Navigation Links
AstraZeneca Studies Show Relief of Nighttime Heartburn and Reduction in GERD-Related Sleep Disturbances
Date:6/2/2009

p disturbances were defined as trouble sleeping due to heartburn and other symptoms of GERD.

In one study, relief of nighttime heartburn was significantly greater for patients treated with NEXIUM 20 mg once daily (n=137) compared with placebo (n=125) after four weeks (34.3% vs. 10.4%, P < .0001)(1). In addition, relief of GERD-related sleep disturbances was significantly greater for patients treated with NEXIUM 20 mg once daily compared with placebo (71.5% vs. 55.2%, P=.006)(1).

In a second four-week study, 84% of patients experienced relief of GERD-related sleep disturbances with NEXIUM 20 mg once daily (n=220) compared to 54% with placebo (n=221; P < .0001). In addition, relief of nighttime heartburn was significantly greater for patients treated with NEXIUM 20 mg once daily compared with placebo (50% vs 13% , P < .0001).

NEXIUM is contraindicated in patients with known hypersensitivity to any component of the formulation or to substituted benzimidazoles. The most frequently reported adverse reactions with NEXIUM include headache, diarrhea, and abdominal pain. Symptomatic response to therapy does not preclude the presence of gastric malignancy.

Please visit www.nexium-us.com or call 1-800-236-9933 for the NEXIUM full Prescribing Information.

About the Studies

The multicenter, randomized, double-blind, placebo-controlled study was conducted in 262 patients, male and female, ages 18 to 85 years old. All patients had at least a three-month history of heartburn and at least a one-month history of sleep disturbances associated with GERD. Patients received either NEXIUM 20 mg once daily or placebo for four weeks(1).

Nighttime heartburn symptom frequency and severity were assessed using a daily diary card. The primary end point, relief of nighttime heartburn, was defined as a daily diary card
'/>"/>

SOURCE AstraZeneca
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related medicine news :

1. AstraZeneca Leads Local Walking Movement
2. AstraZeneca Joins Local Walking Movement
3. Major Pharma Clinical Case Studies From Amgen, AstraZeneca, GSK, Intermune, Cephalon Inc, Sunesis Pharmaceuticals and Dartmouth Medical School During Fall Clinical Focused Programs
4. Verus Pharmaceuticals Announces Divestiture of Pediatric Asthma Development Programs to AstraZeneca
5. AstraZeneca Recognized as One of Working Mothers 100 Best Companies for the Sixth Consecutive Year
6. AstraZeneca Launches New Program to Support Facilities that Connect People to Needed Medical Care and Prescription Assistance
7. NPS Sells Assets Related to mGluR Collaboration to AstraZeneca for $30 Million to Support Late-Stage Product Development
8. Everett-Area Cancer Patients Can More Easily Navigate Health Care System Thanks to the American Cancer Society and AstraZeneca
9. Perrigo Announces that Dexcels Settlement with AstraZeneca Allows OTC Omeprazole Launch Following Final FDA Approval
10. AstraZeneca Response to November 2, 2007 Ruling In Re: Pharmaceutical Industry Average Wholesale Price Litigation, MDL No. 1456, U.S. District Court, District of Massachusetts
11. AstraZeneca Receives Six Months Pediatric Exclusivity Patent Extension for ARIMIDEX(R) (anastrozole) from the FDA
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/16/2009)... If proposed health care legislation is enacted, it ... system. Approximately 18.4 million Californians and 161 million ... employer-based insurance for their health care coverage. ... legislation entail specific requirements for employer-based insurance. ... firms that currently comply with most new standards, ...
(Date:12/16/2009)... Raises Significant Funds to Benefit of Children with Autism ... Taylor, Gary Cole and Zachary Levi Join Ben Stiller ... ANGELES, Dec. 16 At its 13th annual ... individuals. Hasbro President & CEO Brian ... in recognition of his far-reaching philanthropic leadership and commitment ...
(Date:12/16/2009)... -- Immucor, Inc. (Nasdaq: BLUD ), a global ... transfusion industry, today announced that Paul D. Mintz, M.D. ... independent director, effective January 1, 2010. ,, Dr. ... medicine for more than 30 years. He is a ... of Virginia School of Medicine. He also serves as ...
(Date:12/16/2009)... The most widely used human embryonic stem cell ... justice questions that must be addressed to ensure that ... according to a University of Michigan research team. ,, ... U-M team analyzed 47 embryonic stem cell lines, including ... researchers. The scientists determined the genetic ancestry of each ...
(Date:12/16/2009)... Scientists pinpoint seven that increase susceptibility to disease ... genes associated with increased susceptibility to leprosy have ... , The researchers, who analyzed more than 10,000 ... in China, said their discovery highlights the important ... the development of leprosy. , "Though leprosy is ...
Breaking Medicine News(10 mins):Health News:How National Health Reform Proposals Would Affect Employer-Based Plans in California 2Health News:How National Health Reform Proposals Would Affect Employer-Based Plans in California 3Health News:The Help Group Honors Brian Goldner, Mary Urquhart and Max Mayer at its Teddy Bear Ball Featuring Ben Stiller and Celebrity Guests 2Health News:The Help Group Honors Brian Goldner, Mary Urquhart and Max Mayer at its Teddy Bear Ball Featuring Ben Stiller and Celebrity Guests 3Health News:The Help Group Honors Brian Goldner, Mary Urquhart and Max Mayer at its Teddy Bear Ball Featuring Ben Stiller and Celebrity Guests 4Health News:The Help Group Honors Brian Goldner, Mary Urquhart and Max Mayer at its Teddy Bear Ball Featuring Ben Stiller and Celebrity Guests 5Health News:Immucor Appoints New Board Director 2Health News:U-M Study Reveals Surprising Lack of Genetic Diversity in the Most Widely Used Human Embryonic Stem Cell Lines 2Health News:U-M Study Reveals Surprising Lack of Genetic Diversity in the Most Widely Used Human Embryonic Stem Cell Lines 3Health News:U-M Study Reveals Surprising Lack of Genetic Diversity in the Most Widely Used Human Embryonic Stem Cell Lines 4Health News:U-M Study Reveals Surprising Lack of Genetic Diversity in the Most Widely Used Human Embryonic Stem Cell Lines 5Health News:Leprosy Genes Identified 2
... by Avalere Health found that nearly 30% of long-term ... higher than amounts reported in widely used previous estimates. ... assisted living, a key component of long-term care.This analysis, ... that individuals and their families contributed an estimated $64 ...
... Bio-Optronics, Inc., a leader in healthcare workflow ... solution, the only comprehensive, flexible, and easy-to-use patient ... capability.The Joint Commission,s #1 patient safety goal is ... ID bands are difficult to read and time-consuming ...
... Philadelphia, 5 March 2009 The new medical subspecialty ... the way in providing technically advanced yet cost-effective care ... in the March issue of the Journal of ... the Heart Failure Society of America (HFSA) and the ...
... Connecticut,s Largest Home Care Agencies Automates and Connects ... 5 Allscripts announced today that VNA HealthCare, ... Homecare as its electronic home care system. VNA ... independent living services to 60 communities in the ...
... only specialized clinic furthers AED industry-leading commitment to ... 67th annual meeting of the American Academy of ... Inc. (Nasdaq: SLTM ) today announced ... to advance the company,s new product development, facilitate ...
... United States and Canadian Academy of Pathology (USCAP)SUNNYVALE, ... the Elekta Group and leading provider of software ... the introduction of PowerPath version 9.3, including new ... at USCAP conference in Boston, March 9-11, 2009. ...
Other Medicine News:Health News:Almost 30% of Long-Term Care is Financed Out-of-Pocket, Report Finds 2Health News:bioPoint(TM) PID Wristband Software Improves Patient Identification Accuracy and Safety 2Health News:New specialty to focus on advanced heart failure and heart transplantation 2Health News:VNA HealthCare Selects Allscripts Homecare 2Health News:VNA HealthCare Selects Allscripts Homecare 3Health News:VNA HealthCare Selects Allscripts Homecare 4Health News:VNA HealthCare Selects Allscripts Homecare 5Health News:Solta Medical, Inc. Announces State-of-the-Art Aesthetic Center 2Health News:Solta Medical, Inc. Announces State-of-the-Art Aesthetic Center 3Health News:Impac Software Introduces PowerPath(R) Version 9.3 AT USCAP 2Health News:Impac Software Introduces PowerPath(R) Version 9.3 AT USCAP 3
(Date:12/16/2009)... N.J., Dec. 16 Ethicon, Inc., a ... company and a worldwide leader in surgical care, ... company dedicated to designing, developing and commercializing devices ... throat (ENT), today announced a definitive merger agreement ... transaction for approximately $785 million net of estimated ...
(Date:12/16/2009)... LAKE FOREST, Ill., Dec. 16 Hospira, Inc. ... pharmaceutical and medication delivery company, today announced that it ... and full-year 2009 results and projections for 2010 on ... ,, The company will release its fourth-quarter and full-year ... market open and the conference call. ,, A live ...
(Date:12/16/2009)... 16 International, well-known,scientific experts ... GFT505 (80 mg/day),data presented as "extremely ... scientists and clinicians critically reviewed these ... of generic lipid-modifying,treatments, fenofibrate and bezafibrate, ... observed in patients with metabolic syndrome,and ...
Breaking Medicine Technology:Ethicon Announces Definitive Agreement to Acquire Acclarent 2Ethicon Announces Definitive Agreement to Acquire Acclarent 3Ethicon Announces Definitive Agreement to Acquire Acclarent 4International, Well-Known Scientific Experts Say That New GFT505 Data Unlikely to Have the Potential to Affect the Established Role of Generic Fenofibrate and Bezafibrate in Managing Atherogenic Dyslipidemia 2International, Well-Known Scientific Experts Say That New GFT505 Data Unlikely to Have the Potential to Affect the Established Role of Generic Fenofibrate and Bezafibrate in Managing Atherogenic Dyslipidemia 3Pitt researchers harness carbon nanomaterials for drug delivery systems oxygen sensors 54668 1Pitt researchers harness carbon nanomaterials for drug delivery systems oxygen sensors 54668 2American Lung Association in Florida Joins Anti Recession Campaign by Forming Strategic Alliance With www i am anti recession com 54664 1American Lung Association in Florida Joins Anti Recession Campaign by Forming Strategic Alliance With www i am anti recession com 54664 2Study shows how to boost value of Alzheimers fighting compounds 54660 1Study shows how to boost value of Alzheimers fighting compounds 54660 2
... University graduate student has found a correlation between childhood obesity ... doctoral student in human nutrition, Manhattan, conducted research that found that ... of physical activity had greater amounts of airway narrowing after exercise. ... and inactive are having -- even at the age of 8 ...
... LONDON, Dec. 11 On December 11, 2008, ... and Drug Administration (FDA) - including the Drug ... Advisory Committee, and the Pulmonary-Allergy Drugs Advisory Committee ... risks of asthma medications containing long-acting beta-agonists (LABAs). ...
Other Medicine Technology:K-State Researcher Finds Correlation Between Childhood Obesity and Asthma 2K-State Researcher Finds Correlation Between Childhood Obesity and Asthma 3AstraZeneca Responds to FDA Joint Advisory Committees' Recommendation on SYMBICORT(R) 2AstraZeneca Responds to FDA Joint Advisory Committees' Recommendation on SYMBICORT(R) 3AstraZeneca Responds to FDA Joint Advisory Committees' Recommendation on SYMBICORT(R) 4
... Liquichek™ Reticulocyte Stain is ... stain for use in manual ... liquid product has a one ... at 230C and can be ...
Seroconversion and Antigen Panel Chart...
... CT/GC Controls are liquid controls ... of test procedures that detect ... Since they are specimen specific, ... either urine or endocervical/urethral swabs ...
Liquichek Autoimmune Controls are individual controls for monitoring the performance of autoimmune assays....
Medicine Products: