Navigation Links
Australian team reveals world-first discovery in a 'floppy baby' syndrome
Date:5/25/2009

In a world first, West Australian scientists have cured mice of a devastating muscle disease that causes a Floppy Baby Syndrome a breakthrough that could ultimately help thousands of families across the globe.

The research, published online today in the Journal of Cell Biology, reveals how a team at the Western Australian Institute for Medical Research (WAIMR) has restored muscle function in mice with one type of Floppy Baby Syndrome a congenital myopathy disorder that causes babies to be born without the ability to properly use their muscles.

The currently incurable genetic diseases render most of the affected children severely paralysed and take the lives of the majority of these children before the age of one.

Dr Kristen Nowak, lead author on the publication, said the team was extremely encouraged that it had been able to cure a group of mice born with the condition.

"The mice with Floppy Baby Syndrome were only expected to live for about nine days, but we managed to cure them so they were born with normal muscle function, allowing them to live naturally and very actively into old age," she said.

"This is an important step towards one day hopefully being able to better the lives of human patients mice who were cured of the disease lived more than two years, which is very old age for a mouse."

Dr Nowak said the team was able to cure the mice with the recessive form of the genetic condition by replacing missing skeletal muscle actin a protein integral in allowing muscles to contract with similar actin found in the heart.

"Earlier in our search to tackle these diseases, we discovered a number of children who, despite having no skeletal muscle actin in their skeletal muscle due to their genetic mutation, were not totally paralysed at birth," she said.

"On closer inspection, we found it was because heart actin another form of the protein was abnormally "switched on" in their s
'/>"/>

Contact: Natalie Papadopoulos
natalie@capturemedia.com.au
61-040-798-4435
Research Australia
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Australian clinical trials threatened: Jobs and patient access to new treatments at stake
2. MTF, Largest Tissue Bank, Provides Skin for Victims of Australian Wildfires
3. Cephalon Launches Takeover Offer for Australian Biotechnology Company, Arana Therapeutics
4. Frost & Sullivan: Australian Pharmaceuticals and Life Sciences IT Market Is Still Growing
5. ATS Medical Announces Australian Regulatory Approval for ATS 3f Aortic Bioprosthesis
6. Australian technology in global health toolkit
7. Mottram Honours His End of the HBA Great Australian Run challenge
8. HBA People Walk the Talk for Better Health in the HBA Great Australian Run
9. Indigenous Australian patients confused and frustrated by kidney disease
10. New Cosmetic Trends Change the Face of the Australian Botox Market
11. Australian over-50s walk away memory problems in world-first trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2015)... 2015 Henry Mayo Newhall Hospital, located ... Exchange to automatically send continuation of care documents ... further improve communication with clinics and other ambulatory practices, ... solution. , “Provider Alert will enable the ... information they need to provide continuing care in real ...
(Date:4/21/2015)... “ ZeroWire ” was featured on NewsWatch ... a look at the latest and coolest technology products ... reporter for NewsWatch and a technology expert, conducted the ... security system and lifestyle management hub. , According to ... million burglaries in 2010. It goes without saying that ...
(Date:4/21/2015)... Angelo’s FabriClean has recently announced that the company ... avail the area rug cleaning services. Area rug cleaning ... equipments, making use of the quick drying technique to ... pressure steam extraction to clean even the most stubborn ... made with delicate fabric. , “Good maintenance and ...
(Date:4/21/2015)... Lowcostcarinsuranceprice.com has released a new blog post explaining how ... , SUVs are large vehicles that fare well in ... a smaller regular car shows that passengers from the first ... safer in crashes, but these large vehicles may be unstable ... It is now possible to find low cost car insurance ...
(Date:4/21/2015)... California (PRWEB) April 21, 2015 On ... Movie Awards” EcoLuxe Lounge at the world famous Avalon ... of sustainable product placement in TV and film, the ... makes appearances at many awards ceremonies and festivals throughout ... top providers of eco-friendly and socially conscious products and ...
Breaking Medicine News(10 mins):Health News:Henry Mayo Newhall Hospital to Improve Ambulatory Information Sharing with Summit Healthcare's Summit Provider Alert 2Health News:A Leader in Home Security was Featured on NewsWatch Television 2Health News:Angelo’s FabriClean Now Offers Area Rug Cleaning in South Surrey with Complimentary Pick-Up and Delivery 2Health News:Auto Insurance Quotes For SUVs Are Available Online 2Health News:Hollywood's Santana Dempsey and Choices Recovery South Bend Examine Victory over Personal Struggles 2
... network of collaborative research. Building on a tool that was ... of Brain , Dr. Yaniv Assaf of Tel Aviv ... of scientists to understand how different parts of the human ... "brain atlas." Brain researchers already know that autism and ...
... as young as four weeks old are being fed a ... new Australian research. A study published in the journal ... been introduced to high fat, salt and sugar foods, despite ... Researcher Jane Scott and colleagues tracked 587 women ...
... Gardner HealthDay Reporter , MONDAY, Sept. 6 ... and proteins from vegetable sources rather than meats is ... types of diets over two decades, researchers found that ... death from cardiovascular disease and cancer, and a lower ...
... About 17 percent of all visits to hospital emergency ... retail medical clinics or urgent care centers, potentially saving ... a new RAND Corporation study. Conditions that could ... fractures and lacerations, according to findings published in the ...
... of California, San Diego School of Medicine have shown ... examining dynamic geometric patterns than they do looking at ... either typical or developmentally delayed toddlers. The results ... patterns early in life may be a signature behavior ...
... a combination of medication and a psychosocial intervention appear ... improved insight, quality of life and social functioningthan those ... September issue of Archives of General Psychiatry , ... the mainstay of therapy for patients with schizophrenia, but ...
Cached Medicine News:Health News:Mapping a brain atlas 2Health News:What are babies made of? Research shows for some it is sugar, salt and not all things nice 2Health News:Low-Carb Diets Heavy on Meat May Raise Health Risks 2Health News:Many hospital emergency department visits could be treated elsewhere, study finds 2Health News:Many hospital emergency department visits could be treated elsewhere, study finds 3Health News:Visual pattern preference may be indicator of autism in toddlers 2Health News:Visual pattern preference may be indicator of autism in toddlers 3Health News:Combining medication and psychosocial treatments may benefit patients with early-stage schizophrenia 2
(Date:4/21/2015)... 21, 2015 The Natural Products Association ... supplement and natural products industry. NPA Senior Vice ... Hilmas , M.D., Ph.D., former Chief of the ... of Dietary Supplement Programs at the Food and ... to link dietary supplement intake with an increased ...
(Date:4/21/2015)... , Apr. 21, 2015 Algae International Group, ... Seed & Oil Company, today announced exceptional Hempster T-Shirt ... American Seed & Oil Company has introduced four t-shirt ... hundred percent of the profit from the online sales ... the next year will be donated to the  Marijuana ...
(Date:4/21/2015)... April 21, 2015 InfuSystem Holdings, Inc. (NYSE ... and related services for the healthcare industry in ... Canada , announces today that it has closed ... the assets of Ciscura Holding Company, Inc., and its ... , was a privately-held Southeastern regional provider of ambulatory ...
Breaking Medicine Technology:NPA Chief Scientist Comments on Research Associating Dietary Supplements with Increased Cancer Risk 2NPA Chief Scientist Comments on Research Associating Dietary Supplements with Increased Cancer Risk 3American Seed & Oil Company 420 Hempster T-Shirt Sales Soar; Online Sales Launched Yesterday with Start of 420 Week; Over 2000 Shirts Sold So Far 2InfuSystem Announces Acquisition Of Ciscura's Infusion Pump Fleet 2InfuSystem Announces Acquisition Of Ciscura's Infusion Pump Fleet 3InfuSystem Announces Acquisition Of Ciscura's Infusion Pump Fleet 4
... 11, 2007 - Repros,Therapeutics Inc. (NasdaqGM:RPRX) today released ... in the treatment of,endometriosis. This study, conducted in ... months of dosing. The,study included three dose levels ... The positive control was Lucrin(R), a GnRH,agonist also ...
... Conn.--(BUSINESS WIRE)--Jun 11, 2007 - Neurogen,Corporation (Nasdaq: NRGN) ... studies for NG2-73, the Company's lead compound,for the ... SLEEP,2007 Annual Meeting of the Associated Professional Sleep ... studies,with NG2-73 in chronic insomnia patients are currently ...
Cached Medicine Technology:Repros Reports That Proellex Has Demonstrated Superior Efficacy and,Safety in Endometriosis When Compared to Standard of Drug Care 2Repros Reports That Proellex Has Demonstrated Superior Efficacy and,Safety in Endometriosis When Compared to Standard of Drug Care 3Repros Reports That Proellex Has Demonstrated Superior Efficacy and,Safety in Endometriosis When Compared to Standard of Drug Care 4Repros Reports That Proellex Has Demonstrated Superior Efficacy and,Safety in Endometriosis When Compared to Standard of Drug Care 5Repros Reports That Proellex Has Demonstrated Superior Efficacy and,Safety in Endometriosis When Compared to Standard of Drug Care 6Neurogen Proprietary Insomnia Compound Data Presented at Associated,Professional Sleep Societies Annual Meeting 2Neurogen Proprietary Insomnia Compound Data Presented at Associated,Professional Sleep Societies Annual Meeting 3Neurogen Proprietary Insomnia Compound Data Presented at Associated,Professional Sleep Societies Annual Meeting 4