYWOOD, Ill. -- Most skin cancers are highly curable, but ... new study by Loyola University Health System researchers could lead ... drugs. The drugs would work by turning on a gene ... Mitchell Denning, Ph.D. The study was published Jan. 15, ...
... had better brain function in adulthood, researchers say , ... in children could prevent memory defects in adulthood, new ... condition can grow up to develop learning and memory ... which is given to help the kids grow taller ...
... , PALM DESERT, Calif. , ... Katy Perry has signed on to appear in ... fighting acne and finding Proactiv® Solution .  Katy will ... new 2010 campaign which will introduce new technology and services. ...
... treatment for chronic hepatitis C with pegylated-interferon (PEG-IFN) ... patients, so that a substantial proportion of patients ... therapeutic strategies for patients with chronic hepatitis C ... how the different drugs affect viral kinetics and ...
... is increasing worldwide and its prognosis is very ... for early detection and on surgical treatment for ... research team from China retrospectively evaluated 5311 liver ... and December 2003. Of these, 429 (8.1%) patients ...
Cached Medicine News:Health News:Emergency Grants and Mental Health First Aid Training Available to Meet Mental Health Needs After Haiti Earthquake 2Health News:Emergency Grants and Mental Health First Aid Training Available to Meet Mental Health Needs After Haiti Earthquake 3Health News:How sunlight causes skin cells to turn cancerous 2Health News:Singer-Songwriter Katy Perry Signs On to Tell Proactiv(R) Story 2Health News:Singer-Songwriter Katy Perry Signs On to Tell Proactiv(R) Story 3Health News:Singer-Songwriter Katy Perry Signs On to Tell Proactiv(R) Story 4
(Date:4/17/2015)... DUBLIN , Apr. 16, 2015 Research and ... addition of the "Corporate Reputation of Pharma in ... 2nd edition" report to their offering. ... perspectives from 130 patient groups with an interest in ... companies (and of the pharma industry as a whole) ...
(Date:4/17/2015)... , Apr. 16, 2015 Research and Markets ... of the "Corporate Reputation of Pharma in 2014 ... 1st Edition" report to their offering. ... compared opinions on the corporate reputation of the pharmaceutical ... mental health with the views of patient organisations representing ...
(Date:4/17/2015)... , April 17, 2015 TWi Pharmaceuticals, ... subsidiary, TWi Pharmaceuticals USA , has ... the United States.  It has been in close contact ... and expects to have its own label specialty generic ... in the U.S. pharma market. According to ...
Breaking Medicine Technology:Perspective of Diabetes Patient Groups on the Corporate Reputation of Pharma in 2014: 130 patient groups with an interest in diabetes from 34 countries 2Perspective of Diabetes Patient Groups on the Corporate Reputation of Pharma in 2014: 130 patient groups with an interest in diabetes from 34 countries 3Perspective of Diabetes Patient Groups on the Corporate Reputation of Pharma in 2014: 130 patient groups with an interest in diabetes from 34 countries 4Perspective of Diabetes Patient Groups on the Corporate Reputation of Pharma in 2014: 130 patient groups with an interest in diabetes from 34 countries 5Corporate Reputation of Pharma in 2014 - The Perspective of Mental Health Patient Groups - 1st Edition 2Corporate Reputation of Pharma in 2014 - The Perspective of Mental Health Patient Groups - 1st Edition 3
The vertical needle holder conveniently positions 20 needles vertically in numbered positions for easy loading....
... is a vacuum driven device designed to pull prostate ... Seeds are drawn into the clear tube tip by ... piece to create the vacuum. The prescribed sequence of ... tube tip before being placed into the needle. These ...
MT-BT-5011-25 Prostate seeding needle (set of 25 unloaded needles).,MT-BT-5011-P Prostate seeding needle, pre-plugged and pre-sterilized, unloaded or for use with MEDTECs ASAP™ pre-load seedin...
MT-BT-5001-25 prostate seeding needle (set of 25 unloaded needles).,MT-BT-5001-P prostate seeding needle, pre-plugged and pre-sterilized, unloaded or for use with MEDTECs ASAP™ pre-load seeding...
Medicine Products: