Navigation Links
Automating laboratory-on-a-chip to cut healthcare costs
Date:6/16/2014

RIVERSIDE, Calif A research team at the University of California, Riverside has created a computer programming language that will automate "laboratory-on-a-chip" technologies used in DNA sequencing, drug discovery, virus detection and other biomedical applications.

A laboratory-on-a-chip is a device that integrates laboratory functions on a chip that is only millimeters or centimeters in size. The technology allows for the automation and miniaturization of biochemical reactions. It has the potential and to improve and reduce the cost of healthcare.

"If you think of the beginning of computers they were basically tools to automate mathematics," said Philip Brisk, an assistant professor in the Department of Computer Science and Engineering at UC Riverside's Bourns College of Engineering. "What are we are creating is devices that could automate chemistry in much the same way."

The most recent laboratory-on-a-chip devices are equipped with integrated electronic sensors, similar in principle to those used in today's smart phones and tablet PCs. These sensors enable scientists and health care professionals working with the devices to analyze the sensor data to make informed decisions about future analyses to perform.

Brisk and his research team are funneling the sensor data into a computer, facilitating automated decision making, rather than employing a human-in-the-loop.

"We are really trying to eliminate as much human interaction as possible," Brisk said. "Now, you have a chip, you use it and then you analyze it. Through automation and programmability, you eliminate human error, cuts costs and speed up the entire process."

Brisk's findings were recently published in a paper, "Interpreting Assays with Control Flow on Digital Microfluidic Biochips," in ACM Journal on Emerging Technologies in Computing Systems.

There were two co-authors: Daniel Grissom, one of Brisk's Ph.D. students; and Christopher Curtis, who worked with Brisk for three years as an undergraduate and plans to return as a Ph.D. student in the fall.

The team started with an existing biological programming language, BioCoder, developed by Microsoft's research office in India. It was originally created to improve the reproducibility and automation of biology experiments by using a programming language to express the series of steps taken.

The UC Riverside team modified BioCoder to process sensor feedback in real-time. Using a software simulator to mimic the behavior of a laboratory-on-a-chip, they proved it works. Now, in conjunction with William Grover, an assistant professor of bioengineering at UC Riverside, they plan to build a prototype chip that can be used for real world applications.

This research is supported by the National Science Foundation under grant CNS-1035603, an NSF Graduate Research Fellowship awarded to Grissom, and a UC Riverside Dissertation Year Fellowship, also awarded to Grissom, who completes his Ph.D. in June, 2014.

Brisk was also recently awarded a five-year, $493,645 National Science Foundation CAREER grant for related research to apply semiconductor design automation and layout principles to laboratory-on-a-chip technology.


'/>"/>

Contact: Sean Nealon
sean.nealon@ucr.edu
951-827-1287
University of California - Riverside
Source:Eurekalert  

Related medicine news :

1. NetPlus to Give Highly Anticipated Session on Automating VoIP & UC Transitions at IAUG Converge2013 on Monday, June 3rd
2. Freeslate Launches New CM Protégé Bioformulation Assessment Systems, Automating Visible Particle Detection, pH, and Viscosity Measurements
3. Weill Cornell Medical College establishes Center for Healthcare Informatics and Policy
4. Coral Calcium Company Announces New Offer Amidst Supreme Court Healthcare Decisions
5. Healthcare researchers recognized at SingHealth Duke-NUS Scientific Congress 2012
6. Daily disinfection of isolation rooms reduces contamination of healthcare workers hands
7. Health inequalities could be reduced by more effective healthcare, says new study
8. Healthcare ethics consultants share lessons learned
9. Kessler Foundation stroke expert receives $145,000 grant from Healthcare Foundation of New Jersey
10. Social environmental factors affect rehospitalization risk in home healthcare patients
11. TGen, Scottsdale Healthcare lead worldwide study of new drug for patients with pancreatic cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Automating laboratory-on-a-chip to cut healthcare costs
(Date:1/14/2019)... ... ... Yes, the Millennials love their Bluetooth earbuds and Alexa smart speakers. But according ... is also finding a home in senior living communities. , The 2018 Active-Aging ... organizations that work with older adults about their adoption of technology over a time ...
(Date:1/14/2019)... ... , ... Trees can be overweight too! Giroud Tree and Lawn ... is a great time to clean things up on the property! , Health and ... during windy or icy storms. The crown of the tree should be pruned to ...
(Date:1/13/2019)... ... January 12, 2019 , ... ... (YPC) in conjunction with Temple University hosted a continuing education (CEU) event entitled, ... The event aimed to create a series of talks to help develop ...
(Date:1/11/2019)... ... 2019 , ... Ms. Barrios, a first generation immigrant from ... Andrews and others engaged in a systematic pattern of discrimination against Latina and ... race and by the color of their skin, and directed Ms. Barrios, a ...
(Date:1/10/2019)... ... January 10, 2019 , ... Net-Translators, an ... with MD101, a regulatory consulting company that serves the medical industry. The companies ... companies in the medical device and healthcare industries. Based in France, they join ...
Breaking Medicine News(10 mins):
(Date:1/15/2019)... ... January 15, 2019 , ... ... screening, compliance and credentialing solutions, announces it was recently acquired by Cisive, ... Cisive caters to the complex challenges and program needs of large enterprises ...
(Date:1/15/2019)... ... January 15, 2019 , ... ... penicillin allergy in their medical record, studies have shown that over 95% can ... reducing the risk of infection with dangerous resistant pathogens such as Clostridium difficile ...
(Date:1/14/2019)... , ... January 15, 2019 , ... Sigma Theta Tau ... (AJN) Book of the Year Awards. These awards are regarded as one of the ... 49th year, the AJN Book of the Year competition has recognized Sigma for the ...
Breaking Medicine Technology: