Navigation Links
Autism Speaks awards $770,000 for gastrointestinal research in autism spectrum disorders
Date:4/13/2011

New York, N.Y. (April 14, 2011) Recognizing that gastrointestinal (GI) dysfunction affects many children and adolescents with autism spectrum disorders (ASD), Autism Speaks, the world's largest autism science and advocacy organization, today announced a major Suzanne and Bob Wright Trailblazer Award for research into the biological mechanisms of GI disorders in ASD. Paul Ashwood, Ph.D., of the M.I.N.D. Institute of UC Davis, the lead Principal Investigator and his collaborators Alessio Fasano, M.D. at University of Maryland School of Medicine, and Paul Patterson, Ph.D. of the California Institute of Technology will receive $769,943 over a two year period to investigate the underlying biology of GI dysfunction in children with ASD, and in an animal model, test a novel probiotic therapy to restore function of the GI system.

Autism Speaks recently launched its Trailblazer Awards to support highly novel "out of the box" autism-relevant research. "GI problems are a common and distressing concern for many children and adolescents with ASD and their families," explained Autism Speaks Chief Science Officer Geraldine Dawson, Ph.D. "These conditions are not only a strain on the health of the children affected, GI problems can seriously interfere with their ability to participate in and benefit from activities of daily life, education and therapeutic activities."

"This Trailblazer award provides us with a fantastic opportunity to delve deeper to understand the mechanisms that may underlie altered GI function in some children with autism," stated Paul Ashwood, Ph.D, Principal Investigator. "We will also explore the very exciting possibility that novel therapies could address this GI dysfunction in model systems."

Autism is behaviorally defined by impairments in communication, social interactions, and repetitive stereotypic behaviors. Many children with ASD also experience GI symptoms such as irregular bowel movements and abdominal pain. Several studies have described altered GI and immune function in children with ASD and GI symptoms. In these children the presence of GI symptoms is often associated with increased irritability, tantrums, aggressive behavior and sleep disturbance. For families and children with ASD, access to rigorously studied treatments for medical conditions associated with autism is a major unmet need. Autism Speaks Autism Treatment Network (ATN) provides experts in the care and management of GI problems for children with ASD and engages in clinical research. However, the underlying nature of GI dysfunction in ASD and its relationship to etiology and ASD symptoms are still poorly understood. This information is critical to developing better and more targeted treatments, so both clinical and basic research in this area is needed. To accelerate research and find answers for those who suffer with GI problems and ASD, Autism Speaks issued a special Request for Applications to stimulate research to systematically explore and better understand GI dysfunction in ASD. This new study brings together innovative and cutting-edge pilot projects that form a new synergistic and coordinated effort. The connections between irregular bowel movements, gut barrier function, gut bacteria, immune function, and abnormal behavior have as yet not been investigated in ASD. This Trailblazer Study will examine these potential links.

"This groundbreaking approach has the potential to provide insights into the pathophysiology of GI dysfunction in ASD that we believe can set the stage for larger scale studies and treatment applications," explained Autism Speaks Vice President of Clinical Programs, Clara Lajonchere, Ph.D. "We have great hopes for this collaboration because each of the researchers involved is applying his GI expertise to autism research in an unprecedented way."


'/>"/>

Contact: Jane E. Rubinstein
jrubinstein@rubenstein.com
212-843-8287
Autism Speaks
Source:Eurekalert  

Related medicine news :

1. Best Places to Live With Autism All in Major Metro Areas: Survey
2. Autism Diagnoses Still More Likely in Richer Neighborhoods
3. Gene linked to severity of autisms social dysfunction
4. Study: Socioeconomics playing reduced role in autism diagnoses
5. Evidence Weak to Support Many Medications for Autism: Study
6. Brains of People with Autism Focus More on Visual Skills
7. Interest in Toys May Predict Success of Autism Home Therapy
8. Dangerous Wandering a Lesser Known Side of Autism
9. Interest in toys predicts effectiveness of autism treatment in toddlers
10. Scientists Create Autism-Like Traits in Mice
11. Autism Speaks supports new diagnostic code for individuals with autism with history of wandering
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Autism Speaks awards $770,000 for gastrointestinal research in autism spectrum disorders
(Date:2/5/2016)... New York (PRWEB) , ... February 05, 2016 , ... ... use and find themselves having to wait longer to access the treadmills. It’s a ... New Year’s resolutions to lose weight and get in shape by joining gyms, starting ...
(Date:2/5/2016)... ... 2016 , ... Pivot Point Consulting, a leading national Healthcare ... Services for HIT Implementation Support & Staffing report with an outstanding score of ... healthcare executives, managers and clinicians representing over 4,500 hospitals and 2,500 clinics. , ...
(Date:2/5/2016)... , ... February 05, 2016 , ... Stuart Bentkover, ... technology, the PicoSure. Designed to provide the most effective tattoo removal today, Dr. Bentkover ... unmatched results. , Developed by Cynosure, the PicoSure has been approved by the Food ...
(Date:2/5/2016)... Pekin, IL (PRWEB) , ... February 05, 2016 , ... ... in disguised form as a dream. A hallmark feature of patients with eating disorders ... and needs. The eating disorder behaviors and obsessions are regarded as maladaptive means for ...
(Date:2/5/2016)... ... February 05, 2016 , ... On June 9-10, ... a continuing medical education (CME) event presented by the Association for Comprehensive Care ... first for ACCORD, whose mission is to provide education, tools, and resources to ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... WILLIAMSBURG, Va. , Feb. 5, 2016  ivWatch, a ... a Virginia Outstanding STEM Award granted by Governor Terry ... for Science Innovation on February 25th at an event to ... . The STEM award honors professionals and business that ... Logo - http://photos.prnewswire.com/prnh/20160205/330117LOGO ...
(Date:2/5/2016)... MILTON, Ontario , Feb. 5, 2016  Aralez ... business combination of POZEN Inc. ("POZEN") and Tribute Pharmaceuticals Canada ... of POZEN and shareholders of Tribute. The combined company ... specialty pharmaceutical company with operations in Canada ... the United States . Under the terms ...
(Date:2/5/2016)...  Venice,s newest laser clinic, Physicians Advanced ... kind in the area and specializes in the ... The physician-owned and operated laser clinic is taking ... with its revitalizing skin care approach, unprecedented eVisit ... technology. http://photos.prnewswire.com/prnh/20160204/329957 --> ...
Breaking Medicine Technology: