Navigation Links
Atherosclerosis in abdominal aorta may signal future heart attack, stroke
Date:6/17/2013

OAK BROOK, Ill. In a study of more than 2,000 adults, researchers found that two MRI measurements of the abdominal aorta the amount of plaque in the vessel and the thickness of its wall are associated with future cardiovascular events, such as a heart attack or stroke. Results of the study are published online in the journal Radiology.

"This is an important study, because it demonstrates that atherosclerosis in an artery outside the heart is an independent predictor of adverse cardiovascular events," said the study's lead author, Christopher D. Maroules, M.D., a radiology resident at the University of Texas Southwestern Medical Center in Dallas and lead author. "MRI is a promising tool for quantifying atherosclerosis through plaque and arterial wall thickness measurements."

Atherosclerosis is a condition in which fat, cholesterol and other substances collect within the arteries, forming plaque. As plaque accumulates, the artery narrows, limiting blood flow. The condition can occur in any artery, including the cerebral (brain) and coronary (heart) arteries and the aorta, which carries oxygenated blood from the heart through the abdomen to the rest of body. The aorta is the largest artery body.

In the study, researchers analyzed abdominal MR images of 2,122 participants (mean age 44) in the Dallas Heart Study, a multiethnic population-based study of healthy adults from Dallas County, Texas. Two measurements were obtained from the MR images: mean abdominal aortic wall thickness, or the thickness of the vessel wall, and the amount of plaque buildup, referred to as the aortic plaque burden.

Following imaging, study participants were monitored for a period of 7.8 years. During that time, 143 participants experienced an adverse cardiovascular event in which arterial blood flow was obstructed, resulting in death or medical intervention. Researchers categorized the events as related to the heart (cardiac events) or to other arteries (called extra-cardiac vascular events) such as those in the brain or abdomen.

Of the 143 cardiovascular events, 34 were fatal. Seventy-three were non-fatal cardiac events, including heart attack or coronary revascularization, and 46 were non-fatal extra-cardiac vascular events, such as stroke or carotid revascularization.

Using the MRI measurements, the researchers found that increased abdominal aortic wall thickness correlated with a greater risk for all types of cardiovascular events. An increase in both wall thickness and aortic plaque burden was associated with an increased risk for non-fatal extra-cardiac vascular events.

"These MRI measurements may add additional prognostic value to traditional cardiac risk stratification models," Dr. Maroules said.

MR imaging of the abdominal aorta is less technically challenging than other vascular imaging exams because of the large size of the vessel and its lack of proximity to a moving organ, such as the heart or the lungs. In addition, images of the abdominal aorta are often captured when patients undergo other exams, such as MRI of the spine or abdomen.

"The abdominal aorta is incidentally imaged on a regular basis," Dr. Maroules said. "Radiologists can infer prognostic information from routine MRI exams that may benefit patients by identifying subclinical disease."

According to Dr. Maroules, further MRI research will contribute to a better understanding of the progression of atherosclerosis, which scientists believe begins with a remodeling or thickening of the vessel wall prior to the buildup of plaque.


'/>"/>

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

Related medicine news :

1. The search for an early biomarker to fight atherosclerosis
2. Atherosclerosis: Specific microRNAs promote inflammation
3. Islet transplant may slow progression of atherosclerosis
4. Autopsy-based study examines prevalence of atherosclerosis among US service members
5. Atherosclerosis found in HIV children
6. Researchers closer to understanding actions of cells involved in atherosclerosis
7. Cleveland Clinic researchers discover molecule that may prevent atherosclerosis
8. hCGTreatments/Diet Doc hCG Diets & Weight Loss Plans Announce New Customized Diet Plans that Target Trapped Abdominal Fat, Now Proven To Help Sharpen Cognitive Function
9. Iterative reconstruction plus longitudinal dose modulation reduces radiation dose for abdominal CT and save lives
10. Best Abdominal Exercise To See Faster Results From Kettlebell Workouts Video Revealed By StrongFirst Master Kettlebell Instructor Geoff Neupert
11. Abdominal Chemo Bath May Extend Survival in Ovarian Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... WI (PRWEB) , ... October 13, 2017 , ... As ... in medicine known as “patient engagement.” The patient is doing more than filling out ... partners. , “There is an increasing emphasis in health care and research on ...
(Date:10/13/2017)... , ... October 13, 2017 ... ... of Pharmacy (SOP) alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ... on guideline updates for the primary prevention of cardiovascular diseases during the ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional ... action towards gender equality at their inaugural Summit in New York City in June. ... a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... “The Journey: ... faced every danger possible to save lost souls in the Philippines. “The Journey: From ... Carole is a dedicated teacher of the Bible. She has taught all ages and ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... meet the demand of today’s consumer and regulatory authorities worldwide. From Children’s to ... and tested to meet the highest standard. , These products are also: ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... , Oct. 2, 2017  Eli Lilly and Company ... results for the third quarter of 2017 on Tuesday, ... call on that day with the investment community and ... The conference call will begin at 9 a.m. ... access a live webcast of the conference call through ...
(Date:10/2/2017)... The Rebound mobile app is poised to become a vital ... prescription drug addiction. The app empowers users to develop an ... their dosage in a safe, controlled manner while maximizing well-being. ... 100,000 people to sign up will enjoy 3 months of ... ...
(Date:9/27/2017)... , Sept. 27, 2017  Commended for their devotion to ... awards. Ranked as number one in the South Florida Business ... in Inc. 5000 yearly list, the national specialty pharmacy has ... Armando Bardisa will soon be honored by SFBJ as ... Set to receive his award in October, ...
Breaking Medicine Technology: