Navigation Links
Autism Consortium study in Pediatrics shows CMA finds more genetic abnormalities than current tests
Date:3/14/2010

Boston March 15, 2010 The Autism Consortium, an innovative research, clinical and family collaboration dedicated to catalyzing research and enhancing clinical care for families with autism spectrum disorders (ASDs), announced today that the results of its comparison study of genetic testing methods for autism spectrum disorders is available from the journal Pediatrics through early online release in their eFirst pages today and will appear in the journal's April issue. The study revealed that chromosomal microarray analysis (CMA) had the highest detection rate among clinically available genetic tests for patients with autism spectrum disorders and should be part of the initial diagnostic evaluation of all patients with ASDs unless a genetic diagnosis has already been made.

The study, a collaboration between the Autism Consortium and Children's Hospital Boston, led by Consortium members Bai-Lin Wu, David Miller, Kira Dies, and Yiping Shen, examined 933 families (children and parents) who received clinical genetic testing for a diagnosis of Autism Spectrum Disorder (ASD) between January 2006 and December 2008. The researchers compared the findings from three clinical genetic tests: G-banded karyotype and fragile X testing, the current standard battery of genetic testing, and chromosomal microarray analysis, for which testing guidelines have not yet been established. Chromosomal microarray analysis is similar to a karyotype, but can find much smaller chromosomal deletions and duplications.

The results showed that chromosomal microarray analysis identified more genetic abnormalities associated with autism than the standard testing methods combined:

  • Standard testing method G-banded karyotype testing yielded abnormal results in 19/852 patients (2.23%)
  • Standard testing method Fragile X testing results were abnormal in 4/861 patients (0.46%)
  • In contrast, chromosomal microarray analysis (CMA) identified deletions or d
    '/>"/>

Contact: Kathryn Morris
kathryn@proncall.com
845-635-9828
Autism Consortium
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. The Elizabeth Birt Center for Autism Law and Advocacy (EBCALA) Objects to Media Reports Tainting Autism Doctors and Misrepresenting Autism Treatments
2. Crossroads for Growth Drawing Attention This World Autism Day to Help NJ Families Obtain Autism Treatment
3. A possible early glimpse of autisms impact on older siblings
4. A mothers sensitivity may help language growth in children with autism spectrum disorder
5. Sumner Redstone Donates $1 Million to Autism Speaks to Support Autism Research and Programs
6. Court Orders Reinstatement of Vital, Cost-Saving Treatment for Children With Autism
7. True Signs of Autism May Not Appear Until 1st Birthday
8. Autisms earliest symptoms not evident in children under 6 months
9. Bonding Hormone Might Help Some With Autism
10. Another Study Refutes Vaccination-Autism Link
11. Autism Science Foundation Offers IMFAR Grants to Autism Stakeholders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/14/2014)... dense, urban centers around the world, many people live ... tall buildings that block sunlight. And as the global ... together, the darkness will only spread. , To ... translucent panel that redirects sunlight onto narrow streets and ... over the edge at an angle, where it spreads ...
(Date:4/14/2014)... professor of chemical engineering at Virginia Tech , ... analyze living cells. The long-term goal is to gain ... In his lab , Lu and his students ... events inside cells. These devices promote high sensitivity and ... cells. , Based on their record of achievements, the ...
(Date:4/14/2014)... discovery company Proteomics International has completed an important ... (CDx) test with the validation of several of ... the panel of biomarkers after taking 508 highly ... validated at high stringency using the company,s proprietary ... was then cross-validated using immunoassays in collaboration with ...
(Date:4/14/2014)... for high-risk bladder cancer, chemotherapy before or after ... practice. The findings are published early online in ... American Cancer Society. , Clinical trials have shown ... bladder cancer who are given chemotherapy before surgery. ... surgery also improves survival. To investigate the use ...
(Date:4/11/2014)... brain cell production could pave the way for treatments ... have gained new understanding of the role played by ... and brain cells are formed a process that ... Their findings could help explain what happens when cell ... characteristic of many diseases including cancer. , Researchers ...
Breaking Medicine News(10 mins):Health News:Let the sun shine in: Redirecting sunlight to urban alleyways 2Health News:Efficient analysis of small quantity of cells improves chances to understand disease 2
... plastic blood, which they claim could act as a substitute, ... in war zones. ,The new artificial blood is ... at their core, like haemoglobin, that can carry oxygen through ... for extra funding to develop a final prototype that would ...
... mumps beginning in Nova Scotia and now spreading in Ontario. ... affected. ,The latest outbreak of five people in ... has put health officials in top alert. ,Public-health ... booster shot, as the latest attacks prove that those vaccinated ...
... the University of Illinois at Chicago explain in the May ... the heart's pacemaker to slow the rapid beating of ... cell in the upper right chamber is responsible for setting ... to beat. In the human heart, one cell - the ...
... who had been crusading for the right to use marijuana ... federal government. ,"I've lost all faith in ... their constitutional right to life in this country," she said ... few months, and I wasn't happy about having to give ...
... A legal cocaine? That is what US-based Redux Beverages said it would ... drug, but merely an energy drink. ,In September ... a "legal alternative" to the illegal drug. ,Jamey Kirby, ... came to him during a brainstorming session at 1 o'clock in the ...
... the consequent quarantine of a woman has cost the Westchester ... up $75,000 dollars now. ,Based on the ... manager who had worked with high-risk obstetrics patients, isolated at ... February, said Deputy County Attorney Lori Alesio and Ryan's lawyer, ...
Cached Medicine News:Health News:Mumps Breaks Out In Canada 2Health News:Slowing the Racing Heart 2Health News:Medical Marijuana Activist Drops Lawsuit 2Health News:'Cocaine' Turns 'Censored' and Remains 'energy Drink' 2Health News:'Cocaine' Turns 'Censored' and Remains 'energy Drink' 3Health News:US County to Compensate Woman Wrongly Quarantined for TB 2
(Date:1/15/2014)... Jan. 15, 2014 AARP Foundation today announced ... support older adults suffering from the severe cold weather ... its members are committed to helping those in need; ... AARP Foundation will match dollar-for-dollar contributions up to $250,000, ... matching program will be administered through AARP Foundation. ...
(Date:1/15/2014)... -- Shire plc (LSE: SHP, NASDAQ: ... Fair Trading (OFT) approval condition to the announced tender offer ... VPHM).   As a result of the waiver, ... Shire expects to complete the tender offer on January 24, ... satisfaction of all of the remaining conditions to the tender ...
(Date:1/15/2014)... PALM BEACH GARDENS, Fla. , Jan. 15, 2014 /PRNewswire/ ... such as MRSA, C. difficile and TB in ambulances and ... manufactured by MRSA-UV is now being used by rescue personnel ... prevent EMS paramedics and transport patients from coming in contact ... Fire Rescue is the first in the nation to ...
Breaking Medicine Technology:AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 2AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 3Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3Superbugs No Longer Ride In Rescue Vehicles 2
... Sun Med TruFlow™ Oxygen flowmeter with a ... warranty covering calibration and manufacturing defects. A ... meet most needs. Also available with all ... power take-off and double unit configurations. Our ...
... series of time-tested Timeter® Classic Flowmeters demonstrates ... care providers and patients alike. You can ... see it in the craftsmanship. You can ... year. Every Timeter® Classic Flowmeter is hand-crafted ...
The Soft-Touch Timeter® Flowmeter is durable, long-lasting and easy to maintain. Timeter ® by Allied Flowmeters: Quality Plus Value....
The Soft-Touch Timeter® Flowmeter is durable, long-lasting and easy to maintain. Timeter ® by Allied Flowmeters: Quality Plus Value....
Medicine Products: