Navigation Links
Aspirin may counteract potential trans fat-related stroke risk in older women
Date:2/29/2012

Older women whose diets include a substantial amount of trans fats are more likely than their counterparts to suffer an ischemic stroke, a new study shows.

However, the risk of stroke associated with trans fat intake was lower among women taking aspirin, according to the findings from University of North Carolina at Chapel Hill researchers.

The study, "Trans Fat Intake, Aspirin and Ischemic Stroke Among Postmenopausal Women," was published Thursday (March 1, 2012) online in the journal Annals of Neurology.

The study of 87,025 generally healthy postmenopausal women aged 50 to 79 found that those whose diets contained the largest amounts of trans fats were 39 percent more likely to have an ischemic stroke (clots in vessels supplying blood to the brain) than women who ate the least amount of trans fat. The risk was even more pronounced among non-users of aspirin: those who ate the most trans fat were 66 percent more likely to have an ischemic stroke than females who ate the least trans fat.

However, among women who took aspirin over an extended period of time, researchers found no association between trans fat consumption and stroke risk suggesting that regular aspirin use may counteract trans fat intake's adverse effect on stroke risk among women.

Trans fat is generally created in the food production process and is found in commercially prepared foods, including many shortenings, cake mixes, fried fast foods, commercially baked products (such as doughnuts, cakes and pies), chips, cookies and cereals.

Researchers from the UNC Gillings School of Global Public Health studied women who were enrolled in the Women's Health Initiative Observational Study. From 1994 to 2005, 1,049 new cases of ischemic stroke were documented.

Women who consumed the highest amount of trans fat also were more likely to be smokers, have diabetes, be physically inactive and have lower socioeconomic status than those who consumed the least trans fat, the study showed.

"Our findings were contrary to at least two other large studies of ischemic stroke," said Ka He, Sc.D., M.D., associate professor of nutrition and epidemiology at the UNC public health school. "However, ours was a larger study and included twice as many cases of ischemic stroke. Our unique study base of older women may have increased our ability to detect the association between trans fat intake and ischemic stroke among non-users of aspirin."

He said aspirin may lower the risk of ischemic stroke because of its anti-inflammatory and anti-platelet clumping properties.

The UNC researchers did not find any association between eating other kinds of fat (including saturated, monounsaturated or polyunsaturated fat) and ischemic strokes.

"Our findings highlight the importance of limiting the amount of dietary trans fat intake and using aspirin for primary ischemic stroke prevention among women, especially among postmenopausal women who have elevated risk of ischemic stroke," said lead author Sirin Yaemsiri, a doctoral student in the school's epidemiology department.


'/>"/>
Contact: patric lane
patric_lane@unc.edu
919-962-8596
University of North Carolina at Chapel Hill
Source:Eurekalert

Related medicine news :

1. New hybrid NOSH aspirin as possible anti-cancer drug
2. Aspirin as Good as Plavix for Poor Leg Circulation: Study
3. Experimental Drug Might Beat Aspirin in Preventing Repeat Strokes: Study
4. Low-Dose Aspirin to Prevent First Heart Attack or Stroke? Not So Fast
5. Could Daily Aspirin Harm Seniors Eyes?
6. Low-Dose Aspirin After Lung Clot Could Prevent Recurrence
7. Preoperative aspirin therapy can benefit cardiac surgery patients
8. Daily Aspirin May Help Prevent Colon Cancer for Those at High Risk
9. Scientists prove regular aspirin intake halves cancer risk
10. Even low-dose aspirin may increase risk of GI bleeding
11. No Proof That Aspirin Aids Conception, Review Shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2017)... (PRWEB) , ... April 29, 2017 , ... ... celebrate the profession and recognize the positive impact veterinarians have on animal health ... and the World Organization for Animal Health (OIE) choose a theme each year ...
(Date:4/28/2017)... NC (PRWEB) , ... April 28, 2017 , ... ... announce its new partnership with the Home Care Association of America (HCAOA). This ... and Private Duty Accreditation services, as well as discounts on Accreditation University (AU) ...
(Date:4/28/2017)... (PRWEB) , ... April 28, 2017 , ... Beginning in ... of their formulas. This begins with the popular ClearLungs Extra Strength formula. To ensure ... changing the formula in the following ways:, , Removal of ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... distribution of the GlycoMark test throughout the Northeast U.S. , GlycoMark is ... with diabetes. The GlycoMark test provides a clinically proven one- to two-week measure ...
(Date:4/28/2017)... Fairfax, VA (PRWEB) , ... April 28, 2017 , ... ... elected volunteer board members and officers for 2017-2018. The annual board election process has ... serving on a volunteer basis. , Thomas C. Dickerson, Ed.D., FACHE, succeeds Jim Hamilton, ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... MINNEAPOLIS , April 20, 2017  Cogentix ... company focused on providing the Urology, Uro/Gyn and ... reported that Ash Keswani has joined the Company ... In this newly created position, Mr. Keswani will ... and CEO. "Our organization is delighted ...
(Date:4/20/2017)... Research and Markets has announced the addition of the ... Market and Increasing Usage of Complex Biologics during the Forecast Period" ... ... 20 Billion in 2015 to around USD 26 Billion by 2020. ... by Rapidly Expanding Injectables Market and Increasing Usage of Complex Biologics ...
(Date:4/20/2017)... 20, 2017 Eyevensys, a private ... non-viral gene expression technology that enables the safe, local, ... address a wide range of ophthalmic diseases, announces it ... products Regulatory Agency (MHRA) to advance its technology into ... ...
Breaking Medicine Technology: