Navigation Links
Autism's origins: Mother's antibody production may affect fetal brain
Date:2/25/2008

The mothers of some autistic children may have made antibodies against their fetuses brain tissue during pregnancy that crossed the placenta and caused changes that led to autism, suggests research led by Johns Hopkins Childrens Center investigators and published in the February issue of the Journal of Neuroimmunology.

The causes of autism, a disorder manifesting itself with a range of brain problems and marked by impaired social interactions, communication disorders and repetitive behaviors, remain unknown for an estimated 90 percent of children diagnosed with it. Genetic, metabolic and environmental factors have been implicated in various studies of autism, a disorder affecting 1 in 150 U.S. children, according to estimates by the Centers for Disease Control and Prevention.

Now our research suggests that the mothers immune system may be yet another factor or a trigger in those already predisposed, says lead investigator Harvey Singer, M.D., director of pediatric neurology at Hopkins Childrens.

Researchers caution that the findings neednt be cause for alarm, but should be viewed instead as a step forward in untangling the complex nature of autism.

Mostly anecdotal past evidence of immune system involvement has emerged from unusual antibody levels in some autistic children and from postmortem brain tissue studies showing immune abnormalities in areas of the brain. Antibodies are proteins the body makes in response to viruses and bacteria or sometimes mistakenly against its own tissues. Yet, the majority of children with autism have no clinical evidence of autoimmune diseases, which prompted researchers to wonder whether the antibodies transferred from mother to child during pregnancy could interfere with the fetal brain directly.

To test their hypothesis, the research team used a technique called immunoblotting (or Western blot technology), in which antibodies derived from blood samples are exposed to adult
'/>"/>

Contact: Ekaterina Pesheva
epeshev1@jhmi.edu
410-516-4996
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Some cases of autism may be traced to the immune system of mothers during pregnancy
2. Mothers and Youth Sports Nationwide Push for FabricAide in Response to MRSA Threat
3. Mothers stress may increase childrens asthma
4. Smoking and depression often co-occur in new mothers
5. HIV drug resistance risk in mothers reduced by combination of common drugs
6. Overweight mothers run greater risk of having hyperactive children
7. Hip size of mothers linked to breast cancer in daughters
8. Mothers Know Best: NFL Moms Team With Eddie George to Showcase a Better Way to a Healthier Lifestyle
9. FDA Warns of Codeine Risk for Some Nursing Mothers
10. Vaccine/antibody therapy effective, milder side effects in melanoma and ovarian cancer
11. EUSA Pharma Out-Licenses Preclinical-Stage Human Antibody to GlaxoSmithKline for up to $44 Million Plus Royalties
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... May 05, 2015 Horizon Blue Cross ... strong and secure credit rating of “A” from Standard ... financials last week, the Wall Street ratings agency cited ... market position” in determining the rating and “stable” outlook. ... one of our top priorities, so we are pleased ...
(Date:5/5/2015)... York, New York (PRWEB) May 05, 2015 ... lawsuits ( http://www.testosteronelawsuithub.com/ ) filed on behalf ... complications due to their use of prescription ... in the federal multidistrict litigation underway in ... According to court documents dated May 1st, ...
(Date:5/5/2015)... 05, 2015 Sunny skies and cool temperatures ... as nearly 400 runners and walkers participated in Global Lyme ... nearly $35,000. , The 5K and 10K runs and ... disease and to raise funds for tick-borne disease research. The ... the recent merger of Lyme Research Alliance (LRA) ...
(Date:5/5/2015)... Creek, Michigan (PRWEB) May 05, 2015 In ... media outlet The Herald-Times , the Missouri State Highway ... involving Crystal Methamphetamine production or use for the second year ... meth statistics to the FBI, reported 1,469 incidents in 2014 ... into perspective, only around 2% of the US Population calls ...
(Date:5/5/2015)... The brains of people with type 1 ... slower information processing, according to research led by the ... . , The findings indicate that clinicians should ... cognitive difficulties. If progressive, these changes could influence their ... the National Institutes of Health (NIH), is ...
Breaking Medicine News(10 mins):Health News:Horizon Blue Cross Blue Shield of New Jersey Maintains “A” Credit Rating from Standard & Poor’s 2Health News:Federal Testosterone Lawsuit Defendants Recently Submitted Answers to Master Long Form Complaint 2Health News:Federal Testosterone Lawsuit Defendants Recently Submitted Answers to Master Long Form Complaint 3Health News:Federal Testosterone Lawsuit Defendants Recently Submitted Answers to Master Long Form Complaint 4Health News:1st Annual “Lyme Walk & Run” Event a Huge Success 2Health News:1st Annual “Lyme Walk & Run” Event a Huge Success 3Health News:A Forever Recovery Releases New Information on the Epidemic Rise Of Methamphetamine Abuse in Midwest America 2Health News:Accelerated Brain Aging in Type 1 Diabetes Related to Cognitive Complications 2Health News:Accelerated Brain Aging in Type 1 Diabetes Related to Cognitive Complications 3Health News:Accelerated Brain Aging in Type 1 Diabetes Related to Cognitive Complications 4
... ... plastic surgery celebrates its 10 year Anniversary. , ... (PRWEB) June 20, 2010 -- Having grown from a small internet startup ... proud to mark its 10th anniversary this summer by thanking all the clients, customers, and ...
... ... company, has announced that it will launch a host of exciting new products at V-Malaysia ... , ... QuestNet , an international direct selling and network marketing company, has announced that it ...
... ... 88-year-old woman from Brooklyn, NY, lost her life savings of $60,000 by ... was a winner when she started receiving solicitations with phrasing like “You ... claim your check” printed in large colorful fonts, along with official looking ...
... games main reasons for spike between 2008 and 2009, ... Summer activity-related head injuries appear to be on the ... and bicycling, water sports and baseball/softball are the main ... of head injury trends as they transpired between 2008 ...
... of deaths in a study of 12,000 Bangladeshis were attributable ... The large 10-year study is the first to ... its associated mortality risk, the authors said. The data, collected ... will be published early online Saturday in The Lancet ...
... terms of increased libido, studies found , FRIDAY, June 18 ... panel on Friday unanimously agreed that a pill dubbed by ... benefits to warrant approval. , Called flibanserin, the drug was ... is related to the antidepressant family and affects serotonin and ...
Cached Medicine News:Health News:Signature Forum Celebrates 10th Anniversary 2Health News:QuestNet to Launch New Consumable Products at Annual Convention 2Health News:QuestNet to Launch New Consumable Products at Annual Convention 3Health News:QuestNet to Launch New Consumable Products at Annual Convention 4Health News:Senior Citizen Defrauded By Sweepstakes Scams Wins Big With The National Telemarketing Victim Call Center And Recovers $14,000.00 2Health News:Senior Citizen Defrauded By Sweepstakes Scams Wins Big With The National Telemarketing Victim Call Center And Recovers $14,000.00 3Health News:Senior Citizen Defrauded By Sweepstakes Scams Wins Big With The National Telemarketing Victim Call Center And Recovers $14,000.00 4Health News:Bump in Head Injury Numbers Linked to Summer Play 2Health News:Deadly effect of arsenic in drinking water measured in massive study 2Health News:Deadly effect of arsenic in drinking water measured in massive study 3
(Date:5/5/2015)... Calif. , May 5, 2015  Desert Valley Medical ... times , is the first U.S. hospital to deploy ... Delivery rooms to help reduce the duration of labor and ... is shortened and the risk of caesarean birth is reduced ... However, most mothers in labor are given epidurals and ...
(Date:5/5/2015)...  IQPC,s 19 th Software Design for Medical ... the Summit Mr. Phani Bidarahalli , GM & Head ... the expert speaker faculty including senior executive from GE Healthcare, ... at The Hotel Kabuki in San Francisco ... on the event website, which can be accessed by visiting ...
(Date:5/5/2015)... -- Big Market Research presents a detailed analysis of ... , ( France , Germany , ... and Japan . Current scientific views on the ... 5-year test volume and sales forecasts by country for HAV NAT, ... Delta, HBc Ag, HBe Ag, and ALT/SGPT tests performed in the ...
Breaking Medicine Technology:Desert Valley Medical Center First to Use Leaf Patient-Wearable Technology to Help Reduce C-Sections, Speed Labor 2Desert Valley Medical Center First to Use Leaf Patient-Wearable Technology to Help Reduce C-Sections, Speed Labor 3Desert Valley Medical Center First to Use Leaf Patient-Wearable Technology to Help Reduce C-Sections, Speed Labor 4Phani Bidarahalli from Wipro to chair the upcoming 19th Software Design for Medical Devices Summit in San Francisco 22015 Opportunities in the Global Hepatitis Diagnostic Testing Market: Big Market Research 22015 Opportunities in the Global Hepatitis Diagnostic Testing Market: Big Market Research 3
... DIEGO, Jan. 10, 2011 Optimer Pharmaceuticals, Inc. (Nasdaq: ... Linda Amper, Ph.D., as Senior Vice President of Human ... Economics & Outcomes Research (HEOR), and John Womelsdorf, Ph.D., ... will strengthen the management team as the Company prepares ...
... Calif., Jan. 10, 2011 OncoMed Pharmaceuticals, Inc., ... today announced that patient dosing has commenced in a Phase ... tumor cancers.   OMP-59R5 is a monoclonal antibody ... to specifically block these targets to enter human studies.  The ...
Cached Medicine Technology:Optimer Pharmaceuticals Announces Key Additions to Management Team 2Optimer Pharmaceuticals Announces Key Additions to Management Team 3Optimer Pharmaceuticals Announces Key Additions to Management Team 4OncoMed Pharmaceuticals Initiates Phase 1 Clinical Trial of Anti-Cancer Stem Cell Therapeutic OMP-59R5 2OncoMed Pharmaceuticals Initiates Phase 1 Clinical Trial of Anti-Cancer Stem Cell Therapeutic OMP-59R5 3
Full plate covers seal all 24 MicroAmp tubes...
An alternative sealing method for samples that are stored in 96-well plates after PCR. The mat is fully autoclavable and can be reused up to 50 times....
Inquire...
Pkg qty: box of 2 bags pack of 25 (Pack = Zippered Bag)...
Medicine Products: