Navigation Links
Assessing the value of treatments to increase height
Date:3/31/2011

CLEVELAND -- Dr. Leona Cuttler, a pediatric endocrinologist and growth hormone expert from University Hospitals Rainbow Babies and Children's Hospital, is the co-author of an editorial in the New England Journal of Medicine commenting on a new study that found giving girls with Turner syndrome low doses of estrogen, as well as growth hormone, years before the onset of puberty, increases their height and offers other benefits.

With her co-author Dr. Robert L. Rosenfield, a pediatric endocrinologist with the University of Chicago Medical Center, Dr. Cuttler writes, "The use of growth hormone and estrogen has a long and often controversial history in the manipulation of growth."

About the new study, they write that the results confirm those of previous, less rigorous studies showing that treatment with growth hormone significantly increased adult height in patients with Turner's syndrome.

Drs. Cuttler and Rosenfield say the results suggest a modest but intriguing synergism between growth hormone and low-dose estrogen in promoting growth.

"The impact of these findings on practice and policy will depend not only on their statistical significance but also on whether the observed changes in height translate into clinically meaningful benefit. The ability to increase height should not be the sole yardstick for assessing benefit," the editorial states.

"Since growth hormone is well entrenched in the management of Turner's syndrome, the current findings support this aspect of practice but are not likely to change it. Yet the results underscore the need for a measured approach, which includes avoiding unrealistic expectations, when families embark on growth hormone therapy. The early use of low-dose estrogen in conjunction with growth hormone is an interesting possibility. An optimal estrogen-replacement regimen could potentially shorten the period of growth hormone treatment, reduce costs, and improve patient satisfact
'/>"/>

Contact: George Stamatis
george.stamatis@UHhospitals.org
216-844-3667
University Hospitals Case Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Mortality rates are an unreliable metric for assessing hospital quality, study finds
2. Assessing positive outcomes of phase III trials
3. Researchers validate a new test for assessing childrens and teenagers fitness to prevent morbidity
4. Assessing the science behind health claims
5. An appeal to the caregiving values of rural women for breast cancer prevention
6. Mayo Clinic researchers confirm value of therapeutic hypothermia after cardiac arrest
7. Study: Consumers value safer food more than current analyses suggest
8. Supporters and opponents of a special blessing for homosexuals share many values
9. Does Club Drug Ecstasy Have Therapeutic Value?
10. Brief clarifies Social Securitys value for women
11. Biological diversity of ovarian cancer lessens value of screening
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... Health Dialog, a leading provider of ... has received Patient Oriented Accreditation from the National ... Management (DM) Programs for asthma, congestive heart failure, ... and diabetes. This marks the 12th continuous year ... Management (DM) Programs, reaffirming Health Dialog’s focus and ...
(Date:12/15/2014)... Dec. 14, 2014 (HealthDay News) -- Expert pilots process ... explains why they make better decisions during landings, a ... most difficult techniques for pilots to master, and 36 ... fatal crashes occur during final approach and landing. ... and 12 moderately experienced pilots while they were at ...
(Date:12/15/2014)... 2014 Kathy McAfee, America's Marketing Motivator, ... Awards in the category of Best Blog 2014. McAfee ... her weekly career blog Networking Ahead which ... professionals elevate their talent and influence through better networking, ... her book Networking Ahead for Business, has been motivating ...
(Date:12/15/2014)... OR (PRWEB) December 15, 2014 ... seeks to bring attention to restrictive state laws ... position paper on this important area of public ... Laws Can Compromise the Integrity of Independent Review, ... and access of independent peer review determinations can ...
(Date:12/15/2014)... Bacteroides is becoming the indicator of choice for ... prevalent than coliforms, it cannot reproduce in the presence of ... Key Benefits of the new Bacteroides Sewage Screen:, ... Eliminates false positives from coliforms naturally occurring in the environment ... Maintain the same sampling method with results as quick ...
Breaking Medicine News(10 mins):Health News:Health Dialog Receives NCQA Accreditation for Disease Management Programs 2Health News:Study Shows Why Expert Pilots Are Experts 2Health News:Kathy McAfee, America’s Marketing Motivator, Wins Best Blog from Women World Awards 2Health News:NAIRO Calls for Higher Quality Independent Peer Review By Ending Restrictive State Laws 2
... can learn the approaches and methods used to diagnose ... 34th Annual Pulmonary & Allergy Update conference hosted February ... by National Jewish professors Harold Nelson, MD, Erwin Gelfand, ... interact with the world,s leading specialists. "For three ...
... -- Racial and cultural factors still affect the diagnosis and ... tools and therapies in recent decades, according to a new ... to be diagnosed -- and therefore treated -- than whites ... in the United States have an episode of major depression ...
... , TUESDAY, Dec. 27 (HealthDay News) -- Poor ... the suffering of others and to show compassion, according to ... adults who were divided into groups that took part in ... compassion. The findings challenge previous research that concluded lower-class ...
... Another potential obstacle to developing an HIV vaccine ... known as the STEP study was halted in September ... not work. Moreover, subsequent analyses indicated that the vaccine ... individuals who had pre-existing immune effectors (antibodies) that recognized ...
... childhood, rituals like regular schedules for meal, bath, and ... But combined with oral and tactile sensitivities, such as ... fabrics, these rituals could be an early warning sign ... to Prof. Reuven Dar of Tel Aviv University,s Department ...
... 26 (HealthDay News) -- Quitting smoking is one of ... said than done, with six of 10 smokers requiring ... the American Lung Association. However, preparing a quit-smoking ... "Quitting smoking is the single most important step smokers ...
Cached Medicine News:Health News:Racial Disparities Seem to Persist in Depression Diagnosis 2Health News:Poor People May Be Quicker to Be Kind 2Health News:JCI online early table of contents: Dec. 27, 2011 2Health News:JCI online early table of contents: Dec. 27, 2011 3Health News:JCI online early table of contents: Dec. 27, 2011 4Health News:JCI online early table of contents: Dec. 27, 2011 5Health News:JCI online early table of contents: Dec. 27, 2011 6Health News:JCI online early table of contents: Dec. 27, 2011 7Health News:JCI online early table of contents: Dec. 27, 2011 8Health News:Childhood hypersensitivity linked to OCD 2Health News:How to Make Your Quit-Smoking Resolution Stick 2
(Date:12/17/2014)... and RALEIGH, N.C. , Dec. ... LLC (CTMC), and Integrated Clinical Trial Services, LLC ... retention for clinical trials announce that they have ... Marketing Services (i-CTMS). i-CTMS will provide a broad ... pharmaceutical, biotechnology and medical device companies. ...
(Date:12/15/2014)... and Markets ( http://www.researchandmarkets.com/research/bf3b6l/electrocardiogram ) has announced ... Global Trends, Estimates and Forecasts, 2012-2018" report to ... Global Electrocardiogram Devices (ECG) sector is projected ... North America accounts for nearly 36% (2015) ... claims approximately 27% (2018). Asia-Pacific ...
(Date:12/15/2014)... HERZLIYA PITUACH, Israel , Dec. 15, 2014 ... IMNP ) announced today that its Board of Directors has ... Daniel Teper who continues as Chief Executive Officer ... Board of Directors since 2013. Immune,s new Chairman, ... represent the interest of shareholders and to continue to support ...
Breaking Medicine Technology:Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 2Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 3Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 2Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 3Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 4Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 2Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 3Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 4
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: