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Autologous Bone Marrow Stem Cells Transplant into Parkinson's Disease Patients is Safe and May Improve Their Quality of Life

Clinical study showing a minimally invasive approach was presented in The XVIII World Congress on Parkinson’s Disease and Related Disorders of the World Federation of Neurology.

(PRWEB) March 11, 2010 -- Eight Parkinson’s Disease (PD) patients were treated with their own bone marrow stem cells (BMSC) injected via minimally invasive routes and discharged the next morning without complications.

Evaluations with UPDRS, Hoehn & Yahr scale and Schwab & England score showed encouraging improvements and the total L- dopamine dose could be decreased suggesting that stem cells may enhance endogenous dopamine synthesis. As a matter of sample, the writing test pre versus post procedure showed significant changes.

“It is high time we focused our efforts in what is possible and reachable and what suffering patients demand. Not all what is researched and developed in Petri dishes or rats can automatically be used in patients, so we should stop to augment their confusion. We expect this study in PD real patients, not in animals, draws the attention of those interested in getting clinical data since, funnily enough, there are billions of dollars spent in endless animal studies but very little in clinical ones” leader investigator Dr. Luis Geffner said.

They ought to be very cautious and prudent emphasizing that presently this is a tool that may complement standard treatments and delay the progress of both the illness and the complications of the medication currently used to treat it. PD patients should be cared comprehensively; therefore, their treatment may include physical therapies as well as optimal medication and stem cells transplant, trying to improve their independence and self-care he added.

Geffner’s team has already transplanted 147 patients suffering from different illnesses or trauma states and many of them have been followed up 5 years showing that autologous adult BMSC neither provoke tumors, immunologic rejection, pain, infections nor arise ethical or religious controversies. That is why they stand to push these investigations forward.

This clinical study Transplant of Autologous Bone Marrow Stem Cells into Parkinson’s Disease Patients Is Safe And May Improve Their Quality Of Life by Geffner L et al was shown in Miami on December 15th, 2009 in the XVIII World Congress on Parkinson’s Disease and Related Disorders organized by the World Federation of Neurology and published in December 2009 issue of Parkinson’s Disease and Related Disorders journal.

Dr. Geffner has been working in the field of clinical application of stem cells in many illnesses and conditions and is author of several papers, lecturer in many meetings, consultant for some biological laboratories and has founded the stem cells research in Ecuador in July 2004.

He is in charge of Stem Cells Ecuador, Guayaquil, Ecuador ( and he and his team expect to have new data to publish shortly not only in PD but also in several programs that they are developing in the regenerative medicine field.


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