Navigation Links
Auto-immune disease: The viral route is confirmed
Date:12/19/2012

Why would our immune system turn against our own cells? This is the question that the combined Inserm/CNRS/ Pierre and Marie Curie University/Association Institut de Myologie have strived to answer in their "Therapies for diseases of striated muscle", concentrating in particular on the auto-immune disease known as myasthenia gravis. Through the project known as FIGHT-MG (Fight Myasthenia Gravis), financed by the European Commission and coordinated by Inserm, Sonia Berrih-Aknin and Rozen Le Panse have contributed proof of the concept that a molecule imitating a virus may trigger an inappropriate immune response, causing muscular function to deteriorate. These results have been published in Annals of Neurology, accessible on line.

Myasthenia, a rare auto-immune disease

Myasthenia gravis is a rare auto-immune disease (5,000 to 6,000 patients in France) that produces muscular weakness and exhaustion. It generally affects the facial muscles first, and may then become generalised through the muscles of the limbs or the respiratory muscles, causing respiratory distress.

This is due to the production of circulating auto-antibodies that block the acetylcholine receptors (RACh), these neurotransmitters being necessary for transmitting the motor nerve signal to the neuro-muscular junction.

Could a viral infection be the origin of myasthenia?

Myasthenia is a multi-factorial disease in which environmental factors seem to play a key triggering role. Viral infections are suspected but it is hard to prove the role of a virus in triggering the condition. In fact, diagnosis of myasthenia is often made months, or even years, after the actual start of the illness when the virus is no longer detectable, even though the signature left by the virus is visible long after the infection.

Proof of the concept of a viral origin contributed by researchers

Under the European FIGHT-MG project, the team of researchers managed to d
'/>"/>

Contact: Rozen Le Panse
Rozen.lepanse@upmc.fr
33-014-077-8127
INSERM (Institut national de la sant et de la recherche mdicale)
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Multivitamins Wont Help Men Ward Off Heart Disease: Study
2. Obese Teens Face Higher Risk for Kidney Disease: Study
3. The future of diagnosing disease: New American Chemical Society Prized Science video
4. Chemical in Household Products May Be Linked to Heart Disease: Study
5. Most Prostate Cancer Patients Dont Die From the Disease: Study
6. 300,000 People in U.S. Living With Chagas Disease: Report
7. New Lawsuit on Accutane Crohn’s Disease: Severe Adverse Events
8. Sleep May Ease Symptoms of Parkinsons Disease: Study
9. Pneumococcal disease: More cases but fewer deaths
10. People with HIV hospitalized less often since combination antiretroviral drug therapy introduced
11. Adult antiviral drug effective in suppressing hepatitis B in teens
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... March 12 For Southern California residents who are looking to ... classified as obese, who have a BMI of over 40, are prime candidates for ... of lap band and gastric bypass surgery can lose anywhere ... they choose. , ...
... (IWV) will host a conference call to discuss its new health care poll Monday, March 15 at NOON ET .  The poll surveys attitudes in 35 ... ... ... ...
... year, nearly three million youths run away from home, putting themselves at a high risk for drug addiction, prostitution, disease ... the risks associated with teen homelessness and the services available to youth in crisis.   , ... ... , ...
... LLC to provide Medication Therapy Management (MTM) to City of Minneapolis employees and family members with Medica health plan coverage. ... ... , ... ...
... Day allows members of the radiation oncology treatment ... experienced Washington policymakers. Participants in this annual event ... the future of radiation oncology., ASTRO recognizes that ... in the present and future,of the specialty but ...
... cancer in one breast should have other one scanned, researchers ... are more likely to turn up undiagnosed tumors in the ... other breast, researchers report. , However, the scans are less ... "Our findings are not really surprising because we know that ...
Cached Medicine News:Health News:Dr. Feiz (drfeiz.com) Asks: What Is Better for You? Lap Band Surgery/Realize Band Surgery or Gastric Bypass Surgery 2Health News:Dr. Feiz (drfeiz.com) Asks: What Is Better for You? Lap Band Surgery/Realize Band Surgery or Gastric Bypass Surgery 3Health News:Independent Women's Voice Releases Health Care Poll 2Health News:National Safe Place Week Helps Prevent Teen Homelessness 2Health News:National Safe Place Week Helps Prevent Teen Homelessness 3Health News:National Safe Place Week Helps Prevent Teen Homelessness 4Health News:Medica Selects Fairview Pharmacy Services, LLC to Deliver Medication Therapy Management Services to City of Minneapolis Employees 2Health News:Medica Selects Fairview Pharmacy Services, LLC to Deliver Medication Therapy Management Services to City of Minneapolis Employees 3Health News:Medica Selects Fairview Pharmacy Services, LLC to Deliver Medication Therapy Management Services to City of Minneapolis Employees 4Health News:Medica Selects Fairview Pharmacy Services, LLC to Deliver Medication Therapy Management Services to City of Minneapolis Employees 5Health News:ASTRO awards 17 Advocacy Day travel grants 2Health News:MRIs May Detect Hidden Tumors in Breast Cancer Patients 2
(Date:12/15/2014)... FRESH MEADOWS, N.Y. , Dec. 15, 2014 /PRNewswire/ ... using the SPL (Structured Product Labeling) markup language standard, ... need the understanding and skills to work with the ... present a series of three webinars on the benefits ... The three one-hour webinars will be facilitated by ...
(Date:12/15/2014)... --  DaVita HealthCare Partners Inc.  (NYSE: ... most innovative health care communities, today announced that ... Research  (DCR) and  HealthCare Partners Clinical Research , will ... research and data analytics services, specifically in patients ... disease (ESRD), as well as primary care and ...
(Date:12/15/2014)... BOSTON , December 15, 2014 ... discovery and development company, is pleased to announce the ... United States relating to its GPCR-focused drug ... US significantly strengthens the global patent estate covering Heptares, ... The suite of patents recently granted by the ...
Breaking Medicine Technology:Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 2Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 3DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 2DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 3DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 4Heptares Extends Global Patent Protection for GPCR-Focused Drug Discovery Platform With Grant of Core Patents in the United States 2
... 2011 The latest developments in molecular diagnostics, personalized ... more than 1,000 pathologists gather at the Gaylord Texan ... meeting of the College of American Pathologists ... will highlight advances in digital imaging related to laboratory ...
... 22, 2011 The Specialty Pharma Association announces its Fall Conference ... 20-22, 2011, San Diego Marriott Marquis Hotel & Marina ... Robert Greenwood, RPh President ... PMP, PgMP, TSPM, ITBMC President TenStep, ...
Cached Medicine Technology:Pathologists Gather to Focus on Advances in Molecular Testing, Digital Imaging, and Biospecimens 2Pathologists Gather to Focus on Advances in Molecular Testing, Digital Imaging, and Biospecimens 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: