Navigation Links
Autoantibodies and neuropsychiatric events in lupus
Date:2/27/2008

Systemic lupus erythematosus (SLE), commonly known as lupus, can affect nearly any part of the body, including the joints, skin, kidneys, heart, nervous system, and brain. Along with joint pain, muscle pain, unexplained fever, extreme fatigue, and skin rashes, neurologic and psychiatric events often accompany this autoimmune disease. Depending on the study, between 37 and 95 percent of SLE patients experience signs and symptoms of neuropsychiatric (NP) disease. Determining the correct attribution to NP events is a challenge when managing nervous system disease in individual SLE patients, as well as a critical factor in selecting the right treatment and evaluating progress. For guidance in these decisions, doctors need reliable biomarkers -- which, as dedicated researchers know, have proven difficult to find.

Generation of specific autoantibodies is one of the lupus-specific mechanisms underlying NP disease. Attempts to investigate their biomarker potential have been limited by the wide-ranging disease severity and duration of study patients, not to mention lack of standardization in both the classification of NP events and the methodology used for autoantibody detection. With the goal of overcoming these limitations, an international research alliance called the Systemic Lupus International Collaborating Clinics (SLICC) examined the association between a panel of autoantibodies and nervous system events at the time of diagnosis of SLE. Their results, presented in the March 2008 issue of Arthritis & Rheumatism (http://www.interscience.wiley.com/journal/arthritis), indicate two compelling links: one between anti-ribosomal P (anti-P) antibodies and psychosis attributed to SLE and the other between lupus anticoagulant (LAC) and cerebrovascular disease attributed to SLE.

Led by Dr. J.G. Hanly, a Rheumatologist at the Queen Elizabeth II Health Sciences Centre and Professor of
'/>"/>

Contact: Amy Molnar
amolnar@wiley.com
Wiley-Blackwell
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Antioxidants show no clear benefit against cardiovascular events, death in high-risk women
2. Mega Events in September Allow Heart Health Campaign to Reach Tens of Thousands of Hispanics During Cholesterol Awareness Month
3. The National Center for Missing & Exploited Children, Wal-Mart, and Abbott Host Child Safety Events
4. Study shows adverse drug events reported to the FDA have significantly increased
5. American Heart Association Surgical Supplement Journal Report: Appropriate Hospital Discharge System Can Prevent Future Cardiac Events
6. Joint NJ/NY Rally for Addiction Recovery to Be Hub of Events Nationwide
7. Mega Events in September, Including Chicago Event This Sat./Sun., Allow Heart Health Campaign to Reach Tens of Thousands of Hispanics During Cholesterol Awareness Month
8. Weekly dose of osteoporosis drug prevents bone loss after breast cancer treatment
9. Researchers at IRB Barcelona discover one of the mechanisms that prevents the spread of colon cancer
10. Sallie Mae Employees Receive Award for Largest National Team at Lance Armstrong Foundation Fundraising Events
11. Fewer adverse cardiac events at one year
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... Marathon, FL (PRWEB) , ... July 30, 2015 ... ... streaming software, TikiLIVE, has worked to protect victims in San Diego, California’s Gaslamp ... cameras used by Gaslamp Quarter Plaza actively monitor the area for any ...
(Date:7/30/2015)... , ... July 30, 2015 , ... ... growing into one of the largest, family-owned low cost service and repair companies. ... commercial applications, as well as growing their company to meet the demands of ...
(Date:7/30/2015)... CA (PRWEB) , ... July ... ... recently released a video, “Beachside Nursing Center,” to announce its position as ... five-star ratings. Beachside's administrator and staff members support the CMS rating system, ...
(Date:7/30/2015)... , ... July 30, 2015 , ... Ross A. ... College of Medicine as Assistant Professor of Plastic Surgery. This is Dr. Clevens’ ... has worked closely with the university, developing a strong presence and a valuable mentoring ...
(Date:7/30/2015)... , ... July 30, 2015 , ... Using the latest ... and teach people more effective ways to prevent and manage major depression. , “Suicide ... fast enough, so people fall through the cracks and die needlessly everyday,” says Walker. ...
Breaking Medicine News(10 mins):Health News:Eyepartner Software Helps Victims in Gaslamp Quarter Plaza 2Health News:Eyepartner Software Helps Victims in Gaslamp Quarter Plaza 3Health News:Bill Howe Plumbing, Heating & Air Launches Online Application to Prospective Employees 2Health News:Bill Howe Plumbing, Heating & Air Launches Online Application to Prospective Employees 3Health News:Beachside Nursing Center Releases New Video 2Health News:Leading Melbourne Facial Plastic Surgeon Reappointed by UCF 2Health News:Leading Melbourne Facial Plastic Surgeon Reappointed by UCF 3Health News:Happiness Expert Develops Pioneering Online Tools for Sufferers of Major Depression, and Who may be Suicidal 2Health News:Happiness Expert Develops Pioneering Online Tools for Sufferers of Major Depression, and Who may be Suicidal 3
... some 200 million individuals worldwide and is fast becoming the ... more than 22 million people have diabetes, which is the ... , Now, thanks to a $2.5 million ... of scientists will be trained in multiple disciplines to fight ...
... million to continue to fight preventable blindnessTuesday, January ... BrookOAK BROOK, Ill., Jan. 26 Former U.S. ... Sight" statue on Tuesday, January 27, 2009, at ... Oak Brook. The statue symbolizes Lions Clubs International ...
... Calif., Jan. 26, 2009 Astronauts spending months in ... risk for fractures later in life. , UC Irvine ... astronauts who spent four to six months on the ... hipbone strength decreased 14 percent. Three astronauts experienced losses ...
... worse on cognition tests, study found , , MONDAY, Jan. 26 ... average blood glucose (sugar) levels may be linked to lower ... that patients with higher levels of hemoglobin A1C (a measure ... had significantly worse results while doing cognitive tasks that tested ...
... type of change that has come to Washington is ... Medicine, the leader in prevention.(Logo: http://www.newscom.com/cgi-bin/prnh/20080506/NETU129LOGO ... to our capital, the time is ripe to bring ... care," said Christopher Fey, Chairman and CEO of U.S. ...
... of philanthropic donor-advised funds and the Myeloma Research Foundation ... Project", an ongoing research initiative at the Institute for ... CALOS ANGELES, Jan. 26 IMBCR,s "Cure Myeloma Project" ... for multiple myeloma, a blood cancer that resides in ...
Cached Medicine News:Health News:From molecules to populations: Fighting the epidemics of obesity and diabetes 2Health News:From molecules to populations: Fighting the epidemics of obesity and diabetes 3Health News:Former U.S. President Jimmy Carter Dedicates 'Gift of Sight' Statue in Recognition of Lions' Blindness Prevention Efforts 2Health News:Former U.S. President Jimmy Carter Dedicates 'Gift of Sight' Statue in Recognition of Lions' Blindness Prevention Efforts 3Health News:Astronauts on International Space Station lose alarming amounts of hipbone strength 2Health News:Higher Blood Sugar Could Impair Thinking 2Health News:U.S. Preventive Medicine Recommends Changing CDC Name to Centers for Disease Prevention and Control 2Health News:1.2 Million Dollars Recently Awarded to Institute for Myeloma and Bone Cancer Research 2
(Date:7/30/2015)... , July 30, 2015 Tianyin Pharmaceutical ... pharmaceutical company that specializes in the patented biopharmaceutical, modernized ... ingredients (API), provided updates regarding the notice it received ... (the "Exchange") indicating that the Company was below certain ... in Sections 134 and 1101 of the NYSE MKT ...
(Date:7/30/2015)... , July 30, 2015  Growth of the ... as they bring former prescription users to the OTC ... Kline forecasts robust Rx-to-OTC switch activity over the ... emerging along with many new brands entering the market ... over the next five years (even those with low ...
(Date:7/30/2015)... FAIRFIELD, N.J. , July 30, 2015 /PRNewswire/ ... Ferrer, completed the second Phase III clinical study ... development for impetigo.  Medimetriks owns the exclusive U.S. ... The global trial, conducted at 44 centers with ... and pediatric patients aged 2 months and older ...
Breaking Medicine Technology:TPI Provides Update Regarding Non-Compliance with NYSE MKT Continued Listing Requirements 2Rx-to-OTC Switches -- Game Changers for the U.S. OTC Drugs Market through 2019, Sees Kline 2Rx-to-OTC Switches -- Game Changers for the U.S. OTC Drugs Market through 2019, Sees Kline 3Medimetriks Pharmaceuticals, Inc. Announces Completion of the Second Successful Pivotal Phase III Study for Ozenoxacin 2Medimetriks Pharmaceuticals, Inc. Announces Completion of the Second Successful Pivotal Phase III Study for Ozenoxacin 3
... /PRNewswire-Asia/ -- Chindex International, Inc. (Nasdaq: CHDX ... providing health care services in China through the operations ... primary care hospitals and affiliated ambulatory clinics, today announced ... ended December 31, 2010. Presentation of ...
... American Association for Homecare strongly endorses bipartisan legislation to ... program for home medical equipment and services (durable medical ... Glenn Thompson (R-Pa.) and Jason Altmire (D-Pa.) on March ... Bidding Act."   Tyler Wilson, president ...
Cached Medicine Technology:Chindex International, Inc. Reports Financial Results for the Three and Nine Month Period Ended December 31, 2010 2Chindex International, Inc. Reports Financial Results for the Three and Nine Month Period Ended December 31, 2010 3Chindex International, Inc. Reports Financial Results for the Three and Nine Month Period Ended December 31, 2010 4Chindex International, Inc. Reports Financial Results for the Three and Nine Month Period Ended December 31, 2010 5Chindex International, Inc. Reports Financial Results for the Three and Nine Month Period Ended December 31, 2010 6Chindex International, Inc. Reports Financial Results for the Three and Nine Month Period Ended December 31, 2010 7Chindex International, Inc. Reports Financial Results for the Three and Nine Month Period Ended December 31, 2010 8Chindex International, Inc. Reports Financial Results for the Three and Nine Month Period Ended December 31, 2010 9Chindex International, Inc. Reports Financial Results for the Three and Nine Month Period Ended December 31, 2010 10Home Medical Equipment Group Supports Bipartisan Bill to Repeal the Controversial Medicare 'Competitive' Bidding Program for Homecare 2Home Medical Equipment Group Supports Bipartisan Bill to Repeal the Controversial Medicare 'Competitive' Bidding Program for Homecare 3
This extra long 180 ul pipet tip will reach the bottom of large tubes and vials, preventing your pipettor from contacting the sample container....
Diamond Filter Tips play a critical role in preventing aerosol-borne contamination. Also available sterilized (no need to autoclave) and certified free of detectable RNase, DNase, DNA, RNA, and prote...
This tip's tight fit and MicroPoint design make it ideal for use with the Pipetman P-20. 10 L reference mark ensures consistent pipetting with low volumes....
... as both regular and filter tips. Sterilized ... more efficient sterilization and are delivered with ... of irradiation. Sterilized Diamond Tips are ready ... Diamond Tips are wrapped in medical device ...
Medicine Products: