Navigation Links
Avoiding or controlling diabetes may reduce cancer risk and mortality
Date:4/3/2011

ORLANDO, Fla. Results of the NIH-AARP Diet and Health Study revealed that diabetes is associated with lower risk of prostate cancer in men but with higher risk of other cancers in both men and women. The data, to be presented at the AACR 102nd Annual Meeting 2011, held here April 2-6, also showed an association between diabetes and higher cancer mortality rates.

Previous epidemiologic studies have shown an association between diabetes and an increased risk for cancers including colorectal, liver and pancreas, according to Gabriel Lai, Ph.D., a cancer prevention fellow at the National Cancer Institute.

"Our results provide further evidence that abnormal insulin and glucose signaling may contribute to cancer initiation and development," he said. "There are myriad benefits from avoiding diabetes through exercise, diet and maintaining a healthy body weight. Our study confirms additional benefits in the form of reduced morbidity and mortality from certain cancers."

Lai and colleagues conducted a prospective study using data from more than 500,000 predominantly white, non-Hispanic men and women aged 50 to 71 years. From 1995 to 1996, the participants completed questionnaires about diet, lifestyle and whether or not they had diabetes. Researchers followed the patients for 11 years.

Results showed that diabetes was associated with an 8 percent increased risk for cancer among women and a 4 percent decreased risk for men. In previous research, a decreased risk for prostate cancer was associated with diabetes, which researchers believe might be due to the lower testosterone levels associated with diabetes. After excluding prostate cancer from their evaluation, Lai and colleagues found that diabetes was associated with a 9 percent increased risk for cancer in men.

As for mortality, diabetes was associated with an 11 percent increased risk in women and a 17 percent increased risk in men.

"These risks appeared independent from other cancer risk factors, such as obesity and cigarette smoking," Lai said.

After evaluating by cancer site, the researchers found diabetes was associated with a significant increase in risk for colon, rectal and liver cancers among men and women. In men, diabetes was associated with an increased risk for pancreatic and bladder cancers; in women, it was associated with an increased risk for stomach, anal and endometrial cancers. No association was found between diabetes and lung, skin or other cancers.

"Follow-up studies to identify the biologic mechanisms involved should be performed to build upon confirmed findings," Lai said.


'/>"/>

Contact: Jeremy Moore
Jeremy.Moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Related medicine news :

1. Gift-Giving, for Many Men, Means Avoiding Rejection
2. Some Tips for Avoiding Injury on Super Bowl Sunday
3. iCycleBeads: New iPhone application for planning and avoiding pregnancy
4. Avoiding Child Obesity: Children Eat Vegetables with Author of New Picture Book, A Hungry Lion in My Tummy
5. Avoiding Dairy Due to Lactose Intolerance is Unnecessary in Most Cases and May Pose Diet and Health Risks, Concludes National Institutes of Health Consensus Development Conference Panel
6. UC Davis pain research may pave the way to understanding and controlling chronic pain
7. New clue to controlling skin regeneration -- as well as skin cancer
8. Controlling the rising costs of cardiovascular care
9. Controlling symptoms can lead to improved quality of life for end-of-life patients
10. Health Secretary Encourages Pennsylvanians to Learn the ABCs of Controlling Diabetes
11. Bariatric surgery reduces long-term cardiovascular risk in diabetes patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... ... August 18, 2017 , ... The Golseth Agency, a Texas ... Worth area, is spearheading a regional charity campaign organized to provide support to Christina ... June of this year, Christina and her children returned from out of town to ...
(Date:8/18/2017)... , ... August 18, 2017 , ... Inc. magazine has ... the most prestigious ranking of the nation's fastest-growing private companies. This marks the eighth ... Inc. 5000 ranking . This year’s ranking reflects ASH’s 76 percent overall revenue ...
(Date:8/18/2017)... ... ... “Beyond Our Imaginations: The Infinite God”: shows the importance of God in living a ... published author, Mark Lawrence, born in Michigan, the author has lived in various communities ... man of God is that I have to be more mindful of feminine qualities ...
(Date:8/18/2017)... ... 2017 , ... “Steve the Snake”: an entertaining and moral-based short story about ... published author, Harold Flash Haskins Jr., a husband, father and grandfather who served as ... “I write moral-based short stories for children and teens. My goal is to teach ...
(Date:8/17/2017)... Wilmington, Delaware (PRWEB) , ... August 17, 2017 , ... ... bedside, well actually, stretcher side nurse, she took with her a dream to make ... science of healthcare. Specifically, ensuring communication skills were integrated into healthcare provider education. ...
Breaking Medicine News(10 mins):
(Date:8/14/2017)... and PETACH TIKVAH, Israel , ... BCLI), a leading developer of adult stem cell technologies ... quarter ending June 30, 2017. ... preparing for our pivotal Phase 3 trial to investigate ... , President and Chief Executive Officer of BrainStorm. "We ...
(Date:8/8/2017)... 8, 2017  BioLineRx Ltd. (NASDAQ/TASE: BLRX), a clinical-stage ... its financial results for the second quarter ended June ... second quarter 2017 and to date: ... programs for the Company,s lead project, BL-8040: ... with BL-8040 as novel stem cell mobilization treatment for ...
(Date:8/7/2017)... Ind. , Aug. 7, 2017 Zimmer Biomet ... musculoskeletal healthcare, today announced that its Board of Directors has ... for the third quarter of 2017. ... be paid on or about October 27, 2017 to stockholders ... 22, 2017.  Future declarations of dividends are subject to approval ...
Breaking Medicine Technology: