Navigation Links
Australian team reveals world-first discovery in a 'floppy baby' syndrome
Date:5/25/2009

In a world first, West Australian scientists have cured mice of a devastating muscle disease that causes a Floppy Baby Syndrome a breakthrough that could ultimately help thousands of families across the globe.

The research, published online today in the Journal of Cell Biology, reveals how a team at the Western Australian Institute for Medical Research (WAIMR) has restored muscle function in mice with one type of Floppy Baby Syndrome a congenital myopathy disorder that causes babies to be born without the ability to properly use their muscles.

The currently incurable genetic diseases render most of the affected children severely paralysed and take the lives of the majority of these children before the age of one.

Dr Kristen Nowak, lead author on the publication, said the team was extremely encouraged that it had been able to cure a group of mice born with the condition.

"The mice with Floppy Baby Syndrome were only expected to live for about nine days, but we managed to cure them so they were born with normal muscle function, allowing them to live naturally and very actively into old age," she said.

"This is an important step towards one day hopefully being able to better the lives of human patients mice who were cured of the disease lived more than two years, which is very old age for a mouse."

Dr Nowak said the team was able to cure the mice with the recessive form of the genetic condition by replacing missing skeletal muscle actin a protein integral in allowing muscles to contract with similar actin found in the heart.

"Earlier in our search to tackle these diseases, we discovered a number of children who, despite having no skeletal muscle actin in their skeletal muscle due to their genetic mutation, were not totally paralysed at birth," she said.

"On closer inspection, we found it was because heart actin another form of the protein was abnormally "switched on" in their s
'/>"/>

Contact: Natalie Papadopoulos
natalie@capturemedia.com.au
61-040-798-4435
Research Australia
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Australian clinical trials threatened: Jobs and patient access to new treatments at stake
2. MTF, Largest Tissue Bank, Provides Skin for Victims of Australian Wildfires
3. Cephalon Launches Takeover Offer for Australian Biotechnology Company, Arana Therapeutics
4. Frost & Sullivan: Australian Pharmaceuticals and Life Sciences IT Market Is Still Growing
5. ATS Medical Announces Australian Regulatory Approval for ATS 3f Aortic Bioprosthesis
6. Australian technology in global health toolkit
7. Mottram Honours His End of the HBA Great Australian Run challenge
8. HBA People Walk the Talk for Better Health in the HBA Great Australian Run
9. Indigenous Australian patients confused and frustrated by kidney disease
10. New Cosmetic Trends Change the Face of the Australian Botox Market
11. Australian over-50s walk away memory problems in world-first trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... and sound may be bad for your waistline. TV ... watching an excerpt from a Hollywood action film than ... been blamed for helping Americans to gain weight because ... why has been on the medium and not the ... cause people to eat more, including reading, listening to ...
(Date:9/1/2014)... (HealthDay News) -- You may be able to convince your ... research suggests. The study included eight overweight and obese ... meant to change how people react to different foods. These ... and obese people who weren,t in the program. Both ... study and again six months later. The scans revealed that ...
(Date:9/1/2014)... New York (PRWEB) September 01, 2014 ... room in a hospital for performing surgical operations. An ... as operating tables, surgical booms, operating room lights, imaging ... According to a report by Transparency Market Research, a ... is expected to reach USD 4.5 billion by 2019. ...
(Date:9/1/2014)... HealthDay Reporter FRIDAY, Aug. ... given to two American aid workers successfully cured a group ... researchers report. The drug, ZMapp, prompted recovery in all ... the medication until five days after infection. ZMapp even ... or even hours away from death, said study senior author ...
(Date:9/1/2014)... 01, 2014 The National Association of ... that Dawn Bazarko, DNP, MPH, RN, and Adriana Perez, ... American Academy of Nursing. They will be inducted with ... FACHE, whose induction we reported last May. , Our ... during the 2014 American Academy of Nursing Policy Conference ...
Breaking Medicine News(10 mins):Health News:Research letter: Viewers ate more while watching Hollywood action flick on TV 2Health News:Train Your Brain to Choose Fruit Salad Over French Fries 2Health News:Operating Room Equipment Market Study 2019 by Transparency Market Research 2Health News:Operating Room Equipment Market Study 2019 by Transparency Market Research 3Health News:Monkey Trial Supports Ebola Drug That May Have Helped 2 Stricken Americans 2Health News:Monkey Trial Supports Ebola Drug That May Have Helped 2 Stricken Americans 3Health News:Two Additional NAHN Members to be Inducted as Fellows of the American Academy of Nursing 2Health News:Two Additional NAHN Members to be Inducted as Fellows of the American Academy of Nursing 3Health News:Two Additional NAHN Members to be Inducted as Fellows of the American Academy of Nursing 4
... might be associated with a one third reduction in ... published on bmj.com today. The findings confirm ... potential beneficial link between chocolate consumption and heart health. ... to test whether chocolate actually causes this reduction or ...
... San Francisco, CA The 2011 Annual Meeting & OTO ... Neck Surgery Foundation (AAO-HNSF), the largest meeting of ear, nose, ... 2011, in San Francisco, CA. Featuring more than 386 ... hours for attendees, the annual meeting is a unique opportunity ...
... blood vessels is mostly done the same way today ... the French surgeon Alexis Carrel won a Nobel Prize for ... Stanford University School of Medicine has developed a sutureless method ... In animal studies, a team led by Stanford microsurgeon ...
... The death rate among patients prescribed a statin in a ... those given a placebo, even though most participants in both ... Cardiac Outcomes Trial, was stopped early because the statin was ... new analysis has shown that eight years on, the most ...
... pacing on implantable cardioverter-defibrillator (ICD) patient survival is ... mitigated by cardiac resynchronization therapy (CRT), based on ... society of Cardiology (ESC) Congress Aug 28 in ... the average patient, despite having severe left ventricular ...
... 27 (HealthDay News) -- As another school year begins, ... books and other supplies can lead to back injury. ... to time. They often carry much more than they ... unnecessary items," Dr. Joshua Hyman, director of orthopedic surgery ...
Cached Medicine News:Health News:It's official -- chocolate linked to heart health 2Health News:2011 AAO-HNSF poster presentations 2Health News:2011 AAO-HNSF poster presentations 3Health News:2011 AAO-HNSF poster presentations 4Health News:2011 AAO-HNSF poster presentations 5Health News:2011 AAO-HNSF poster presentations 6Health News:2011 AAO-HNSF poster presentations 7Health News:2011 AAO-HNSF poster presentations 8Health News:2011 AAO-HNSF poster presentations 9Health News:2011 AAO-HNSF poster presentations 10Health News:2011 AAO-HNSF poster presentations 11Health News:2011 AAO-HNSF poster presentations 12Health News:2011 AAO-HNSF poster presentations 13Health News:2011 AAO-HNSF poster presentations 14Health News:2011 AAO-HNSF poster presentations 15Health News:2011 AAO-HNSF poster presentations 16Health News:2011 AAO-HNSF poster presentations 17Health News:2011 AAO-HNSF poster presentations 18Health News:2011 AAO-HNSF poster presentations 19Health News:2011 AAO-HNSF poster presentations 20Health News:2011 AAO-HNSF poster presentations 21Health News:Stanford researchers invent sutureless method for joining blood vessels 2Health News:Stanford researchers invent sutureless method for joining blood vessels 3Health News:Stanford researchers invent sutureless method for joining blood vessels 4Health News:Statins reduce deaths from infection and respiratory illness, 8 years on from trial 2Health News:Patients are living longer with ICDs, but pacing impacts survival rates 2
(Date:8/29/2014)... Aug. 29, 2014   Vittamed Corporation , a neurodiagnostics ... announced today that T. (Teo) Forcht Dagi , MD, ... Board of Directors. " Teo Forcht Dagi ... neurosurgery, medical innovation and venture capital," said Remis Bistras ... to add his clinical, strategic, and entrepreneurial expertise to our ...
(Date:8/29/2014)... /PRNewswire-iReach/ -- ChemImage will present a workshop focused on ... Forensic Science Society,s 22 nd International Symposium ... Australia .  Forensic Scientists will be in ... imaging can bring to examination procedures. ... Product Development at ChemImage, will host a workshop ...
(Date:8/29/2014)... Calif. , Aug. 29, 2014  Pacific Medical ... its new website design . The main website, ... that showcases the company,s new services and content relevant ... implementing a new streamlined design, viewers can now better ... for health care practices and create a more visible ...
Breaking Medicine Technology:Vittamed Adds Prominent Neurosurgeon and Venture Capitalist T. Forcht Dagi to Board of Directors 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 3PMDS Announces New Website 2
... Nov. 20 Medco Health Solutions, Inc (NYSE: ... healthcare through an advanced, wired pharmacy paradigm that is already ... curve downward -- making medicine smarter for the benefit of ... the elements in its strategy enable "Smarter Medicine" to help ...
... , NEW YORK, ... a new market research report is available in ... Analysis and Forecasts to 2015 , ... , India Medical Equipment Market Analysis and Forecasts ...
Cached Medicine Technology:Medco Reforming Healthcare with 'Smarter Medicine'; Wired, Transformational Pharmacy Model Advances Clinical Quality and Lowers Cost 2Medco Reforming Healthcare with 'Smarter Medicine'; Wired, Transformational Pharmacy Model Advances Clinical Quality and Lowers Cost 3Medco Reforming Healthcare with 'Smarter Medicine'; Wired, Transformational Pharmacy Model Advances Clinical Quality and Lowers Cost 4Medco Reforming Healthcare with 'Smarter Medicine'; Wired, Transformational Pharmacy Model Advances Clinical Quality and Lowers Cost 5Reportlinker Adds India Medical Equipment Market Analysis and Forecasts to 2015 2Reportlinker Adds India Medical Equipment Market Analysis and Forecasts to 2015 3Reportlinker Adds India Medical Equipment Market Analysis and Forecasts to 2015 4Reportlinker Adds India Medical Equipment Market Analysis and Forecasts to 2015 5Reportlinker Adds India Medical Equipment Market Analysis and Forecasts to 2015 6Reportlinker Adds India Medical Equipment Market Analysis and Forecasts to 2015 7Reportlinker Adds India Medical Equipment Market Analysis and Forecasts to 2015 8Reportlinker Adds India Medical Equipment Market Analysis and Forecasts to 2015 9Reportlinker Adds India Medical Equipment Market Analysis and Forecasts to 2015 10Reportlinker Adds India Medical Equipment Market Analysis and Forecasts to 2015 11Reportlinker Adds India Medical Equipment Market Analysis and Forecasts to 2015 12Reportlinker Adds India Medical Equipment Market Analysis and Forecasts to 2015 13
Infant Nebulizer Kit W/Misty-Nebulizer 30/CS CE Mark Only...
... Suggested Clinical Applications:, ,Cool Aerosol Therapy. ... open system devices such as aerosol masks, ... that provide only limited FIO2 and limited ... Nebulizer guards against accidental dilution with room ...
... new PARI TREK™ Compact Compressor is for ... aerosol treatments anywhere and everywhere. The compressor ... versatile power source optionsworldwide AC compatibility (100 ... battery, permit patients the freedom to take ...
... ,Allied Healthcares Timeter® PCS 414 portable air ... compressors that you may wonder if its running. ... features a durable, mar-resistant steel case thats easy ... only 26.5 pounds. The PCS 414 has been ...
Medicine Products: