Navigation Links
Autoimmune Woes May Raise Risk for Lung Clots

FRIDAY, Nov. 25 (HealthDay News) -- Patients hospitalized for autoimmune disorders, like rheumatoid arthritis or Crohn's disease, may be at greater risk for a life-threatening pulmonary embolism, a clot in a main artery of the lung, a new study finds.

Reporting online Nov. 25 in The Lancet, researchers warned that steps should be taken to prevent this condition among patients admitted to the hospital for autoimmune diseases.

In conducting the study, researchers analyzed data on more than 500,000 patients admitted to the hospital in Sweden for one of 33 autoimmune diseases, which can also include Grave's disease, Hashimoto's thyroiditis and chronic rheumatic heart disease.

The team, led by Dr. Bengt Zoller of Malmo University Hospital in Sweden, found the overall risk of pulmonary embolism in the 12 months following hospitalization to be six times higher for patients with autoimmune diseases than for those without this type of disorder.

They noted that all of the 33 autoimmune disorders included in the study were associated with a significantly higher risk of pulmonary embolism, although the most notable increases were associated with immune thrombocytopenic purpura, a clotting disorder, which carried an 11-fold increased risk; polyarteritis nodosa, a form of vasculitis (13 times the risk); and polymyositis, which involves chronic muscle inflammation (16 times the risk).

The rise in risk did decrease over time, however. Between one and five years after hospitalization, overall risk dropped to a 50 percent increased risk for those with autoimmune disorders, the researchers found. The risk dropped even further, to 15 percent five to 10 years after admission, and fell to just 4 percent after 10 years or more.

The researchers pointed out the risks were the same for men and women, and did not vary across age groups.

Zoller and colleagues said in a journal press release that preventive measures against pulmonary embolism "could be warranted in patients admitted with autoimmune disorders or at least for those disorders for which the risk of pulmonary embolism was very high. Further studies are needed to assess the potential usefulness of such treatment."

In a journal commentary, Dr. Carani B Sanjeevi, of the Karolinska Institute and Karolinska University Hospital in Stockholm, said that a "clear link is shown between thrombosis and inflammation" in the study. She agreed that "anti-inflammatory drugs and thromboprophylaxis [prevention of clots] should be considered to treat inflammation associated with autoimmune disorders, particularly in those admitted to hospital."

Sanjeevi added that more research is needed to investigate the link between inflammation and pulmonary embolism.

More information

The U.S. National Institutes of Health provides more information on autoimmune diseases.

-- Mary Elizabeth Dallas

SOURCE: The Lancet, news release, Nov. 25, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Nobel Laureate Bruce Beutler on molecular sensors as a trigger for autoimmune disease
2. T cells making brain chemicals may lead to better treatments for inflammation, autoimmune diseases
3. Mechanism discovered for health benefit of green tea, new approach to autoimmune disease
4. Discovery could change the way doctors treat patients with cancer and autoimmune diseases
5. New evidence that chronic ulcerative stomatitis is an autoimmune disease
6. Accurate interpretation of antinuclear antibodies test key to confirming autoimmune disease
7. Study shows vitamin D deficiencies may impact onset of autoimmune lung disease
8. Joint pain linked to breast cancer drug not inflammatory arthritis or autoimmune disease
9. National Jewish Health receives patent for diagnostic method of autoimmune chronic urticaria
10. A discovery by Dr. Andre Veillettes team could impact the treatment of autoimmune diseases
11. Gene Mutations Offer Clues to Autoimmune Disorders
Post Your Comments:
Related Image:
Autoimmune Woes May Raise Risk for Lung Clots 
(Date:11/25/2015)... ... , ... Beddit® has launched a new Android app for use ... a more intuitive SleepScore™ that rates sleep quality on a 100-point scale and makes ... by a proprietary algorithm. Beddit analyzes the data to provide an easy to understand ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... provide scholarships for people struggling with eating disorders as a result of the ... second annual event, held at Fox Run Golf Club in Eureka, will help ...
(Date:11/25/2015)... ... 2015 , ... Many people know of the common symptoms of low thyroid ... skin. But many people who find their cholesterol levels and weight are creeping up ... especially if they don’t have any of the other symptoms. , Thyroid hormone plays ...
(Date:11/24/2015)... ... 2015 , ... Genesis Chiropractic Software helps practice owners automate ... between the practice owner and the patient that automatically manages all five aspects ... Click here to learn more. , According to Dr. Brian ...
(Date:11/24/2015)... Dallas, Texas (PRWEB) , ... November 24, 2015 , ... ... of all charitable donations are made in the last five weeks of the year ... #GivingTuesday was created in 2012 to connect the nation’s charities with those individuals who ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... 2015 Research and Markets ( ) ... - Global Forecast to 2020" report to their ... for 37.21% of the total market share in 2014. ... region is projected to growth at the highest CAGR ... primarily to the fast growing water, industrial gas treatment, ...
(Date:11/24/2015)... 25, 2015 WuXi PharmaTech (Cayman) Inc. ("WuXi" ... open-access R&D capability and technology platform company serving the ... China and the ... extraordinary general meeting of shareholders held today, the Company,s ... and approve the previously announced agreement and plan of ...
(Date:11/24/2015)... N.C. , Nov. 24, 2015  In the ... projects in an effort to quickly uncover new insights, ... --> --> However, ... a market research project and ensure that all rules ... and industry standards. Another major barrier to efficiently launching ...
Breaking Medicine Technology: