Navigation Links
Autoantibodies and neuropsychiatric events in lupus
Date:2/27/2008

Medicine at Dalhousie University in Halifax, Nova Scotia, and supported in part by grants from the Canadian Institutes of Health Research and the Lupus Foundation of America, the study focused on 412 SLE patients recruited from 18 treatment centers. Over 87 percent of the subjects were women, ranging in age from 34 to 58 and representing diverse ethnic backgrounds -- Hispanic, Asian, black, and white. At the time of enrollment, the mean disease duration was only 5 months. Patients were evaluated to identify features of 19 NP syndromes, based on the American College of Rheumatology case definitions, within a 21-month window around the time of SLE diagnosis. Grouped into central and peripheral nervous system syndromes for analysis, the NP events included headaches, mood disorders, anxiety disorder, cerebrovascular disease, cognitive dysfunction, seizure disorder, acute confusional state, aseptic meningitis, movement disorder, Guillian-Barr syndrome, and psychosis. To determine the presence of telltale lupus autoantibodies, blood and plasma samples from each subject were analyzed in the research laboratory of Dr. Joan Merrill, a Rheumatologist and Chief of the Department of Clinical Pharmacology at the Oklahoma Medical Research Foundation and a co-investigator in the study.

Within the study window, 133 of the 412 patients (32.3 percent) had at least one NP event and 47 (11.4 percent) had two or more events. In total, the events encompassed 14 of the 19 recognized NP syndromes. The proportion of NP events directly attributed to SLE varied from 15 percent (32 of 214) to 36 percent (77 of 214), depending on the attribution model used. Testing for autoantibodies uncovered an association between anti-ribosomal P antibodies and psychosis. Seven patients had psychosis that was attributed to SLE and nearly half of these patients had anti-P antibodies. In addition, the presence of another lupus antibody called lupus anticoagulant was linked to cerebrovascul
'/>"/>

Contact: Amy Molnar
amolnar@wiley.com
Wiley-Blackwell
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Antioxidants show no clear benefit against cardiovascular events, death in high-risk women
2. Mega Events in September Allow Heart Health Campaign to Reach Tens of Thousands of Hispanics During Cholesterol Awareness Month
3. The National Center for Missing & Exploited Children, Wal-Mart, and Abbott Host Child Safety Events
4. Study shows adverse drug events reported to the FDA have significantly increased
5. American Heart Association Surgical Supplement Journal Report: Appropriate Hospital Discharge System Can Prevent Future Cardiac Events
6. Joint NJ/NY Rally for Addiction Recovery to Be Hub of Events Nationwide
7. Mega Events in September, Including Chicago Event This Sat./Sun., Allow Heart Health Campaign to Reach Tens of Thousands of Hispanics During Cholesterol Awareness Month
8. Weekly dose of osteoporosis drug prevents bone loss after breast cancer treatment
9. Researchers at IRB Barcelona discover one of the mechanisms that prevents the spread of colon cancer
10. Sallie Mae Employees Receive Award for Largest National Team at Lance Armstrong Foundation Fundraising Events
11. Fewer adverse cardiac events at one year
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... Texas (PRWEB) July 22, 2014 ... the process of deploying one of the largest physician-centric ... Network ( MHMD ) in Houston. , Created by ... M.D, the DocbookMD application will be embedded into MHMD’s ... “MHMD searched for the best technology to put this ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 The market ... increase in size through 2022, according to new industry ... their appearance can benefit from a new guide published ... for women is now available at http://cherrynews.com/best-nourishing-eye-serum . ... includes instant links to many of the top skin ...
(Date:7/22/2014)... Obtaining a bachelor’s degree in nursing just ... hands-on medical experience. The School of Nursing at The ... launch of an accelerated nursing degree program that provides ... the UNCG Veterans Access Program (VAP), will start January ... some prior college credit, veterans who are RNs can ...
(Date:7/22/2014)... 22, 2014 Mona Khan Company today ... August 15th & 16th, 2014, at the Blanks Studio ... and nationally accredited Bollywood workout was launched in the ... globally appealing Bollywood culture, Bombay Jam® is a dance-based ... follow and designed with authentic Bollywood flavor. Instructor trainings ...
(Date:7/22/2014)... Beach, FL (PRWEB) July 22, 2014 ... that they are now an authorized Daikin comfort pro ... and install Daikin indoor heating and cooling system equipment. ... each one is thoroughly reviewed before being approved. , ... an innovator in the Split System Air Conditioning Market. ...
Breaking Medicine News(10 mins):Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 2Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 3Health News:Memorial Hermann Physician Network Launches Physician Mobile Communication Solution Throughout Houston 4Health News:Eye Serum Review for Women: New Guide Published Online by Top Review Website 2Health News:UNCG School of Nursing Fast-Tracks Medically Trained Veterans 2Health News:Mona Khan Company Announces Bombay Jam® Instructor Certification in Los Angeles in August 2014 2Health News:Mona Khan Company Announces Bombay Jam® Instructor Certification in Los Angeles in August 2014 3Health News:Air Conditioning & Heating Inc. Now an Authorized Daikin Comfort Pro Dealer 2
... say , MONDAY, Aug. 17 (HealthDay News) -- The first ... has been identified by U.S. researchers. , The new marker ... a T -- in a segment of DNA near the ... They found it by studying the DNA of 1,671 people ...
... First ever-activist toolkit included with an e-book using interactive iPhone technology. ... 17 Former Vermont Governor and DNC Chairman Emeritus Howard Dean ... empower grassroots activism. Dean has teamed up with Vermont-based progressive publisher ... REAL HEALTHCARE REFORM: How We Can Achieve Affordable Medical Care for ...
... , SANTA MONICA, Calif., Aug. 17 Cord Blood ... cell preservation company ( http://www.cord b lood-america.com ... to families nationwide and internationally, said today that its 10Q filing ... of 2009 shows a significantly improved balance sheet. , , ...
... , ... it’s designed to give prospective patients an idea of what the future can hold. Dr. ... plastic surgery in Dallas a view of what they think would look best for ... room. , ...
... ... ... 17, 2009 -- SuperSlow® Zone of Greater Houston has opened its doors to ... 200 provides a one-on-one efficient, effective workout in a cool (68°), studio environment with state-of-the-art ...
... ... databases enable researchers to quickly and effectively use these invaluable resources. , ... Seattle WA (PRWEB) August 17, 2009 -- ... National Cancer Institute,s Cancer Genome Anatomy Project, or CGAP. The Madeline 2.0 Pedigree Drawing ...
Cached Medicine News:Health News:Genetic Discovery May Improve Hepatitis C Treatment 2Health News:Howard Dean and Chelsea Green Publishing Utilize iPhone Technology to engage and Mobilize Americans in Healthcare Reform Debate. 2Health News:Howard Dean and Chelsea Green Publishing Utilize iPhone Technology to engage and Mobilize Americans in Healthcare Reform Debate. 3Health News:Howard Dean and Chelsea Green Publishing Utilize iPhone Technology to engage and Mobilize Americans in Healthcare Reform Debate. 4Health News:Cord Blood America Says Balance Sheet Significantly Strengthened in 2009 2Health News:Cord Blood America Says Balance Sheet Significantly Strengthened in 2009 3Health News:Dr. Jack P. Gunter Offers 3D Imaging for Dallas, Texas Plastic Surgery Patients 2Health News:Dr. Jack P. Gunter Offers 3D Imaging for Dallas, Texas Plastic Surgery Patients 3Health News:Dr. Jack P. Gunter Offers 3D Imaging for Dallas, Texas Plastic Surgery Patients 4Health News:SuperSlow Zone Opens in Bunker Hill Village 2Health News:New Online Tutorials for Madeline 2.0 and CGAP from OpenHelix 2Health News:New Online Tutorials for Madeline 2.0 and CGAP from OpenHelix 3
(Date:7/22/2014)... 22, 2014  PuraMed BioScience®, Inc., (OTCBB: PMBS), ... medicinal and healthcare products, announced today that the ... Aid. "We are pleased to sponsor ... CEO and Chairman of PuraMed BioScience. "Research shows ... zones experience migraines much more frequently than the ...
(Date:7/22/2014)... , July 22, 2014 /PRNewswire-iReach/ -- Reproductive ... New York ), a nationally and internationally-recognized ... patients requiring reproductive assistance, is pleased to announce a ... and Compassionate Care Programs to recognize the sacrifices made ... The Compassionate Corps Program will allow qualifying veterans ...
(Date:7/22/2014)... , July 22, 2014 WuXi PharmaTech (Cayman) ... and medical device R&D outsourcing company with operations in ... , today announced that it will release financial results ... Stock Exchange closes on Wednesday, August 13, 2014 (which will ... release will be available on the investor relations section of ...
Breaking Medicine Technology:PuraMed BioScience Partners with Operation Troop Aid to Sponsor Care Packages 2PuraMed BioScience Partners with Operation Troop Aid to Sponsor Care Packages 3Reproductive Medicine Associates of New York Collaborates with EMD Serono to Offer Treatment Assistance to Eligible Veterans and their Spouses 2Reproductive Medicine Associates of New York Collaborates with EMD Serono to Offer Treatment Assistance to Eligible Veterans and their Spouses 3WuXi PharmaTech Schedules Second-Quarter 2014 Earnings Release 2
... is an intracorporeal electrokinetic lithotripter particularly ... VIBROLITH guarantees satisfaction in application to ... gall bladder and salivary gland stones. ... percutaneous applications. Kinetic energy transmitted by ...
Combination Ultrasonic and Pneumatic Urological Lithotriptor. Consists of four sizes of rigid pneumatic probes for use in the kidney, ureter and bladder....
... Multiline offers an ideal combination of ... easy and effective treatment of urinary ... wide range of urological applications. ... images enabling rapid, precise stone localization. ...
... MODULITH SLX is not only one of the ... versatile medical workstation. Apart from being designed for ... in the urinary tract, the MODULITH SLX can ... endourological therapies. It is equally suitable for the ...
Medicine Products: