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Autopsy-based study examines prevalence of atherosclerosis among US service members
Date:12/25/2012

Among deployed U.S. service members who died of combat or unintentional injuries between 2001-2011 and underwent autopsies, the prevalence of coronary atherosclerosis was 8.5 percent, with factors associated with a higher prevalence of the disease including older age, lower educational level and prior diagnoses of dyslipidemia, hypertension, and obesity, according to a study in the December 26 issue of JAMA.

"An early breakthrough in the understanding of the natural history of atherosclerotic heart disease was achieved in 1953, when Enos and colleagues at the Armed Forces Institute of Pathology reported a 77 percent prevalence of coronary atherosclerosis among U.S. soldiers killed in the Korean War. By demonstrating anatomically that atherosclerosis affected a large proportion of young individuals without clinical evidence of heart disease, their study revolutionized the understanding of the onset and progression of cardiovascular disease. A follow-up report in the Vietnam War era, along with a number of autopsy studies in the civilian population provided additional evidence that the onset of atherosclerosis may occur at an early age," according to background information in the article. Since the publication of these studies, health policies have been implemented to reduce the risk of cardiovascular disease associated with risk factors such as hypertension, diabetes, cholesterol, and smoking.

Bryant J. Webber, M.D., of the Uniformed Services University of the Health Sciences, Bethesda, Md., and colleagues conducted a study to assess the prevalence of atherosclerosis in the U.S. armed forces. The study included all U.S. service members who died of combat or unintentional injuries in support of Operations Enduring Freedom and Iraqi Freedom/New Dawn between October 2001 and August 2011 and whose cardiovascular autopsy reports were available at the time of data collection in January 2012. Prevalence of atherosclerosis was analyzed by vario
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Contact: Sharon Willis
sharon.willis@usuhs.edu
301-295-3578
JAMA and Archives Journals
Source:Eurekalert

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