Navigation Links
Australian Study Seeks Genetic Roots of Cerebral Palsy
Date:7/21/2008

Reseachers to gather 10,000 samples in study of this pregnancy complication

MONDAY, July 21 (HealthDay News) -- Australian researchers are recruiting 10,000 people to participate in the world's largest study of the possible genetic causes of cerebral palsy.

The study will include 5,000 people from families with an affected child and 5,000 people from unaffected families. Researchers will collect genetic samples by taking cheek swabs from mothers and their children.

Cerebral palsy, which affects one in 500 children worldwide, is one of the most serious pregnancy/birth complications. People with cerebral palsy lack control of their movement and posture as a result of brain injury in the neuro-motor region. Symptoms range from poor muscle coordination to quadriplegia.

"Our study will investigate a key issue behind cerebral palsy: whether genetic factors make women more vulnerable to environmental risks that affect the brain of their unborn child. These risks -- such as prematurity and infections -- combined with genetic susceptibility mean that babies could be at double jeopardy of cerebral palsy," research leader Professor Alastair MacLennan, head of obstetrics and gynecology at the University of Adelaide, said in a university news release.

"Recent studies by our group suggest that cerebral palsy may be associated with genetic and other mutations that may increase blood clotting within the brain," MacLennan said. "An association between cerebral palsy and different types of herpes virus infection -- such as cold sores and chicken pox -- has also been discovered in South Australian studies. The next step is to see if this is true in a much large population, comparing the genetics of both mother and child."

It was once believed that low oxygen levels during birth caused cerebral palsy, but this is rarely the case, MacLennan said.

"Obstetric care and Caesarean deliveries have increased sixfold over the last 50 years, but the incidence of cerebral palsy cases has remained the same. Most of the cases are associated with problems during pregnancy and possible genetic susceptibility. Currently, there is no cure or way to prevent cerebral palsy," he noted.

If this study confirms that genetic mutations can lead to cerebral palsy, it may help lead to the development of gene therapy or drugs that can prevent the condition.

More information

The U.S. Centers for Disease Control and Prevention has more about cerebral palsy.



-- Robert Preidt



SOURCE: University of Adelaide, news release, July 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
2. Bioniche Responds to Australian Equine Influenza Outbreak
3. Thomson Scientific Ranks Australian Universities and Research Institutes
4. Video: BSP Pharma Inc. Announces Groundbreaking Findings from The Australian Centre for Complementary Medicine Education and Research Joint Health Clinical Study
5. Thomson Scientific To Honor Australias Top Researchers With Dedicated Australian Research Day
6. Cardiums InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems
7. Rising Australian biotech stars set to connect on the world stage
8. Older Australians at risk of sun-related skin cancer death
9. 2701 Australian: A Unique Partnership
10. $100 million supercomputing program boosts Australian medical research capacity
11. China Medicine Corporation Obtains Australian Patent for rADTZ
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the ... a national organization of elder law and special needs planning attorneys. “Membership in ElderCounsel ... also provides a forum to network with elder law attorneys nationwide,” said Somekh. ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term ... long-term care insurance companies have a waiver for care if the client has a ... when the family pays for care, is often waived, so the benefits from their ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network ... advocate for action towards gender equality at their inaugural Summit in New York City ... and reached a social audience of over 3 million. To watch the Mobilize Women ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... the most popular and least understood books in the Holy Scriptures, Revelation. The Book ... have baffled scholars for centuries. Many have tossed it off as mere rubbish, but ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a ... has been awarded a contract by the Center for Medicare and Medicaid Services ... accelerate the enterprise use of Agile methodologies in a consistent and high value ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... announces the European launch of their new low volume, high throughput ... Cambridge, U.K on October 4th. The new ... unprecedented speed and sensitivity while using far less sample volume through ... ... ...
(Date:9/28/2017)... Hill-Rom Holdings, Inc. (NYSE: HRC), will host its fiscal ... Friday, November 3, 2017, beginning at 7:00 a.m. (CDT) ... a.m. (CDT) / 9:30 a.m. (EDT). In ... guidance for 2018, Hill-Rom executives will also highlight the ... long-range financial outlook through 2020. ...
(Date:9/27/2017)... 2017  Commended for their devotion to personalized service, SMP ... number one in the South Florida Business Journal,s 50 Fastest-Growing ... yearly list, the national specialty pharmacy has found its niche.  ... will soon be honored by SFBJ as the 2017 Power ... Set to receive his award in October, Bardisa said of ...
Breaking Medicine Technology: