Navigation Links
Autoantibodies and neuropsychiatric events in lupus
Date:2/27/2008

Systemic lupus erythematosus (SLE), commonly known as lupus, can affect nearly any part of the body, including the joints, skin, kidneys, heart, nervous system, and brain. Along with joint pain, muscle pain, unexplained fever, extreme fatigue, and skin rashes, neurologic and psychiatric events often accompany this autoimmune disease. Depending on the study, between 37 and 95 percent of SLE patients experience signs and symptoms of neuropsychiatric (NP) disease. Determining the correct attribution to NP events is a challenge when managing nervous system disease in individual SLE patients, as well as a critical factor in selecting the right treatment and evaluating progress. For guidance in these decisions, doctors need reliable biomarkers -- which, as dedicated researchers know, have proven difficult to find.

Generation of specific autoantibodies is one of the lupus-specific mechanisms underlying NP disease. Attempts to investigate their biomarker potential have been limited by the wide-ranging disease severity and duration of study patients, not to mention lack of standardization in both the classification of NP events and the methodology used for autoantibody detection. With the goal of overcoming these limitations, an international research alliance called the Systemic Lupus International Collaborating Clinics (SLICC) examined the association between a panel of autoantibodies and nervous system events at the time of diagnosis of SLE. Their results, presented in the March 2008 issue of Arthritis & Rheumatism (http://www.interscience.wiley.com/journal/arthritis), indicate two compelling links: one between anti-ribosomal P (anti-P) antibodies and psychosis attributed to SLE and the other between lupus anticoagulant (LAC) and cerebrovascular disease attributed to SLE.

Led by Dr. J.G. Hanly, a Rheumatologist at the Queen Elizabeth II Health Sciences Centre and Professor of
'/>"/>

Contact: Amy Molnar
amolnar@wiley.com
Wiley-Blackwell
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Antioxidants show no clear benefit against cardiovascular events, death in high-risk women
2. Mega Events in September Allow Heart Health Campaign to Reach Tens of Thousands of Hispanics During Cholesterol Awareness Month
3. The National Center for Missing & Exploited Children, Wal-Mart, and Abbott Host Child Safety Events
4. Study shows adverse drug events reported to the FDA have significantly increased
5. American Heart Association Surgical Supplement Journal Report: Appropriate Hospital Discharge System Can Prevent Future Cardiac Events
6. Joint NJ/NY Rally for Addiction Recovery to Be Hub of Events Nationwide
7. Mega Events in September, Including Chicago Event This Sat./Sun., Allow Heart Health Campaign to Reach Tens of Thousands of Hispanics During Cholesterol Awareness Month
8. Weekly dose of osteoporosis drug prevents bone loss after breast cancer treatment
9. Researchers at IRB Barcelona discover one of the mechanisms that prevents the spread of colon cancer
10. Sallie Mae Employees Receive Award for Largest National Team at Lance Armstrong Foundation Fundraising Events
11. Fewer adverse cardiac events at one year
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2015)... Clarkston, Metamora, Michigan (PRWEB) May 03, 2015 ... ‘Like’ mark on their Facebook page. , ... patients on the many services the Practice has, it’s ... current events. , Women’s Excellence has a very strong ... +, Pinterest, Instagram and You Tube. , Women’s ...
(Date:5/3/2015)... Bubbly Walrus ” was featured on NewsWatch as part of ... and coolest applications on the market for iOS, Android, and ... conducted the app review and shared with viewers how this ... to play on smartphones are the ones that get users ... a video game that just absorbs attention, why not exercise ...
(Date:5/3/2015)... LOUIS, Missouri (PRWEB) May 03, 2015 ... international business that will directly impact your career? ... is designed for dynamic leaders in multinational companies ... multinational company. In a changing global landscape, differences ... negotiations and relationships. The EMIB program develops the ...
(Date:5/3/2015)... Hanover, MA (PRWEB) May 03, 2015 It is ... 3rd Annual Brain Aneurysm Walk in Memory of Lissa Anne Been ... of Lissa organized this great family-friendly event to honor her loving ... since its inception. , Just having turned 37, Lissa suffered ... Lissa passed away on August 24, 2012. This event is designed ...
(Date:5/2/2015)... Ticket Down has secured additional inventories of authentic ... event today, Saturday, May 2nd at the MGM Grand Garden ... able to secure tickets for both the actual fight and ... have wanted for more than five years was finally been ... step inside the ring to fight Manny “Pac-Man” Pacquiao in ...
Breaking Medicine News(10 mins):Health News:An Application to Have Fun with Mathematics Was Featured on NewsWatch Television 2Health News:The Saint Louis University's Master of International Business Is Now Enrolling For Fall 2015 2Health News:Renowned Brain Aneurysm Foundation to Benefit from Arnold, Missouri’s 3rd Annual Brain Aneurysm Walk in Memory of Lissa Anne Been 2Health News:Cheap Floyd Mayweather vs. Manny Pacquiao Tickets: Ticket Down Has Last Minute Tickets for Mayweather vs. Pacquiao at the MGM Grand Garden Arena in Las Vegas 2Health News:Cheap Floyd Mayweather vs. Manny Pacquiao Tickets: Ticket Down Has Last Minute Tickets for Mayweather vs. Pacquiao at the MGM Grand Garden Arena in Las Vegas 3
... Supervised exercise was shown to be more effective than ... with peripheral artery disease. The findings from a national ... Association Scientific Sessions meeting. Rhode Island Hospital is one ... Peripheral artery disease (PAD) is a condition in ...
... TUESDAY, Nov. 15 (HealthDay News) -- Entering adulthood in a place ... 21, seems to put women, but not men, at a long-term ... "We want to make sure people know all of the consequences ... an assistant professor in the department of psychiatry at Washington University ...
... News) -- Scientists who identified a gene linked to ... targeted treatments for anxiety disorders. The researchers assessed ... called 7q11.23 duplication syndrome (Dup7q11.23) and Williams-Beuren syndrome (WBS). ... anxiety and specific phobias. It,s caused by extra copies ...
... About half of male breast cancer patients who take the ... effects such as weight gain and sexual dysfunction, which prompts ... to researchers at The University of Texas MD Anderson Cancer ... date of how the estrogen-blocking drug is tolerated in men ...
... have found a way to load more than 2 million ... The breakthrough could speed development of cancer treatments that would ... the inside. The research appears online this week in ... "The breast cancer cells that we studied were so laden ...
... A potential breakthrough in treating late-stage ovarian cancer has ... a peptide that shrinks advanced tumours and improves survival ... "We,re extremely excited about this," said Jim Petrik, a ... who conducted the research with PhD student Nicole Campbell. ...
Cached Medicine News:Health News:Exercise may be better than stents for PAD patients 2Health News:Higher Legal Drinking Age May Mean Safer Lives for Women 2Health News:Higher Legal Drinking Age May Mean Safer Lives for Women 3Health News:Gene Linked to Separation Anxiety 2Health News:Tamoxifen causes significant side effects in male breast cancer patients 2Health News:Tamoxifen causes significant side effects in male breast cancer patients 3Health News:Rice chemists cram 2 million nanorods into single cancer cell 2Health News:Discovery may help fight late-stage ovarian cancer 2
(Date:5/1/2015)... , May 1, 2015  An effective advisory ... provide non-binding but informed guidance to pharmaceutical organizations ... on investment, it is important for leaders to ... resources. Research and consulting leader ... assist pharmaceutical and medical device executives in identifying ...
(Date:5/1/2015)... /PRNewswire/ --Research and Markets ( http://www.researchandmarkets.com/research/vzcw2v/americas_clinical ) ... Analyzer Market by Product, by End-Users - Forecast to 2019" ... Chemistry Analyzers market is estimated to grow at a CAGR ... U.S., Canada , Mexico ... (RoA) are covered in this report. The Americas ...
(Date:5/1/2015)... , May 1, 2015 Following yesterday,s release of ... D, here are five things you need to know: ... market-based structure is unique among government programs. ... D is different than other parts of Medicare and other ... that submit bids to offer prescription drug benefits to enrollees. ...
Breaking Medicine Technology:New Study Presents Insights to Advisory Board Effectiveness in the Pharmaceutical Sector 2Americas Clinical Chemistry Analyzer (Semi-Automated Clinical Chemistry and Fully-Automated Clinical Chemistry) Market - Forecast to 2019 25 Things to Know About the CMS Part D Data Release 25 Things to Know About the CMS Part D Data Release 3
... Spirit is the premium APAP device in ... The AutoSet algorithm responds to the patients ... flow generator stores and reports comprehensive clinical ... AutoSet devices combine integrated humidification and a ...
Paediatric tubes have decreased sample volumes and are ideal for small childrens' veins and geriatric patients....
... System provides the capability to ... middle of surgery while retaining ... incision. The system is also ... for large patients while remaining ...
These retractors, made of rugged Noryl® resin, are pre-sterilized and packaged singly in double peel-pouches for easy delivery to the sterile surgical field....
Medicine Products: