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AstraZeneca Announces SEROQUEL XR is Now Available to Treat Bipolar Depression
Date:2/23/2009

SEROQUEL XR is Now Approved to Treat the Depressive, Manic, and Mixed Episodes of Bipolar Disorder

WILMINGTON, Del., Feb. 23 /PRNewswire-FirstCall/ -- AstraZeneca (NYSE: AZN) today launched its once-daily SEROQUEL XR(R) (quetiapine fumarate) Extended-Release Tablets for the acute treatment of the depressive episodes associated with bipolar disorder and the manic and mixed episodes associated with bipolar I disorder, as well as the maintenance treatment of bipolar I disorder as adjunctive therapy to lithium or divalproex. SEROQUEL XR is also now available in two new tablet strengths, 50-mg and 150-mg.(1)

Once-daily SEROQUEL XR is the only medication FDA-approved for the treatment of acute depressive, manic, and mixed episodes of bipolar disorder.(2)

"Bipolar depression is a serious and debilitating illness with few approved treatment options," said Dr. Trisha Suppes, Professor of Psychiatry and Behavioral Sciences, Stanford University Medical Center and VA Palo Alto Health Care System. "People with bipolar disorder are known to struggle more frequently with the depressive rather than the manic symptoms. SEROQUEL XR has been shown to be effective as a monotherapy in treating bipolar depressive symptoms, such as sadness, loss of interest, and feelings of worthlessness."

Approximately 8 million American adults may be affected by bipolar disorder, also known as manic-depressive illness, a serious psychiatric condition characterized by recurring episodes of depression and mania.(3,4) For many patients with bipolar disorder, the depressive symptoms are more disruptive than the manic symptoms.(5)

"When symptomatic, people with bipolar disorder experience depressive symptoms more than three times longer than man
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SOURCE AstraZeneca
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