Navigation Links
BIDMC investigator to receive vascular biology award from the American Heart Association
Date:3/22/2011

BOSTON -- Alterations in blood vessel dilation lie at the heart of coronary artery health: When vessels dilate, blood and oxygen supplies successfully reach the heart. When vessels contract, blood and oxygen are diminished, leading to coronary artery disease.

The biology behind this course of events, known as vasodilation, occurs through nitric oxide, a gaseous molecule synthesized by an enzyme called eNOS, which relaxes the vascular smooth muscle cells lining the outer layer of coronary vessels. If, during this course of events, nitric oxide (NO) encounters another group of molecules known as reactive oxygen species (ROS), then NO is inactivated, and instead of dilating, blood vessels contract. In other words, ROS are harmful.

But a paper by Ruhul Abid, MD, PhD, of BIDMC's Center for Vascular Biology Research upends this long-held notion, demonstrating that ROS has another, beneficial role in the activation of eNOS and the nitric oxide production process and, in fact, is necessary to maintain coronary vasodilation.

This paradoxical discovery, published last spring in the American Heart Association journal Arteriosclerosis, Thrombosis, and Vascular Biology, was recently selected from more than 650 entries as the journal's most outstanding Vascular Biology paper of 2010. Abid will receive the AHA's 2011 Werner Risau New Investigator Award in Vascular Biology on April 29 in Chicago for this groundbreaking work.

"ROS are generally believed to play harmful roles in microvascular tone in hypertension, angiogenesis and vascular complications of arthritis and diabetes," explains Abid. "As a result, it's been widely assumed that by reducing ROS oxidants, you can improve cardiovascular function." In fact this is the premise underscoring the use of antioxidants, such as Vitamins E and C and beta carotene, to help prevent heart disease.

"But our findings now suggest that these high oxidant levels often found in the
'/>"/>

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. BIDMC researcher receives Young Investigator Award from Prostate Cancer Foundation
2. Scott & White Healthcare pathologist is co-investigator on breast cancer study
3. SEBM Young Investigator Awards for 2010
4. BUSM researcher receives prestigious young investigator award
5. Investigators examine colorectal cancer screening methods among diverse populations
6. University of Utah afib specialist, Marcos Daccarett, M.D., wins Young Investigator Award
7. UT Southwestern investigators perform head-to-head comparison of incontinence treatments
8. Damon Runyon Cancer Research Foundation awards $3.1M to 8 top young clinical investigators
9. Investigators identify gene associated with kidney disease in African-American population
10. SWOG names 5 cancer researchers outstanding Young Investigators
11. NCH investigators receive grant to distinguish bacterial infections from viral infections in infants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... hold great promise in helping people to reach ... devices help the wearers improve their wellness by ... information is organized into companion computer programs and ... quickly growing market for these devices, researchers at ... analyzed 13 of these activity monitors, such as ...
(Date:9/16/2014)... 16, 2014 (HealthDay News) -- Although magnesium sulfate is ... preterm delivery, new research suggests it won,t provide any ... effects of magnesium sulfate given to pregnant women, researchers ... behavioral, growth or functional outcomes among those children when ... old. The new findings don,t negate the fact ...
(Date:9/16/2014)... radiation therapy as part of breast conservation is ... hormone-receptor positive (HR+) invasive breast cancer. A new ... however, shows that combination may not be necessary ... , The results, which Fox Chase researchers presented ... Annual Meeting on Sunday, September 14, suggest that ...
(Date:9/16/2014)... September 16, 2014 Programs and policies ... hundreds of billions of dollars in savings for the ... the Commonwealth Fund. To help spur these types of ... to 10 collaborative groups from across the country to ... http://bit.ly/1wo4gsa ) - a handbook designed to assist groups ...
(Date:9/16/2014)... (PRWEB) September 16, 2014 Who:, The ... Anschutz Medical Campus and Children’s Hospital Colorado ... is the country’s leading pulmonary hypertension association that works to ... a disease of the lungs that affects the functioning of ... treatment, mean survivability is only 2.8 years. , What:, ...
Breaking Medicine News(10 mins):Health News:Do wearable lifestyle activity monitors really work? 2Health News:Do wearable lifestyle activity monitors really work? 3Health News:Researchers Don't See Long-Term Benefits From Drug for Preemies 2Health News:Benefit of endocrine therapy in elderly women with low risk hormone receptor positive breast cancer? 2Health News:Benefit of endocrine therapy in elderly women with low risk hormone receptor positive breast cancer? 3Health News:NQF Seeks Field Testing Groups for Population Health Guide 2Health News:NQF Seeks Field Testing Groups for Population Health Guide 3Health News:Help Fight Pulmonary Hypertension at the Colorado PH in the Park 2014 2
... June 30 Standard & Poor,s will make the,following changes ... the,close of trading on Wednesday, July 2:, -- S&P ... replace Getty Images Inc. (NYSE: GYI ) in the ... replace IDEXX Laboratories in the S&P,SmallCap 600. Getty Images is ...
... findings as fact , , MONDAY, June 30 (HealthDay News) -- ... HDL cholesterol and loss of memory. , The study, which has ... percent increased loss of memory on a word test for those ... with the highest levels. By age 60, the rate of memory ...
... than placebo, one expert says , , MONDAY, June 30 ... of placing intravenous (IV) lines in children, Canadian researchers ... by 34 percent in children getting IV lines when ... rate of inserting the lines, said lead researcher Dr. ...
... for two adults? Experts consider this question alongside new ... Liver Transplantation , a journal by John Wiley ... Wiley Interscience ( www.interscience.wiley.com ). , The shortage of ... increase opportunities for those in need of a transplant. ...
... researchers at the Ocean University of China has developed and ... can accurately measure wind speed and direction over large areas ... weather forecasting and sports. , As described in the ... published by the Optical Society, the mobile lidar station can ...
... June 30 Robbins & Myers, Inc.,(NYSE: RBN ... for the third quarter,results conference call scheduled today, June ... or 1-617-614-3525,with ID# 84552408. Replays of the call can ... # 63192398., Robbins & Myers, Inc. is a ...
Cached Medicine News:Health News:Standard & Poor's Announces Changes to U.S. Indices 2Health News:Standard & Poor's Announces Changes to U.S. Indices 3Health News:Research Links Low HDL Levels With Memory Loss 2Health News:Spray Cuts Kids' Pain When Getting IVs 2Health News:Experts examine challenges of split liver transplantation 2Health News:New technology may help Olympic sailing 2
(Date:9/16/2014)... Wash. , Sept. 16, 2014 /PRNewswire/ ... a late stage development company engaged primarily ... medical isotopes for diagnostic and therapeutic applications, ... for technology related to its brachytherapy products.  ... arise from its license from Battelle, under ...
(Date:9/16/2014)... -- Russia,s pharmaceutical ... Pharma 2020 Strategy provides incentives for local producers to ... foreign markets. These trends, however, were affected by recent ... political and economic sanctions imposed on Russia ... Russia responded to the US ...
(Date:9/16/2014)... Sept. 16, 2014 Surgeons at The Children,s ... a case report the first successful use of a ... year-old boy with failing Fontan circulation to bridge him ... 3 years old, the patient received a Fontan circulation ... single ventricle. "The Fontan operation is the final planned ...
Breaking Medicine Technology:Advanced Medical Isotope Corporation Licensed Brachytherapy Seed Patent Granted 2Advanced Medical Isotope Corporation Licensed Brachytherapy Seed Patent Granted 3Advanced Medical Isotope Corporation Licensed Brachytherapy Seed Patent Granted 4Global Medicines for Russia 213-Year-Old Boy with Failed Fontan Circulation Bridged to Transplant Using the SynCardia Total Artificial Heart, Published in Annals of Thoracic Surgery 213-Year-Old Boy with Failed Fontan Circulation Bridged to Transplant Using the SynCardia Total Artificial Heart, Published in Annals of Thoracic Surgery 3
... According to new data from,PAREXEL International Corporation (Nasdaq: ... the number of new,industry-sponsored clinical trial initiations, or ... in 2007. PAREXEL,s analysis shows that the,biopharmaceutical industry ... support of new clinical studies for drugs in,2007, ...
... June 20 GlaxoSmithKline,(NYSE: GSK ) today ... has extended the priority review period for PROMACTA(R),(eltrombopag) ... chronic idiopathic thrombocytopenic purpura, as they require more ... Fee action date has,been extended to September 19, ...
Cached Medicine Technology:PAREXEL Data Reveal A Record High Number of Clinical Trials Initiated 2PAREXEL Data Reveal A Record High Number of Clinical Trials Initiated 3PAREXEL Data Reveal A Record High Number of Clinical Trials Initiated 4PAREXEL Data Reveal A Record High Number of Clinical Trials Initiated 5GSK Update on FDA Review of Promacta(R) (Eltrombopag) 2
19 Gauge. Reusable. Block of 4 each....
18 gauge curved. Fine tip. Lightweight design offers precise hemostasis. Pencil design minimizes tissue trauma and induced astigmatism. Knurled handle provides a sure grip and better manipulation....
Set consist of two 23 gauge, stainless steel probes with blunt tips. Probes are 18 cm (7.0 inches) long with 30.5 cm (12 inches) of flexible tubing (O.D. - 0.60 mm, I.D. - 0.30 mm) attached onto the ...
Curved, soft flexible tip allows atraumatic entry through a retinal tear or hole for aspiration of subretinal fluids. 20 gauge x 25 mm cannula attached to 25 gauge x 6 mm tip with 13 mm flexible tubi...
Medicine Products: