Navigation Links
Association of fiber and colorectal cancer risk differs depending on dietary assessment method
Date:4/20/2010

High dietary fiber intake was associated with a lower risk of colorectal cancer when researchers used data from food diaries but not when they used data obtained from food frequency questionnaires, according to a study published online April 20 in the Journal of the National Cancer Institute.

Previous studies have examined the issue of dietary fiber and risk of colorectal cancer, but the results have been inconsistent, particularly in studies that used food-frequency questionnaires (FFQs).

In this study, Christina Dahm Ph.D., and Kay-Tee Khaw, MBBChir., of the University of Cambridge in the UK, and colleagues used data obtained from both food diaries and food frequency questionnaires to estimate fiber intake. Their prospective, casecontrol study was nested within seven UK cohort studies and included 579 patients who developed colorectal cancer more than 1 year after they began keeping the food diaries. These case patients' fiber intake was compared with that of 1,996 control subjects who did not develop colorectal cancer. Case and control subjects were matched for sex, age, and date of diary completion.

The researchers found that participants who had higher intakes of fiber, ascertained by food diaries, were less likely to develop colorectal cancer than those with lower intakes. For individuals who consumed an average of 24 grams per day of dietary fiber, the odds of developing colorectal cancer were 30% lower than for those who consumed an average 10 grams per day. The difference was statistically significant and consistent even after the researchers took into account other risk factors for colorectal cancer, such as age, physical activity, and intakes of alcohol and red meats.

However, when the researchers performed the same analysis using data obtained from the food frequency questionnaires, they found no statistically significant association between fiber intake and the risk of colorectal cancer.

"These findings strengthen existing evidence that supports recommendations to increase dietary fiber intake in populations to reduce colorectal cancer incidence," the authors write. They suggest that "the fact that we found no association usingthe FFQ may explain the lack of convincing evidence relating fiber intake to a substantial reduction in colorectal cancer risk in some previous studies that relied on FFQs."

In an accompanying editorial, Ross Prentice, Ph.D., of the Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, notes that accurate measurement of dietary components remains a major challenge in studies of diet and cancer risk. He calls for the development of biological markers to measure intake more accurately. "The explicit use of biomarkers to correct nutritional epidemiology associations for systematic and random measurement error in dietary assessment seems a logical next step in the nutritional epidemiology research agenda," he writes.


'/>"/>

Contact: Caroline McNeil
jncimedia@oxfordjournals.org
301-841-1286
Journal of the National Cancer Institute
Source:Eurekalert

Related medicine news :

1. Respiratory Therapist School, Pima Medical Institute, Donates Time, Money to American Lung Association
2. The association between sleep disturbances and reduced quality of life varies by race
3. Health Forum / American Hospital Association 2010 Leadership Summit
4. American Association of Diabetes Educators Selects GES
5. The Association for Molecular Pathology celebrates ruling in DNA patent case
6. Health Care Reform Law Could Improve Children's Oral Health, states Delta Dental Plans Association
7. Feeding America's David Arquette and Courteney Cox Team Up With the National Association of Letter Carriers to Stamp Out Hunger™
8. National Debt Relief Group Celebrates Proud Membership with TASC (The Association for Settlement Companies)
9. Grand Canyon University Nursing School Announces Three-Year Partnership with American Heart Association
10. The American Heart Association's The Heart of Diabetes Campaign is Helping Patients 'Know Your Diabetes' Better
11. National Medical Association, Health System Reform - From Legislation to Implementation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... ... March 29, 2017 , ... The Thyroid Secret is a ... FASCP. The program was recently launched on March 1, and Dr. Wentz discussed ... , Dr. Izabella Wentz is a licensed pharmacist and a foremost thyroid ...
(Date:3/28/2017)... ... March 28, 2017 , ... City trips ... (IBT World Travel Trends Report). As travelers visit both urban destinations, they are ... and prolonged sun exposure. In response, the outdoor industry has blurred the lines ...
(Date:3/28/2017)... ... March 28, 2017 , ... ... advancing the science and clinical practice of radiosurgery, announced today the publication ... multi-institutional, observational registry established to standardize data collection from patients treated with ...
(Date:3/28/2017)... ... ... Sentry Group LLC., a leader in the Personal Emergency Response System industry, introduced advanced ... These iSAFE products are the most affordable and most advanced medical alert systems on ... GPS Location and two-way calling with the push of a button on a nationwide ...
(Date:3/28/2017)... (PRWEB) , ... March 28, 2017 , ... WHO: , ... Toni Bark , WHAT: , Medical doctors and PhD scientists will speak to the ... to President Trump in support of an independent vaccine safety commission. , WHERE: ...
Breaking Medicine News(10 mins):
(Date:3/29/2017)... USA, March 29, 2017 Stryker announced today ... by People magazine, in partnership with Great Place to ... on the list. This list highlights the top U.S. ... in business while also demonstrating respect, compassion and concern ... To determine the companies on the list, ...
(Date:3/29/2017)... FinancialBuzz.com News Commentary  ... Data published in a research report by Grand View Research, ... of USD 55.8 billion by 2025. The projection takes into consideration the ... and a more open approach towards cannabis products around the world. In ... , North Dakota , Ohio , ...
(Date:3/29/2017)... , Mar. 29, 2017 Research and ... and Risk Management Software Market Outlook: 2016-2022" report to their ... The ... by product, mode of delivery, end-user, and geography. ... systems across the globe. The field has developed significantly in the ...
Breaking Medicine Technology: