Navigation Links
Azithromycin Doesn't Always Help Lungs in Cystic Fibrosis Patients
Date:5/4/2010

Antibiotic helped some with respiratory disease, but more study needed

TUESDAY, May 4 (HealthDay News) -- Treatment with the antibiotic azithromycin doesn't improve the lung function of children and teens with cystic fibrosis, U.S. researchers report.

"A vicious cycle of infection and inflammation causes progressive lung destruction and premature death in patients with cystic fibrosis [CF]. Treatment strategies have therefore included both antimicrobial and anti-inflammatory agents," Dr. Lisa Saiman, of Columbia University in New York City, said in a news release.

Over the past decade, studies have suggested that azithromycin, an antibiotic with both antimicrobial and anti-inflammatory activity, benefits CF patients.

Azithromycin is recommended as therapy for CF patients with chronic infection with the bacteria Pseudomonas aeruginosa, but there has not been enough evidence to support the benefit of azithromycin in other patients with CF, the researchers wrote.

This study, which investigated the possible benefits of expanding the antibiotic therapy to CF patients without the pathogen, included 260 children and teens with CF who were not infected with P. aeruginosa. They were randomly selected to receive either azithromycin or a placebo. After 24 weeks of treatment, there was no difference in lung function between the two groups.

However, researchers found that when compared with the placebo group, the azithromycin group had 50 percent fewer pulmonary exacerbations and 27 percent fewer patients who had to begin new oral antibiotics (other than azithromycin). On average, they also showed a 1.3-pound weight gain and a 0.34-unit increase in body-mass index (important because CF patients often need to gain weight). There were no differences in treatment groups in the use of intravenous or inhaled antibiotics or hospitalizations, Saiman and colleagues added.

They also found that
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. New studies on surgical options in inherited breast cancer show drastic treatment is not always best
2. SAN SnapShot Backup for VMWare - Does Your Backup Always Completes In Seconds, Is 1000x Faster and Costs 90% Less?
3. Rotary Clubs Always Pumped for World Water Day
4. Patient and doctor expectations from joint replacement surgeries not always aligned
5. Its Not Always Women and Children First
6. Liberal Thinking: It, and It Alone, Has Always Been the Force Behind Positive Social Changes in America
7. Methadone and Other Opioids Not Always Equivalent, Conversion Can Be Lethal
8. Top-rated hospitals dont always have superior outcomes
9. Research findings underscore needed action to safeguard lungs of young cancer survivors
10. New technique reduces tobacco smoke damage to lungs in mice
11. Discovery in Lungs May Lead to Treatment for Respiratory Virus
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)... Boston Celtics Legend and Basketball Hall of ... Board of Directors members, will be hosting their 34th ... 4-7. For the past 34 years, the Havlicek’s have ... for children by bringing together friends, families, and celebrities ... Havlicek Celebrity Fishing Tournament will be held from June ...
(Date:5/28/2015)... Senior Housing Assistance Group (SHAG) proudly announces a ... Seattle Mariners team that won a record tying 116 ... digital advertising for SHAG to help promote their affordable ... communities slated to open in the next 2 to ... and University Place. , Filming of new commercials starring ...
(Date:5/28/2015)... CA (PRWEB) May 28, 2015 ... clinic will now be offering Echocardiography Examinations to ... be performed by renowned Qualified Medical Examiner and ... The echocardiography test is a non-invasive and cost-effective ... who are critically ill or have undergone surgery. ...
(Date:5/28/2015)... CompanionDx , a Houston-based ... it will present their integrated solution of next-generation ... annual American Society of Clinical Oncology (ASCO) in ... DNA in a patient’s tumor via a small ... changes or somatic mutations. Pharmacogenomics testing establishes a ...
(Date:5/28/2015)... Newton, Mass. (PRWEB) May 28, 2015 ... a $17.5 million round of financing led by ... health solutions company dedicated to transforming health care by ... nation’s largest and most utilized network for exchanging medical ... its growing customer base, increase the breadth of its ...
Breaking Medicine News(10 mins):Health News:The Genesis Foundation Prepares for Their Final Annual John Havlicek Celebrity Fishing Tournament 2Health News:SHAG Announces New Spokesperson: Lou Piniella 2Health News:Healthpointe Is Now Offering Echocardiography Examinations at the Anaheim Clinic. 2Health News:CompanionDx® Launches Integrated Genomic Solution at ASCO Meeting 2Health News:Cambia Health Solutions Leads New Round of Investment in lifeIMAGE 2Health News:Cambia Health Solutions Leads New Round of Investment in lifeIMAGE 3Health News:Cambia Health Solutions Leads New Round of Investment in lifeIMAGE 4
... Rigel,Pharmaceuticals, Inc. (Nasdaq: RIGL ) today ... R788, a novel, oral Syk kinase inhibitor, in ... study showed that R788 (tamatinib fosdium) can improve,platelet ... body attacks and,destroys its own blood platelets. ...
... health assistance in disaster zones is to be presented ... Dr Johan von Schreeb shows that international assistance is ... assessment having been made of the affected population. ... in a number of disaster situations. He examined the ...
... disease, but most remain unaware of it, hampering efforts ... transplant, according to a study funded by the National ... Journal of the American Medical Association. , ... of the U.S. population now have chronic kidney ...
... Corporation,(Amex: CVM ) announced today that its Board ... ensure that all of its stockholders,receive fair and equal ... of CEL-SCI. Geert Kersten, Chief Executive Officer, said ... stage for a cancer indication that has a,multi- billion ...
... the progression of chronic hepatitis C and advanced liver ... to eradicate the disease, a national study in which ... found. , Patients in the trial who were treated ... levels and liver inflammation, but the trial unequivocally demonstrated ...
... children , FRIDAY, Nov. 9 (HealthDay News) -- Certain ... according to studies presented this week at the American ... study found that abatacept, used to treat adults with ... treatment for children and adolescents with severe, treatment-resistant juvenile ...
Cached Medicine News:Health News:Rigel R788 Raises Platelet Counts in Immune Thrombocytopenic Purpura (ITP) Patients in Phase 2 Study 2Health News:Rigel R788 Raises Platelet Counts in Immune Thrombocytopenic Purpura (ITP) Patients in Phase 2 Study 3Health News:Rigel R788 Raises Platelet Counts in Immune Thrombocytopenic Purpura (ITP) Patients in Phase 2 Study 4Health News:Humanitarian assistance often lacks needs assessment 2Health News:Chronic kidney disease rises while most people with the condition remain unaware 2Health News:CEL-SCI Corporation Announces Adoption of Shareholder Rights Plan 2Health News:CEL-SCI Corporation Announces Adoption of Shareholder Rights Plan 3Health News:Interferon does not slow or stop hepatitis C from worsening, study finds 2Health News:Drugs Can Ease Juvenile Rheumatoid Arthritis 2
(Date:5/28/2015)... YORK , May 27, 2015 The ... $416 billion in 2014 and with growth of 8% ... three categories out of pocket: directly on expenditures, co-pays ... drug purchases, and on premiums.  The publisher made its ... Expenditures in the United States ...
(Date:5/28/2015)... , May 28, 2015 A ... - Size, Industry Analysis, Trends, Opportunities, Growth and Forecast, ... $3.6 billion by 2020. The secondary syphilis testing would ... Latin America , Middle ... (LAMEA) market accounted for about 43% revenue share of ...
(Date:5/28/2015)... May 28, 2015  Service Strategies Corp., a ... that Fresenius Kabi, a global healthcare company that ... transfusion and clinical nutrition, has achieved certification under ... Standards for the seventh consecutive year. ... based upon a stringent set of performance criteria ...
Breaking Medicine Technology:Report: U.S. Out-of-Pocket Healthcare Spending Reaches $416 Billion 2Report: U.S. Out-of-Pocket Healthcare Spending Reaches $416 Billion 3Global Syphilis Testing Market is Expected to Reach $3.6 Billion, by 2020 - Allied Market Research 2Global Syphilis Testing Market is Expected to Reach $3.6 Billion, by 2020 - Allied Market Research 3Fresenius Kabi Recognized by Service Strategies Corp. for Technical Service Excellence 2Fresenius Kabi Recognized by Service Strategies Corp. for Technical Service Excellence 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: