Navigation Links
Astrogenetix Narrows in on MRSA Virulence Onboard Discovery

Astrogenetix, an Austin, Texas-based commercial biotech company continues its microgravity research of MRSA on board Space Shuttle Discovery. The Company is validating target genes for MRSA virulence by sending up several different strains of the bacteria, which were genetically altered to remove target genes that are believed to be associated with virulence of this organism.

(Vocus) April 6, 2010 -- Astronauts on board Space Shuttle Discovery (STS-131) activated an experiment this morning as part of the ninth scientific payload for Astrogenetix, an Austin, Texas-based commercial biotech company. Astrogenetix is conducting the International Space Station National Laboratory Pathfinder Vaccine (NLP-V) missions to take advantage of the unique conditions of microgravity to uncover changes in bacteria that can be targeted to create new vaccines and therapeutics.

“Through this series of experiments, we are demonstrating that the International Space Station can be utilized as a platform for novel drug discovery,” said John Porter, Chief Executive Officer of Astrogenetix. “We sincerely believe the use of microgravity will yield tremendous benefits for new discovery to save lives on Earth.”

Astrogenetix has identified target genes for MRSA (a form of Staph infection) virulence by growing the bacteria in the microgravity environment during previous NLP-V missions. The Company is further examining and validating these genes on STS-131, by sending up several different strains of the bacteria, which were genetically altered to remove target genes that are believed to be associated with virulence of this organism.

MRSA is a type of bacteria that is not responsive to commonly used antibiotics and typically causes skin infections, but can also cause other infections – including pneumonia. In the past decade, infection and mortality due to this organism has increased drastically, exceeding the death rate for HIV. In the United States, MRSA is responsible for 100,000 cases of severe infections and more than 19,000 deaths annually.
“We’ve collected extraordinary data over the last several missions to the International Space Station, and we expect more critical data to come back with the Shuttle’s return,” added Dr. Jeanne Becker, Chief Science Officer for Astrogenetix. “We’re getting much closer to identifying a potential target for vaccine development by knocking out specific genes associated with virulence.”

Initial NLP-V studies conducted by Astrogenetix focused on developing a potential vaccine for Salmonella bacteria. Currently there is no vaccine for Salmonella, which represents a significant problem for food contamination in the U.S. and for American soldiers in foreign countries, in addition to causing illness and death in developing nations. Work conducted during the first three NLP-V spaceflight payloads resulted in the successful identification of key genes in Salmonella that could be manipulated to create a potential vaccine for this organism. The Company is developing an investigational new drug submission package for the U.S. Food and Drug Administration for subsequent initiation of trials for the Salmonella vaccine.

About Astrogenetix, Incorporated
A subsidiary of Astrotech Corporation (Nasdaq: ASTC), Astrogenetix is a biotechnology company formed to commercialize biotechnology products processed in the unique environment of microgravity. The Company offers a turn-key platform for pre-flight sample preparation, flight hardware, mission planning and operations, crew training and certification processes needed within the highly regulated and complex environment of manned space flight.

The statements in this document may contain forward-looking statements that are made pursuant to the Safe Harbor provisions of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements are subject to risks, trends, and uncertainties that could cause actual results to be materially different from the forward-looking statement. These factors include, but are not limited to, continued government support and funding for key space programs, product performance and market acceptance of products and services, as well as other risk factors and business considerations described in the company's Securities & Exchange Commission filings including the annual report on Form 10-K. Any forward-looking statements in this document should be evaluated in light of these important risk factors. The Company assumes no obligation to update these forward-looking statements.


Read the full story at

Source: PRWeb
Copyright©2010 Vocus, Inc.
All rights reserved  

Related medicine news :

1. Violent crime race gap narrows, but persists in US
2. Discovery Health and National Organization for Rare Disorders Partner for Second Annual Rare Disease Day With the Premiere of the Special DISEASE DETECTIVES
3. Molecule Discovery Might Help ALS Patients
4. Discovery Healths New Year, New You Week Brings Transformation and Inspiration to the Resolution Season
5. Discovery points way for new treatment for aneurysms: UBC-Providence Research
6. Discovery of mechanism in brain cell injury in Huntingtons offers new treatment approaches
7. Discovery Links Genes to Pancreatic Cancer
8. Discovery of epigenetic memory during breast cancer
9. Largest academic-industry collaboration for drug discovery in depression and schizophrenia launched
10. Case Western Reserve researchers new pathway discovery published as Paper of the Week
11. Winter Issue of Discoverys Edge
Post Your Comments:
Related Image:
Astrogenetix Narrows in on MRSA Virulence Onboard Discovery
(Date:11/25/2015)... ... November 25, 2015 , ... Smiles by Stevens is pleased ... moderate facial wrinkling. While many patients are aware of the benefits of Botox® in ... delivers to those suffering with discomfort, soreness, and pain as a result of Jaw ...
(Date:11/25/2015)... ... ... Beddit® has launched a new Android app for use with ... more intuitive SleepScore™ that rates sleep quality on a 100-point scale and makes it ... a proprietary algorithm. Beddit analyzes the data to provide an easy to understand scientific ...
(Date:11/25/2015)... Livonia, MI (PRWEB) , ... November 25, 2015 , ... ... at Presence Resurrection Medical Center (RMC) in Chicago, IL, UV Angel is evaluating the ... the medical and surgical intensive care units (totaling 30 beds) from May 2014 through ...
(Date:11/25/2015)... , ... November 25, 2015 , ... Today, Mothers ... our nation’s roadways has dropped below 10,000 for the first time since 2011. In ... 2013. , According to data released by the National Highway Traffic Safety Administration (NHTSA), ...
(Date:11/25/2015)... Md (PRWEB) , ... November 25, 2015 , ... ... Hypertension Association (PHA) announces the nation’s Periwinkle Pioneers, individuals and groups responsible for ... of this disease. The Periwinkle Pioneers, nominated by the public, will receive special ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... NEW DELHI , November 25, 2015 ... fear invoked due to repeated failure of IVF cycles. ... Rani Bhatia was totally dejected and had lost all hopes that ... the first Indian miracle child conceived after failure of ... to abroad (UK) before they decided to take one last ...
(Date:11/24/2015)... 2015  Array BioPharma Inc. (Nasdaq: ARRY ... Ron Squarer , will present at the ... The public is welcome to participate in the ... website.Event:Piper Jaffray Annual Healthcare ConferencePresenter:  , Ron Squarer, ... p.m. Eastern Time Webcast: , ...
(Date:11/24/2015)... , 24. November 2015 Avery ... Pacemaker Systems, ist erfreut, die Berufung von ... bekannt geben zu können. ... --> Foto - ... (Schweden). Von 1984-1986 war er Fellow des ...
Breaking Medicine Technology: