Navigation Links
Australian Study Seeks Genetic Roots of Cerebral Palsy
Date:7/21/2008

Reseachers to gather 10,000 samples in study of this pregnancy complication

MONDAY, July 21 (HealthDay News) -- Australian researchers are recruiting 10,000 people to participate in the world's largest study of the possible genetic causes of cerebral palsy.

The study will include 5,000 people from families with an affected child and 5,000 people from unaffected families. Researchers will collect genetic samples by taking cheek swabs from mothers and their children.

Cerebral palsy, which affects one in 500 children worldwide, is one of the most serious pregnancy/birth complications. People with cerebral palsy lack control of their movement and posture as a result of brain injury in the neuro-motor region. Symptoms range from poor muscle coordination to quadriplegia.

"Our study will investigate a key issue behind cerebral palsy: whether genetic factors make women more vulnerable to environmental risks that affect the brain of their unborn child. These risks -- such as prematurity and infections -- combined with genetic susceptibility mean that babies could be at double jeopardy of cerebral palsy," research leader Professor Alastair MacLennan, head of obstetrics and gynecology at the University of Adelaide, said in a university news release.

"Recent studies by our group suggest that cerebral palsy may be associated with genetic and other mutations that may increase blood clotting within the brain," MacLennan said. "An association between cerebral palsy and different types of herpes virus infection -- such as cold sores and chicken pox -- has also been discovered in South Australian studies. The next step is to see if this is true in a much large population, comparing the genetics of both mother and child."

It was once believed that low oxygen levels during birth caused cerebral palsy, but this is rarely the case, MacLennan said.

"Obstetric care and Caesarean deliveries have increased sixfold over the last 50 years, but the incidence of cerebral palsy cases has remained the same. Most of the cases are associated with problems during pregnancy and possible genetic susceptibility. Currently, there is no cure or way to prevent cerebral palsy," he noted.

If this study confirms that genetic mutations can lead to cerebral palsy, it may help lead to the development of gene therapy or drugs that can prevent the condition.

More information

The U.S. Centers for Disease Control and Prevention has more about cerebral palsy.



-- Robert Preidt



SOURCE: University of Adelaide, news release, July 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
2. Bioniche Responds to Australian Equine Influenza Outbreak
3. Thomson Scientific Ranks Australian Universities and Research Institutes
4. Video: BSP Pharma Inc. Announces Groundbreaking Findings from The Australian Centre for Complementary Medicine Education and Research Joint Health Clinical Study
5. Thomson Scientific To Honor Australias Top Researchers With Dedicated Australian Research Day
6. Cardiums InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems
7. Rising Australian biotech stars set to connect on the world stage
8. Older Australians at risk of sun-related skin cancer death
9. 2701 Australian: A Unique Partnership
10. $100 million supercomputing program boosts Australian medical research capacity
11. China Medicine Corporation Obtains Australian Patent for rADTZ
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2017)... ... , ... More than half of Americans suffering from noise-induced hearing loss do ... that causes hearing loss? May 1 marks the beginning of Better Hearing & Speech ... well as schedule a hearing evaluation for anyone with concerns about his/her hearing. , ...
(Date:4/28/2017)... , ... April 28, 2017 , ... ... (The National Campaign) announces its support for the Access to Contraception for Women ... Shaheen (D-NH) and Rep. Jackie Speier (D-CA), will help to ensure that all ...
(Date:4/28/2017)... ... April 28, 2017 , ... Somnoware, a leading provider of ... which enables sleep physicians to create and edit their interpretation reports. This solution ... a familiar interface that does not require additional training to use. It also ...
(Date:4/28/2017)... ... ... affects much more than energy – it also has mental and physical benefits. According to ... time, which can increase the risk of having a car accident. , This week ... to help you sleep better and feel better:, , Turn off ...
(Date:4/28/2017)... ... April 28, 2017 , ... Ushio America proudly introduces ... an instant energy-saving solution for F32T8 fluorescent lamps on most instant-start and programmed-start ... 50,000 hour rated lamps utilize the existing electronic ballast, saving labor and maintenance ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... , April 20, 2017 Research and ... Technologies - Innovation Driven by Rapidly Expanding Injectables Market and Increasing ... their offering. ... for drug delivery technologies will rise from USD 20 Billion in ... Global Drug Delivery Technologies - Innovation Driven by Rapidly Expanding ...
(Date:4/20/2017)... , April 20, 2017 Research ... Pharmacogenomics Market Size, Market Share, Application Analysis, Regional Outlook, Growth ... report to their offering. ... The global pharmacogenomics market was valued at US$ 7,167.6 ... Mn by 2024, expanding at a CAGR of 5.6% from ...
(Date:4/19/2017)... Medical Corporation (TSX: CRH) (NYSE MKT: CRHM) (the "Company"), announces that it ... 2017 at the Sheraton Hotel in Toronto, Ontario ... the Company is scheduled to present on Tuesday, May 2 at ... Chairman of the Board, Tony Holler will also attend ... For more details ...
Breaking Medicine Technology: