Navigation Links
Avoiding or controlling diabetes may reduce cancer risk and mortality
Date:4/3/2011

ORLANDO, Fla. Results of the NIH-AARP Diet and Health Study revealed that diabetes is associated with lower risk of prostate cancer in men but with higher risk of other cancers in both men and women. The data, to be presented at the AACR 102nd Annual Meeting 2011, held here April 2-6, also showed an association between diabetes and higher cancer mortality rates.

Previous epidemiologic studies have shown an association between diabetes and an increased risk for cancers including colorectal, liver and pancreas, according to Gabriel Lai, Ph.D., a cancer prevention fellow at the National Cancer Institute.

"Our results provide further evidence that abnormal insulin and glucose signaling may contribute to cancer initiation and development," he said. "There are myriad benefits from avoiding diabetes through exercise, diet and maintaining a healthy body weight. Our study confirms additional benefits in the form of reduced morbidity and mortality from certain cancers."

Lai and colleagues conducted a prospective study using data from more than 500,000 predominantly white, non-Hispanic men and women aged 50 to 71 years. From 1995 to 1996, the participants completed questionnaires about diet, lifestyle and whether or not they had diabetes. Researchers followed the patients for 11 years.

Results showed that diabetes was associated with an 8 percent increased risk for cancer among women and a 4 percent decreased risk for men. In previous research, a decreased risk for prostate cancer was associated with diabetes, which researchers believe might be due to the lower testosterone levels associated with diabetes. After excluding prostate cancer from their evaluation, Lai and colleagues found that diabetes was associated with a 9 percent increased risk for cancer in men.

As for mortality, diabetes was associated with an 11 percent increased risk in women and a 17 percent increased risk in men.

"These risks appeared independent from other cancer risk factors, such as obesity and cigarette smoking," Lai said.

After evaluating by cancer site, the researchers found diabetes was associated with a significant increase in risk for colon, rectal and liver cancers among men and women. In men, diabetes was associated with an increased risk for pancreatic and bladder cancers; in women, it was associated with an increased risk for stomach, anal and endometrial cancers. No association was found between diabetes and lung, skin or other cancers.

"Follow-up studies to identify the biologic mechanisms involved should be performed to build upon confirmed findings," Lai said.


'/>"/>

Contact: Jeremy Moore
Jeremy.Moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Related medicine news :

1. Gift-Giving, for Many Men, Means Avoiding Rejection
2. Some Tips for Avoiding Injury on Super Bowl Sunday
3. iCycleBeads: New iPhone application for planning and avoiding pregnancy
4. Avoiding Child Obesity: Children Eat Vegetables with Author of New Picture Book, A Hungry Lion in My Tummy
5. Avoiding Dairy Due to Lactose Intolerance is Unnecessary in Most Cases and May Pose Diet and Health Risks, Concludes National Institutes of Health Consensus Development Conference Panel
6. UC Davis pain research may pave the way to understanding and controlling chronic pain
7. New clue to controlling skin regeneration -- as well as skin cancer
8. Controlling the rising costs of cardiovascular care
9. Controlling symptoms can lead to improved quality of life for end-of-life patients
10. Health Secretary Encourages Pennsylvanians to Learn the ABCs of Controlling Diabetes
11. Bariatric surgery reduces long-term cardiovascular risk in diabetes patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... ... 23, 2017 , ... PM360, the premier information resource for ... winners of its 3rd Annual ELITE Awards. The ELITE (Exceptional • Leaders • ... industry today. , Out of more than 500 submissions, 100 winners were selected ...
(Date:5/23/2017)... ... May 23, 2017 , ... New England Journal Of Medicine Confirms ... a Policy Response”, -The Rory Staunton Foundation Calls on Health & Human Services, Tom ... of Sepsis ( http://www.rorystauntonfoundation.org ) today reported on a new study released on May ...
(Date:5/23/2017)... (PRWEB) , ... May 23, 2017 , ... ... certification body for exercise professionals, is pleased to announce the organization’s Certified Strength ... , The NCSF Certified Strength Coach (CSC) program validates the competency of qualified ...
(Date:5/23/2017)... Newport Beach, CA (PRWEB) , ... May 23, ... ... Board Certified Facial Plastic and Reconstructive Surgeon Dr. Kevin Sadati, is pleased to ... patients interested in building collagen and elastin in their face, neck, and body ...
(Date:5/23/2017)... ... May 23, 2017 , ... ... educating patients on peri-implantitis in Las Vegas, NV, and the importance ... custom gum disease consultation and leading care for peri-implantitis, with or without a ...
Breaking Medicine News(10 mins):
(Date:5/9/2017)... -- Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH), ... has earned a spot on Forbes, "America,s ... ranked among 500 U.S. employers as well as in ... Services. The annual Forbes rankings ... of over 30,000 employees across 25 industries. The survey ...
(Date:5/8/2017)... , May 8, 2017 MACRA ... transition from fee for service reimbursement. Black Book Research ... 1.       The Market for MIPS Compliance ... 77% of physician practices with 3 or more clinicians ... Solutions by Q4. "Given the magnitude of the changes, ...
(Date:5/6/2017)... , May 5, 2017  Hill-Rom Holdings, Inc. ... add approximately 100,000 square feet to its Welch Allyn ... 2016 its commitment to bring more than 100 new ... where Welch Allyn has maintained a significant presence for ... accommodate these new positions, a large portion of which ...
Breaking Medicine Technology: