Navigation Links
Avocados may help prevent oral cancer, OSU study shows
Date:9/4/2007

Columbus, Ohio -- Nutrients taken from avocados are able to thwart oral cancer cells, killing some and preventing pre-cancerous cells from developing into actual cancers, according to researchers at Ohio State University.

Researchers found that extracts from Hass avocados kill or stop the growth of pre-cancerous cells that lead to oral cancer. Hass avocados are year-round fruits known for their distinctive bumpy skin that turns from green to purplish-black as they ripen.

While there are more than 500 varieties of avocados grown worldwide, Hass avocados are the most readily available at supermarkets nationwide. Similar research has not been conducted on other varieties of avocados.

The findings are published online in the journal Seminars in Cancer Biology.

Lead author Steven M. D'Ambrosio, a member of the molecular carcinogenesis and chemoprevention program at Ohio State's Comprehensive Cancer Center, also wrote an accompanying editorial for the journal, discussing the cancer-fighting potential of fruits and vegetables. D'Ambrosio collaborated with Haiming Ding in Ohio State's College of Medicine.

Studies have long associated the consumption of fruits and vegetables with a reduced risk for various types of human cancer. The protective effect is attributed to the high levels of phytonutrients or phytochemicals plant compounds thought to have health-protecting qualities that are often found in dark colored fruits and vegetables.

"As far as we know, this is the first study of avocados and oral cancer," says D'Ambrosio. "We think these phytochemicals either stop the growth of precancerous cells in the body or they kill the precancerous cells without affecting normal cells. Our study focuses on oral cancer, but the findings might have implications for other types of cancer. These are preliminary findings, and more research is needed."

D'Ambrosio, who collaborated with researchers in Ohio State's College of Pharmacy, found that phytochemicals extracted from avocados target multiple signaling pathways and increase the amount of reactive oxygen within the cells, leading to cell death in pre-cancerous cell lines. But the phytochemicals did not harm normal cells.

"These studies suggest that individual and a combination of phytochemicals from the avocado fruit may offer an advantageous dietary strategy in cancer prevention," says Ding, who is a member of the division of radiobiology, department of radiology.

Avocados are chock-full of beneficial antioxidants and phytonutrients, including vitamin C, folate, vitamin E, fiber and unsaturated fats. They are naturally sodium-free, contain no trans fats and are low in saturated fat, making them a healthy addition to any diet, D'Ambrosio says.

"The future is ripe for identifying fruits and vegetables and individual phytonutrients with cancer preventing activity," writes D'Ambrosio in the journal's editorial. "As we identify the molecular mechanisms and targets by which individual phytonutrients prevent cancer, we may be able to improve upon nature by formulating phytonutrient cocktails for specific cancers and individual susceptibility and risk."


'/>"/>

Contact: Eileen Scahill
Eileen.Scahill@osumc.edu
614-293-3737
Ohio State University
Source:Eurekalert

Related medicine news :

1. Asthma may actually be prevented by Dust and Dirt
2. Nearly all asthma deaths preventable
3. Breast Feeding prevents obesity later on in life
4. Lose stomach for Life....Preventive removal of stomach saves the risk of cancer
5. Regular exercise prevents hip fractures
6. Prevention is better than cure
7. Prevention of cataracts
8. Gel prevents pregnancy
9. Medications to Prevent Relapse to Cocaine Use
10. Estrogen Does Not Prevent Recurrent Strokes
11. Over-The-Counter Drugs May Prevent Alzheimers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... 13, 2017 , ... Lori R. Somekh, founder of the Law Office ... of elder law and special needs planning attorneys. “Membership in ElderCounsel helps our office ... forum to network with elder law attorneys nationwide,” said Somekh. , ElderCounsel ...
(Date:10/13/2017)... ... , ... Ellevate Network, the leading network for professional women, brought together some ... at their inaugural Summit in New York City in June. The event was livestreamed ... over 3 million. To watch the Mobilize Women video, click here . ...
(Date:10/13/2017)... , ... October 13, 2017 , ... ... and Agile Software Development, has been awarded a contract by the Center for ... Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in a ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... sleep apnea using cutting-edge Oventus O2Vent technology. As many as 18 ... characterized by frequent cessation in breathing. Oral appliances can offer significant relief to ...
(Date:10/12/2017)... ... ... The American College of Medical Informatics (ACMI) will present the 2017 Morris F. ... AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is taking place ... the field of medical informatics, this prestigious award is presented to an individual whose ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... West Pharmaceutical Services, Inc. (NYSE: ... drug administration, today announced that it will release third-quarter ... October 26, 2017, and will follow with a conference ... 9:00 a.m. Eastern Time. To participate on the call, ... ID is 94093362. ...
(Date:10/11/2017)... 2017  Caris Life Sciences ® , a leading ... of precision medicine, today announced that St. Jude Medical ... Alliance™ (POA) as its 17 th member. Through ... Crosson Cancer Institute will help develop standards of care ... profiling, making cancer treatment more precise and effective. ...
(Date:10/11/2017)... Holdings, Inc. ("Hill-Rom") (NYSE: HRC), today provided an update ... Puerto Rico , where the company manufactures ... Following a comprehensive onsite assessment, the ... temporary loss of power and minimal water damage due ... have resumed, and the company expects to return to ...
Breaking Medicine Technology: