Navigation Links
Avandia's Heart Risk Higher Than Others in Its Class
Date:11/24/2008

A similar diabetes drug, Actos, doesn't seem to carry same dangers, study finds

MONDAY, Nov. 24 (HealthDay News) -- The widely used diabetes drug Avandia -- already controversial because of cardiovascular side effects -- may be riskier than Actos, another drug in the same class, researchers reported Monday.

The risk of heart failure and death for older diabetics appears greater with Avandia (rosiglitazone) than with Actos (pioglitazone), both of which are part of a class of drugs called thiazolidinediones, Harvard University researchers said.

Avandia and Actos are used to lower blood sugar in patients with type 2 diabetes. Recent studies suggested that the risk for heart failure, death and heart attack were increased with Avandia, touching off a controversy that resulted in new FDA-mandated label warnings about the drug.

"By contrast, Actos did not appear to increase the risk of cardiac events," said lead researcher Dr. Wolfgang C. Winkelmayer, an assistant professor of medicine at Harvard Medical School. "One could get the impression that Actos led to the reduction of heart attacks."

Indirectly, people inferred that it might be better to use Actos, because Avandia has cardiovascular risks associated with it, Winkelmayer said.

"We did find that patients using rosiglitazone actually had an increased risk of mortality from any cause. We did not find a difference in heart attacks and strokes," Winkelmayer said. But, he added, more patients taking Avandia were hospitalized for heart failure.

Winkelmayer noted differences in drugs in the same class are not unusual. For example, cholesterol-lowering statins (which include Crestor, Lipitor and Zocor) have different side effects, he said.

The new research, published in the Nov. 24 issue of the Archives of Internal Medicine, received funding from the American Heart Association, as well drug makers Amgen and GlaxoSmithKline, w
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3 4

Related medicine news :

1. Drug for cluster headaches may cause heart problems
2. Use of certain lipid measures not more effective in predicting coronary heart disease
3. Restricting Blood Flow May Help Heart Bypass Patients
4. Urban Smog Tough on Young Adults Hearts
5. Stanford study highlights cost-effective method of lowering heart disease risks
6. Vitamin Es lack of heart benefit linked to dosage
7. Drug That Lowers Resting Heart Rate Being Tested
8. Heart Attack Boosts Diabetes Risk
9. Embryonic Stem Cells Repair Human Heart
10. U of M study: Early treatment can reverse heart damage
11. Embryonic Human Stem Cells May Help Repair Heart Muscle, Lab Study Shows
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Avandia's Heart Risk Higher Than Others in Its Class
(Date:7/11/2014)... Volunteers from Scientology Churches and Missions ... drug education lectures, forums and conferences, information stands, sports ... the world. , Drug abuse is an international epidemic. ... abuse of alcohol and illicit drugs costs more than ... productivity and healthcare. , In the face of ...
(Date:7/11/2014)... (PRWEB) July 11, 2014 Datalogic brings ... in improving sanitation hospital wide. With their new ... spread of disease, like the devastating MRSA, which claimed ... Gryphon GD4400-HC 2D and the Gryphon GM4400-HC ... barcodes and can even read barcodes off of troublesome ...
(Date:7/11/2014)... U.S. health officials have concluded that it,s highly unlikely ... a safety mishap last month. But, the U.S. ... a moratorium on the transfer of any dangerous germs ... report issued Friday, the CDC outlined several measures the ... doesn,t occur again. Last month, as many as 75 ...
(Date:7/11/2014)... Global enterprises today are shifting towards ... management activities. Managed services offer these global enterprises a ... slowdown resulted into rising operational costs to companies. The ... to be the global market driver for expanding the ... managed services market is estimated to grow from $142.75 ...
(Date:7/11/2014)... (July 10, 2014) Obese and overweight firefighters ... health care providers, according to new research from ... Houston (UTHealth). , National guidelines state that health ... importance of maintaining a healthy weight. Firefighters have ... the leading cause of line-of-duty deaths in firefighters. ...
Breaking Medicine News(10 mins):Health News:Scientologists Taking Action against Drug Abuse 2Health News:Scientologists Taking Action against Drug Abuse 3Health News:Stop Spreading Disease with the New Disinfectant-Ready Bar Code Scanner 2Health News:Stop Spreading Disease with the New Disinfectant-Ready Bar Code Scanner 3Health News:CDC Issues Tough Report on Anthrax Scare 2Health News:North America Managed Services Market Worth $68.65 Billion by 2018 - New Report by MicroMarket Monitor 2Health News:North America Managed Services Market Worth $68.65 Billion by 2018 - New Report by MicroMarket Monitor 3Health News:North America Managed Services Market Worth $68.65 Billion by 2018 - New Report by MicroMarket Monitor 4
... and hyperactivity disorder (ADHD) are more than three times ... dementia than those without, according to research in the ... . Researchers from Argentina confirmed the link during ... 149 healthy controls, matched by age, sex and education. ...
... HealthDay Reporter , MONDAY, Jan. 17 (HealthDay News) -- ... actually measure up, according to new research. Dermatologists ... protection from the sun,s ultraviolet rays and found only ... which can penetrate glass. "The vast majority of ...
... and people in the southern United States who were newly ... years experienced greater HIV/AIDS-related morbidity compared to men and people ... The findings, published in the February 15 issue of ... to improve the health of these populations in order to ...
... HealthDay Reporter , MONDAY, Jan. 17 (HealthDay ... You tend to befriend others with similar or complementary ... University of California, San Diego found that gene clusters ... predisposition to befriend others in the same geographic area. ...
... other illnesses and patient embarrassment may prevent dermatologists, ... examinations, according to a report in the January ... of the JAMA/Archives journals. However, dermatologists are significantly ... conduct such screenings. Skin cancer is the ...
... HealthDay Reporter , MONDAY, Jan. 17 (HealthDay News) ... to the development of psychological disorders such as depression, researchers ... are more likely to become addicted to video games (which ... a lot of hours playing these games, have trouble fitting ...
Cached Medicine News:Health News:Adult ADHD significantly increases risk of common form of dementia 2Health News:Adult ADHD significantly increases risk of common form of dementia 3Health News:Despite Claims, Many Daily Moisturizers Don't Shield Against Sun: Study 2Health News:Despite Claims, Many Daily Moisturizers Don't Shield Against Sun: Study 3Health News:Sex, race, and geography influence health outcomes following primary HIV infection 2Health News:Your Genes Help You Choose Your Friends, Study Says 2Health News:Your Genes Help You Choose Your Friends, Study Says 3Health News:Clinicians cite time, patient embarrassment as barriers to performing skin cancer exams 2Health News:Video Game 'Addiction' Tied to Depression, Anxiety in Kids 2Health News:Video Game 'Addiction' Tied to Depression, Anxiety in Kids 3
(Date:7/10/2014)... July 10, 2014 Integrated Silicon Solution, Inc. ... memory and analog IC solutions, today announced that it ... 24, 2014, at 7:00 a.m. Pacific Time (10:00 a.m. ... the fiscal 2014 third quarter ended June 30, 2014. ... dial 1-888-556-4997 before 6:50 a.m. Pacific time on July ...
(Date:7/10/2014)... 10, 2014  Valeant Pharmaceuticals International, Inc. (NYSE: ... has completed the sale to Galderma of all rights ... held by Valeant for $1.4 billion in cash, pursuant ... recently completed its acquisition of Galderma. ... products to a company that is firmly committed to ...
(Date:7/10/2014)... -- CVS Caremark Corporation (NYSE: CVS ) today ... dividend of $0.275 (27.5 cents) per share on the corporation,s ... to holders of record on July 21, 2014. ... to helping people on their path to better health as ... States . Through the company,s more than 7,600 CVS/pharmacy ...
Breaking Medicine Technology:
Zebras H 2824-Z Healthcare Starter Kit includes everything you need to start printing wristbands today: the H 2824-Z direct thermal printer, a pre-installed Media Adapter Guide, and a roll of adult-s...
... Hugs® system software presents only ... a familiar Windows-based PC environment. Up ... connected at other locations throughout the ... network (LAN). Nurses, security personnel and ...
... is designed to protect a wandering resident ... lost or injured. Such residents typically have ... have suffered a head injury., At-risk residents ... wrist or ankle, and points of exit ...
... be programmed to send hospital-defined ... device needs servicing, preventive maintenance ... patient or staff member needs ... ID-tag includes the current location ...
Medicine Products: