Navigation Links
Averting postsurgical infections in kids: Give antibiotics within hour before first incision
Date:7/18/2008

Giving children preventive antibiotics within one hour before they undergo spinal surgery greatly reduces the risk for serious infections after the surgery, suggests a Johns Hopkins study to be published in the August issue of Pediatric Infectious Disease Journal (also available online ahead of print). Children who received antibiotics outside of the golden one-hour window were three and half times more likely to develop serious infections at the surgery site, researchers report, pointing out that something as simple as ensuring that a child gets timely prophylaxis can prevent serious complications and reduce the length of hospital stay.

"When it comes to preventing infections, when a child gets antibiotics appears to be one of the most critical yet most easily modifiable risk factors, and may matter just as much as the type and dosage of the medication ,"says lead researcher Aaron Milstone, M.D., infectious disease specialist at the Johns Hopkins Children's Center. "The moral of this is that an ounce of timely prevention is indeed worth a pound of treatment."

Nearly 780,000 postsurgical infections occur in the United States each year, according to estimates from the Institute for Healthcare Improvement. An infection after surgery nearly doubles a patient's risk of death, doubles a patient's hospital stay and adds up to $50,000 to treatment costs per patient, researchers say.

While preoperative antibiotic prophylaxis is standard in adults, there are no standard guidelines on how to administer antibiotics in children undergoing surgery.

Reviewing nearly 1,000 spinal fusion surgeries performed in children over a six-year period at Hopkins, investigators found 36 deep surgical site infections. More serious than superficial skin infections, these can cause serious complications and require aggressive treatment including additional surgeries and long-term antibiotics. Of the 36 cases, 28 percent received medication outside the one-hour window, either more than an hour before incision or after the surgery began. Other factors affecting infection risk included underlying medical conditions and previous spinal surgeries, researchers found.

Even though spinal fusion surgeries are complex procedures and thus carry higher risk for deep-site infections, the findings are likely relevant to many types of surgical procedures, the researchers say, because timing is always critical when administering antibiotics, either as treatment or prevention.


'/>"/>

Contact: Katerina Pesheva
epeshev1@jhmi.edu
410-516-4996
Johns Hopkins Medical Institutions
Source:Eurekalert

Related medicine news :

1. IOM report on averting crisis in care of older Americans releases April 14
2. Lung Infections Cost Hospitals More Than $10B in 2006
3. New Ear Tube Device Helps Treat Infections Faster
4. MRSA Infections Can Bug Fitness Buffs
5. The Wound Institute(R) Launches Educational Course on Chronic Wound Infections
6. National Press Club to Host NEWSMAKER Media Briefing on Global Health and the Infections of Poverty - Neglected Tropical Diseases
7. More severe bone infections, health complications in children linked to MRSA, researchers find
8. Doubling of sexually transmitted infections among over-45s in under a decade
9. Neglected infections of poverty in US disable hundreds of thousands of Americans annually
10. Overcrowding and understaffing in hospitals increases levels of MRSA infections
11. American Academy of Dermatology Research Shows Athletes Susceptible to Antibiotic-Resistant Staph Infections
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... ... issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the ... several important health care topics including advance care planning, healthcare costs and patient ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set of ... or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, Serenity ... event. , Trauma sufferers tend to feel a range of emotions, from depression, guilt, ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with ... Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty Network, ... M. Weintraub as a prominent plastic surgeon and the network’s newest partner. ... the most handsome men, look naturally attractive. Plastic surgery should be invisible.” He ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
(Date:6/23/2016)... -- Any dentist who has made an implant supported denture ... of them do not even offer this as a viable ... costs involved. And those who ARE able to offer that ... cost that the majority of today,s patients would not be ... , founder of Dental Evolutions Inc. and inventor of Implanova ...
(Date:6/23/2016)... June 23, 2016  In a startling report released today, ... residents by lacking a comprehensive, proven plan to eliminate prescription opioid ... ranking of how states are tackling the worst drug crisis in ... states – Kentucky , New Mexico ... . Of the 28 failing states, three – ...
Breaking Medicine Technology: