Navigation Links
Aspirin may counteract potential trans fat-related stroke risk in older women
Date:2/29/2012

Older women whose diets include a substantial amount of trans fats are more likely than their counterparts to suffer an ischemic stroke, a new study shows.

However, the risk of stroke associated with trans fat intake was lower among women taking aspirin, according to the findings from University of North Carolina at Chapel Hill researchers.

The study, "Trans Fat Intake, Aspirin and Ischemic Stroke Among Postmenopausal Women," was published Thursday (March 1, 2012) online in the journal Annals of Neurology.

The study of 87,025 generally healthy postmenopausal women aged 50 to 79 found that those whose diets contained the largest amounts of trans fats were 39 percent more likely to have an ischemic stroke (clots in vessels supplying blood to the brain) than women who ate the least amount of trans fat. The risk was even more pronounced among non-users of aspirin: those who ate the most trans fat were 66 percent more likely to have an ischemic stroke than females who ate the least trans fat.

However, among women who took aspirin over an extended period of time, researchers found no association between trans fat consumption and stroke risk suggesting that regular aspirin use may counteract trans fat intake's adverse effect on stroke risk among women.

Trans fat is generally created in the food production process and is found in commercially prepared foods, including many shortenings, cake mixes, fried fast foods, commercially baked products (such as doughnuts, cakes and pies), chips, cookies and cereals.

Researchers from the UNC Gillings School of Global Public Health studied women who were enrolled in the Women's Health Initiative Observational Study. From 1994 to 2005, 1,049 new cases of ischemic stroke were documented.

Women who consumed the highest amount of trans fat also were more likely to be smokers, have diabetes, be physically inactive and have lower socioeconomic status than those who consumed the least trans fat, the study showed.

"Our findings were contrary to at least two other large studies of ischemic stroke," said Ka He, Sc.D., M.D., associate professor of nutrition and epidemiology at the UNC public health school. "However, ours was a larger study and included twice as many cases of ischemic stroke. Our unique study base of older women may have increased our ability to detect the association between trans fat intake and ischemic stroke among non-users of aspirin."

He said aspirin may lower the risk of ischemic stroke because of its anti-inflammatory and anti-platelet clumping properties.

The UNC researchers did not find any association between eating other kinds of fat (including saturated, monounsaturated or polyunsaturated fat) and ischemic strokes.

"Our findings highlight the importance of limiting the amount of dietary trans fat intake and using aspirin for primary ischemic stroke prevention among women, especially among postmenopausal women who have elevated risk of ischemic stroke," said lead author Sirin Yaemsiri, a doctoral student in the school's epidemiology department.


'/>"/>
Contact: patric lane
patric_lane@unc.edu
919-962-8596
University of North Carolina at Chapel Hill
Source:Eurekalert

Related medicine news :

1. New hybrid NOSH aspirin as possible anti-cancer drug
2. Aspirin as Good as Plavix for Poor Leg Circulation: Study
3. Experimental Drug Might Beat Aspirin in Preventing Repeat Strokes: Study
4. Low-Dose Aspirin to Prevent First Heart Attack or Stroke? Not So Fast
5. Could Daily Aspirin Harm Seniors Eyes?
6. Low-Dose Aspirin After Lung Clot Could Prevent Recurrence
7. Preoperative aspirin therapy can benefit cardiac surgery patients
8. Daily Aspirin May Help Prevent Colon Cancer for Those at High Risk
9. Scientists prove regular aspirin intake halves cancer risk
10. Even low-dose aspirin may increase risk of GI bleeding
11. No Proof That Aspirin Aids Conception, Review Shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A Forever ... Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation ... as home to some of the world’s leading providers of cereal and other breakfast ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from ... at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center ... care topics including advance care planning, healthcare costs and patient and family engagement. ...
(Date:6/25/2016)... CA (PRWEB) , ... June 25, 2016 , ... As ... with Magna Cum Laude and his M.D from the David Geffen School of Medicine ... and returned to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive ...
(Date:6/24/2016)... Michigan (PRWEB) , ... June 24, 2016 , ... Those ... deal with these feelings, many turn to unhealthy avenues, such as drug or alcohol ... of Marne, Michigan, has released tools for healthy coping following a traumatic event. , ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all ... brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016  Collagen Matrix, Inc., ("Collagen Matrix") ... manufacturing of collagen and mineral based medical devices ... Bill Messer has joined the company ... leverage the growing portfolio of oral surgery, neurosurgery, ... Bill joins the Collagen Matrix executive team as ...
(Date:6/24/2016)... The Academy of Managed Care Pharmacy (AMCP) ... would allow biopharmaceutical companies to more easily share health ... and coverage decisions, a move that addresses the growing ... The recommendations address restrictions in the sharing of ... label, a prohibition that hinders decision makers from accessing ...
(Date:6/24/2016)... 24, 2016   Pulmatrix, Inc ., (NASDAQ: ... inhaled drugs, announced today that it was added to ... its comprehensive set of U.S. and global equity ... an important milestone for Pulmatrix," said Chief Executive Officer ... of our progress in developing drugs for crucial unmet ...
Breaking Medicine Technology: