Navigation Links
Autism Consortium study in Pediatrics shows CMA finds more genetic abnormalities than current tests
Date:3/14/2010

Boston March 15, 2010 The Autism Consortium, an innovative research, clinical and family collaboration dedicated to catalyzing research and enhancing clinical care for families with autism spectrum disorders (ASDs), announced today that the results of its comparison study of genetic testing methods for autism spectrum disorders is available from the journal Pediatrics through early online release in their eFirst pages today and will appear in the journal's April issue. The study revealed that chromosomal microarray analysis (CMA) had the highest detection rate among clinically available genetic tests for patients with autism spectrum disorders and should be part of the initial diagnostic evaluation of all patients with ASDs unless a genetic diagnosis has already been made.

The study, a collaboration between the Autism Consortium and Children's Hospital Boston, led by Consortium members Bai-Lin Wu, David Miller, Kira Dies, and Yiping Shen, examined 933 families (children and parents) who received clinical genetic testing for a diagnosis of Autism Spectrum Disorder (ASD) between January 2006 and December 2008. The researchers compared the findings from three clinical genetic tests: G-banded karyotype and fragile X testing, the current standard battery of genetic testing, and chromosomal microarray analysis, for which testing guidelines have not yet been established. Chromosomal microarray analysis is similar to a karyotype, but can find much smaller chromosomal deletions and duplications.

The results showed that chromosomal microarray analysis identified more genetic abnormalities associated with autism than the standard testing methods combined:

  • Standard testing method G-banded karyotype testing yielded abnormal results in 19/852 patients (2.23%)
  • Standard testing method Fragile X testing results were abnormal in 4/861 patients (0.46%)
  • In contrast, chromosomal microarray analysis (CMA) identified deletions or d
    '/>"/>

Contact: Kathryn Morris
kathryn@proncall.com
845-635-9828
Autism Consortium
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. The Elizabeth Birt Center for Autism Law and Advocacy (EBCALA) Objects to Media Reports Tainting Autism Doctors and Misrepresenting Autism Treatments
2. Crossroads for Growth Drawing Attention This World Autism Day to Help NJ Families Obtain Autism Treatment
3. A possible early glimpse of autisms impact on older siblings
4. A mothers sensitivity may help language growth in children with autism spectrum disorder
5. Sumner Redstone Donates $1 Million to Autism Speaks to Support Autism Research and Programs
6. Court Orders Reinstatement of Vital, Cost-Saving Treatment for Children With Autism
7. True Signs of Autism May Not Appear Until 1st Birthday
8. Autisms earliest symptoms not evident in children under 6 months
9. Bonding Hormone Might Help Some With Autism
10. Another Study Refutes Vaccination-Autism Link
11. Autism Science Foundation Offers IMFAR Grants to Autism Stakeholders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... A surprising new study pulls back the curtain on ... differences in payment and income between physicians who perform ... , Contrary to perception, the research indicates, the physician ... and other procedure-performing doctors. , The new findings counter ... pay per minute explains why doctors who perform procedures ...
(Date:9/22/2014)... Mozes HealthDay Reporter MONDAY, ... American parents are aware of online physician-rating sites, and more ... their children, according to a new national study. The ... -- further suggest that negative online ratings may dissuade parents ... recommended by a neighbor. Conversely, a positive online rating ...
(Date:9/22/2014)... South Asians living in Canada have a higher rate ... compared with while people, McMaster researchers have found. ... Canadian Medical Association Journal (CMAJ Open) and may ... the fastest-growing ethnic groups in the country is the ... Canada, comprising about three percent of the population. They ...
(Date:9/22/2014)... researchers have published a pilot study showing the ... people with multiple sclerosis (MS). Improvements were ... and pain. "Development and effectiveness of a ... Description and outcomes" was epublished ahead of print ... of MS Care (doi: 10.7224/1537-2073.2013-045). The authors ...
(Date:9/22/2014)... Two new prescription devices approved by the U.S. Food ... people with migraine headaches who don,t tolerate migraine medications ... -- the Cefaly -- is designed to prevent migraines, ... meant to be used when migraines first start, according ... looking for alternative migraine treatments. Because these devices aren,t ...
Breaking Medicine News(10 mins):Health News:Think the system for paying US doctors is rigged to favor surgeons? Study may surprise you 2Health News:Think the system for paying US doctors is rigged to favor surgeons? Study may surprise you 3Health News:Think the system for paying US doctors is rigged to favor surgeons? Study may surprise you 4Health News:Many Parents Use Online Ratings to Pick a Pediatrician, Study Finds 2Health News:Many Parents Use Online Ratings to Pick a Pediatrician, Study Finds 3Health News:Higher risk of heart disease for South Asians in Canada 2Health News:Noninvasive Devices May Help Migraines, FDA Says 2
... from several misconceptions that people had about aging. A popular ... the happiest days of people's lives occur when they're young ... ,While old age was equated with unhappiness for other people, ... their old age. In other words older people seem to ...
... it is evident that a man is very critical and is ... and is admitted// in a Shenzhen hospital. It is very evident ... SAR's Centre for Health Protection said that the victim lives in ... a Hong Konger residing in Shenzhen. He fell ill after he ...
... and figures seemingly indicate that the number of violent ... over the past year//. According to the figures that ... shows that the staff had reported 224 incidents of ... ,Unison an organization that represents the health workers, says ...
... Cancer researchers in UK exclaimed children now become fond of ... meat// and fish – after surveying about 200 pairs of ... strong in high-protein dishes such as beef, lamb, fish, bacon ... to taste vegetables and dessert more preferably. ,Mothers ...
... According to the study it was found that Implantable ... //. But they are very efficient in reducing the ... published in the American Heart Association rapid access journal ... were sicker and more prone to develop heart failure,’ ...
... seizures, or psychogenic seizures are often misdiagnosed as epileptic ... epilepsy is caused by the abnormal electrical activity in ... are similar to epileptic seizures, they can be difficult ... 13, 2006, issue of Neurology, the scientific journal of ...
Cached Medicine News:Health News:Attitudes About Aging Different from Reality 2Health News:Attitudes About Aging Different from Reality 3Health News:Violence Against NHS Staff On The Raise 2Health News:Defibrillators Can Only Put off Heart Failure but Cannot Prevent One 2Health News:Clues To Identify Psychological Seizures 2Health News:Clues To Identify Psychological Seizures 3
(Date:9/22/2014)... Ill. , Sept. 22, 2014  AbbVie ... from several clinical studies evaluating potential new medicines ... at the upcoming 2014 European Society of Medical ... Madrid, Spain . Data being presented ... the safety and efficacy of veliparib (ABT-888), a ...
(Date:9/22/2014)... DIEGO , Sept. 22, 2014 Arena Pharmaceuticals, ... company is scheduled to present a corporate overview and ... on Friday, September 26, 2014, at 11:30 a.m. Eastern ... Hotel in New York City . ... will be available under the investor relations section of ...
(Date:9/22/2014)... According to the new ... (Equipment, Media and Reagents), by Source, by type, ... Toxicity Testing, Research, Drug Discovery) - Analysis & ... and studies the major market drivers, threats, opportunities, ... data tables and 64 figures spread through 225 ...
Breaking Medicine Technology:AbbVie to Present Clinical Study Data on Potential New Oncology Medicines at the 2014 European Society of Medical Oncology Annual Meeting 2AbbVie to Present Clinical Study Data on Potential New Oncology Medicines at the 2014 European Society of Medical Oncology Annual Meeting 3AbbVie to Present Clinical Study Data on Potential New Oncology Medicines at the 2014 European Society of Medical Oncology Annual Meeting 4Arena Pharmaceuticals to Present at the NewsMakers in the Biotech Industry Conference 2Arena Pharmaceuticals to Present at the NewsMakers in the Biotech Industry Conference 3Cell Line Development Market Worth $3.96 Billion by 2019 2Cell Line Development Market Worth $3.96 Billion by 2019 3Cell Line Development Market Worth $3.96 Billion by 2019 4
... Safety Knife with BD Xstar Blade includes ... protects the blade in prodedure and handling. ... on a grind-less process for manufacturing surgical ... sharpness and consistency. The arch style, ...
... Knife with BD Xstar Blade includes a ... the blade in prodedure and handling. ... a grind-less process for manufacturing surgical blades. ... and consistency. The arch style, single-bevel ...
... The BD Safety Knife with BD ... retractable shield that protects the blade in ... technology is based on a grind-less process ... process yields outstanding sharpness and consistency. ...
Bio-Rad's Genetic Systems HIV-1/HIV-2 PLUS O EIA is a unique assay that detects the broadest range of HIV....
Medicine Products: