Navigation Links
Atkins-Like Diet Cuts Epileptic Seizures

High-fat, low-carb plan may work when other treatments fail, study says

THURSDAY, Jan. 31 (HealthDay News) -- Adults with epilepsy who have failed other treatments may be able to dramatically reduce their number of seizures by following a modified Atkins-like diet, Johns Hopkins researchers report.

The high-protein, low-carbohydrate diet has already been shown to be valuable in controlling seizures in children, and now results from a small study suggest that the diet also works for adults.

"There are a lot of adults with very bad seizures. There are a lot of adults who have failed medicines and are not candidates for other treatments," said lead researcher Dr. Eric H. Kossoff, an assistant professor of neurology and pediatrics at Johns Hopkins School of Medicine.

For the study, Kossoff's team gave the diet to 30 adults who had unsuccessfully tried at least two anti-convulsant drugs and had an average of 10 seizures a week. The eating plan restricts patients to 15 grams of carbohydrates a day. Most of the calories come from fats such as eggs, meats, oils and heavy cream. In addition, patients are free to eat as much protein and no-carb drinks as they want.

"There was good news and bad news," Kossoff said. "The good news was it worked. The bad news it was tough. About 30 percent of the patients stopped the diet. This happened even in patients who had good seizure control who thought the diet was still too tough to do."

After a month on the diet, half the patients reported suffering 50 percent fewer seizures. At three months, about one-third of the patients cut the frequency of seizures by half.

However, by three months, one-third of the patients had dropped out of the study because they found the diet too restrictive, Kossoff said.

The diet's side effects, such as increases in cholesterol or triglycerides, were mild, Kossoff noted.

After six months on the diet, 14 patients continued with it, even though the study was over, he said.

The findings are published in the February issue of the journal Epilepsia.

No one knows how the diet works to reduce seizures, Kossoff said. And, most people find it too hard to follow, so it's probably not a long-term solution for most people with epilepsy, he added.

He also noted that patients who go on the diet need to continue with it, perhaps for years to keep seizures under control.

But Kossoff thinks the diet can be simplified to make it easier to follow. "We are looking at less time in the clinic and fewer restrictions and without a dietitian," he said.

Dr. Gholam Motamedi, director of the epilepsy service at Georgetown University Hospital, thinks the diet can be useful for patients who have no other options.

"The study is promising, especially given that patients with refractory epilepsy in particular -- those who are not surgical candidates -- are left with not much hope," he said.

Normally, the plan for these patients is to try a combination of different drugs or to use vagus nerve stimulation, but none of these options offers much hope of seizure control, Motamedi said.

"Therefore, having another modality available is always welcomed by the neurologists," he said. "It also encourages basic research looking for insight to the underlying reasons for epilepsy."

More information

For more on epilepsy, visit the Epilepsy Foundation.

SOURCES: Eric H. Kossoff, M.D., assistant professor of neurology and pediatrics, Johns Hopkins University School of Medicine, Baltimore; Gholam Motamedi, M.D., associate professor of neurology, director, epilepsy service, Georgetown University Hospital, Washington, D.C.; February 2008, Epilepsia

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Modified Atkins diet can cut epileptic seizures in adults
2. Deafness and seizures result when mysterious protein deleted in mice
3. Former Sufferer of Rare Disease Called Musicogenic Epilepsy Thanks LIJ Medical Team That Ended Her Seizures and Gave Her Back the Gift of Music
4. UCB Announces FDA Filing for lacosamide in the Treatment of Partial Onset Seizures in Adults with Epilepsy
5. Some Epilepsy Patients Not Always Aware of Seizures
6. Lamotrigine May Reduce Epilepsy Seizures
7. Implantable device designed to detect, stop seizures under study at MCG
8. Alzheimers Patients May Suffer Silent Seizures
Post Your Comments:
Related Image:
Atkins-Like Diet Cuts Epileptic Seizures
(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of ... its next President and Chief Executive Officer, succeeding Dr. James C. Puffer upon his ... July 1, 2018 until Dr. Puffer’s retirement at the end of 2018. Upon assuming ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with ... for the primary prevention of cardiovascular diseases during the 15th Annual Women’s ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance ... care insurance companies have a waiver for care if the client has a cognitive ... the family pays for care, is often waived, so the benefits from their insurance ...
(Date:10/13/2017)... NJ (PRWEB) , ... October 13, 2017 , ... Global ... at scenic Alexandria Park in Milford, NJ. This free event, sponsored by Global ... physical activity. The fun run is geared towards children of all ages; it ...
(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... -- Halo Labs announces the European launch of their new low ... MIBio 2017 in Cambridge, U.K on October ... biopharmaceutical samples with unprecedented speed and sensitivity while using far less ... Imaging. ... analysis system ...
(Date:9/27/2017)... 2017  Commended for their devotion to personalized service, SMP ... number one in the South Florida Business Journal,s 50 Fastest-Growing ... yearly list, the national specialty pharmacy has found its niche.  ... will soon be honored by SFBJ as the 2017 Power ... Set to receive his award in October, Bardisa said of ...
(Date:9/23/2017)... Sept. 22, 2017 Janssen Biotech, Inc. (Janssen) ... letter from the U.S. Food and Drug Administration (FDA) ... sirukumab for the treatment of moderately to severely active ... clinical data are needed to further evaluate the safety ... active RA. ...
Breaking Medicine Technology: