Navigation Links
Automating laboratory-on-a-chip to cut healthcare costs
Date:6/16/2014

RIVERSIDE, Calif A research team at the University of California, Riverside has created a computer programming language that will automate "laboratory-on-a-chip" technologies used in DNA sequencing, drug discovery, virus detection and other biomedical applications.

A laboratory-on-a-chip is a device that integrates laboratory functions on a chip that is only millimeters or centimeters in size. The technology allows for the automation and miniaturization of biochemical reactions. It has the potential and to improve and reduce the cost of healthcare.

"If you think of the beginning of computers they were basically tools to automate mathematics," said Philip Brisk, an assistant professor in the Department of Computer Science and Engineering at UC Riverside's Bourns College of Engineering. "What are we are creating is devices that could automate chemistry in much the same way."

The most recent laboratory-on-a-chip devices are equipped with integrated electronic sensors, similar in principle to those used in today's smart phones and tablet PCs. These sensors enable scientists and health care professionals working with the devices to analyze the sensor data to make informed decisions about future analyses to perform.

Brisk and his research team are funneling the sensor data into a computer, facilitating automated decision making, rather than employing a human-in-the-loop.

"We are really trying to eliminate as much human interaction as possible," Brisk said. "Now, you have a chip, you use it and then you analyze it. Through automation and programmability, you eliminate human error, cuts costs and speed up the entire process."

Brisk's findings were recently published in a paper, "Interpreting Assays with Control Flow on Digital Microfluidic Biochips," in ACM Journal on Emerging Technologies in Computing Systems.

There were two co-authors: Daniel Grissom, one of Brisk's Ph.D. students; and Christopher Curtis, who worked with Brisk for three years as an undergraduate and plans to return as a Ph.D. student in the fall.

The team started with an existing biological programming language, BioCoder, developed by Microsoft's research office in India. It was originally created to improve the reproducibility and automation of biology experiments by using a programming language to express the series of steps taken.

The UC Riverside team modified BioCoder to process sensor feedback in real-time. Using a software simulator to mimic the behavior of a laboratory-on-a-chip, they proved it works. Now, in conjunction with William Grover, an assistant professor of bioengineering at UC Riverside, they plan to build a prototype chip that can be used for real world applications.

This research is supported by the National Science Foundation under grant CNS-1035603, an NSF Graduate Research Fellowship awarded to Grissom, and a UC Riverside Dissertation Year Fellowship, also awarded to Grissom, who completes his Ph.D. in June, 2014.

Brisk was also recently awarded a five-year, $493,645 National Science Foundation CAREER grant for related research to apply semiconductor design automation and layout principles to laboratory-on-a-chip technology.


'/>"/>

Contact: Sean Nealon
sean.nealon@ucr.edu
951-827-1287
University of California - Riverside
Source:Eurekalert  

Related medicine news :

1. NetPlus to Give Highly Anticipated Session on Automating VoIP & UC Transitions at IAUG Converge2013 on Monday, June 3rd
2. Freeslate Launches New CM Protégé Bioformulation Assessment Systems, Automating Visible Particle Detection, pH, and Viscosity Measurements
3. Weill Cornell Medical College establishes Center for Healthcare Informatics and Policy
4. Coral Calcium Company Announces New Offer Amidst Supreme Court Healthcare Decisions
5. Healthcare researchers recognized at SingHealth Duke-NUS Scientific Congress 2012
6. Daily disinfection of isolation rooms reduces contamination of healthcare workers hands
7. Health inequalities could be reduced by more effective healthcare, says new study
8. Healthcare ethics consultants share lessons learned
9. Kessler Foundation stroke expert receives $145,000 grant from Healthcare Foundation of New Jersey
10. Social environmental factors affect rehospitalization risk in home healthcare patients
11. TGen, Scottsdale Healthcare lead worldwide study of new drug for patients with pancreatic cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Automating laboratory-on-a-chip to cut healthcare costs
(Date:6/24/2016)... , ... June 24, 2016 , ... People across the ... Genome magazine’s Code Talker Award, an essay contest in which patients and their families ... to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & ... (TGIG), has initiated cultivation and processing operations at its production facility, and opened ... , Puradigm is the manufacturer of a complete system of proactive air and ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors ... on June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, ... to helping service members that have been wounded in battle and their families. Venture ...
(Date:6/24/2016)... ... June 24, 2016 , ... Finally, a bruise cream that ... dermaka cream can be incorporated into the post-surgical treatment plans of a variety of ... , dermaka cream is very effective for bruising and causes a rapid resolution of ...
(Date:6/24/2016)... New York (PRWEB) , ... June 24, 2016 , ... ... marijuana patients optimize the ingestion of their medication by matching users with high quality ... users to compare pieces with no commitment. , Inhale was founded by two brothers, ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on the ... announced that patient enrollment in its ongoing randomized ... has exceeded 50% of its 24-patient target. Capricor ... the third quarter of 2016, and to report ...
(Date:6/23/2016)... BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a ... second affiliate in Latin America . ... ... ... ...
(Date:6/23/2016)... , June 23, 2016  Experian ... integrating and transforming the patient payment and ... several innovative new products and services that ... its revenue cycle offerings. These award-winning solutions ... efficient workflows, remain compliant in an ever-changing ...
Breaking Medicine Technology: