Navigation Links
Australian Study Seeks Genetic Roots of Cerebral Palsy
Date:7/21/2008

Reseachers to gather 10,000 samples in study of this pregnancy complication

MONDAY, July 21 (HealthDay News) -- Australian researchers are recruiting 10,000 people to participate in the world's largest study of the possible genetic causes of cerebral palsy.

The study will include 5,000 people from families with an affected child and 5,000 people from unaffected families. Researchers will collect genetic samples by taking cheek swabs from mothers and their children.

Cerebral palsy, which affects one in 500 children worldwide, is one of the most serious pregnancy/birth complications. People with cerebral palsy lack control of their movement and posture as a result of brain injury in the neuro-motor region. Symptoms range from poor muscle coordination to quadriplegia.

"Our study will investigate a key issue behind cerebral palsy: whether genetic factors make women more vulnerable to environmental risks that affect the brain of their unborn child. These risks -- such as prematurity and infections -- combined with genetic susceptibility mean that babies could be at double jeopardy of cerebral palsy," research leader Professor Alastair MacLennan, head of obstetrics and gynecology at the University of Adelaide, said in a university news release.

"Recent studies by our group suggest that cerebral palsy may be associated with genetic and other mutations that may increase blood clotting within the brain," MacLennan said. "An association between cerebral palsy and different types of herpes virus infection -- such as cold sores and chicken pox -- has also been discovered in South Australian studies. The next step is to see if this is true in a much large population, comparing the genetics of both mother and child."

It was once believed that low oxygen levels during birth caused cerebral palsy, but this is rarely the case, MacLennan said.

"Obstetric care and Caesarean deliveries have increased sixfold over the last 50 years, but the incidence of cerebral palsy cases has remained the same. Most of the cases are associated with problems during pregnancy and possible genetic susceptibility. Currently, there is no cure or way to prevent cerebral palsy," he noted.

If this study confirms that genetic mutations can lead to cerebral palsy, it may help lead to the development of gene therapy or drugs that can prevent the condition.

More information

The U.S. Centers for Disease Control and Prevention has more about cerebral palsy.



-- Robert Preidt



SOURCE: University of Adelaide, news release, July 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
2. Bioniche Responds to Australian Equine Influenza Outbreak
3. Thomson Scientific Ranks Australian Universities and Research Institutes
4. Video: BSP Pharma Inc. Announces Groundbreaking Findings from The Australian Centre for Complementary Medicine Education and Research Joint Health Clinical Study
5. Thomson Scientific To Honor Australias Top Researchers With Dedicated Australian Research Day
6. Cardiums InnerCool Therapies Unit Announces Australian Distribution Agreement for CoolBlue and Rapid Blue Systems
7. Rising Australian biotech stars set to connect on the world stage
8. Older Australians at risk of sun-related skin cancer death
9. 2701 Australian: A Unique Partnership
10. $100 million supercomputing program boosts Australian medical research capacity
11. China Medicine Corporation Obtains Australian Patent for rADTZ
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2016)... , ... May 04, 2016 , ... ... Dr. Todd Rider's research and development of DRACO broad-spectrum antiviral therapeutics. DRACOs have ... campaign that starts on May 3, 2016 at http://igg.me/at/EndTheVirus and runs ...
(Date:5/4/2016)... (PRWEB) , ... May 04, 2016 , ... ... and Continence Nurses (WOCN) Society™ and Canadian Association for Enterostomal Therapy (CAET) ... promotion, time saving and planning tools to attendees and exhibitors for the 2016 ...
(Date:5/4/2016)... ... May 04, 2016 , ... May kicked off with ... across the United States. Dermatologist Dr. Ellen Turner is encouraging her patients, as well ... and focus on skin safety and health now and in the future. , The ...
(Date:5/4/2016)... ... May 04, 2016 , ... Recognizing that lifestyle medicine is essential ... Verywell, have tapped David Katz, MD, MPH, president of the American College of ... to lifestyle medicine is especially gratifying,” said Katz. “There is so much opportunity to ...
(Date:5/4/2016)... ... May 04, 2016 , ... ... and compact tactical (6.7 inch) dual-light flashlights in models NSP-9842XL and NSR-9844XL ... (average retail starting at $59.95) uses 2 included CR-123 batteries to produce up ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... BROOMALL, Pa. , May 3, 2016 ... Attorney Jack Whelan and Delaware County ... NARCAN® (naloxone HCI) Nasal Spray in all ACME ... the U.S. Centers for Disease Control and Prevention (CDC), naloxone has ... 2014, when police officers in Delaware County ...
(Date:5/3/2016)... (NYSE: DPLO) announced today that it is celebrating Hepatitis Awareness Month with a campaign to ... personal story and encourage those at risk to get tested and begin the road to ... ... ... (PRNewsFoto/Diplomat Pharmacy, Inc.) ...
(Date:5/3/2016)... , May 3, 2016 Intec ... a clinical-stage biopharmaceutical company, today announced the appointment of ... Regulatory Affairs. "Ms. Strauss-Levy has 15 years ... has established an outstanding track record, having supported the ... regulatory approval processes in the United States ...
Breaking Medicine Technology: