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Aspirin at Bedtime Lowers Blood Pressure
Date:5/14/2008

No drop in blood pressure was found in those taking morning aspirin or following the general guidelines.

"There is some evidence that taking a variety of medications, including those for hypertension, at night is associated with greater blood pressure reduction than taking them in the morning," said Dr. Suzanne Oparil, president of the American Society for Hypertension. "I don't think we know why."

It's possible that there might be better absorption of the medication by the gastrointestinal tract at night, said Oparil, who is a professor of medicine at the University of Alabama at Birmingham.

"It's all a little bit speculative about why, but I think the observation is solid," she said.

In a statement, Hermida said the new findings "show us that we cannot underestimate the impact of the body's circadian rhythms."

"The beneficial effects of time-dependent administration of aspirin have until now been largely unknown in people with prehypertension," he said. "Personalizing treatment according to one's own rhythms gives us a new option to optimize blood pressure control and reduce the risk of cardiovascular disease down the line."

More information

Aspirin in all its aspects is described by the U.S. National Library of Medicine.



SOURCES: Suzanne Oparil, M.D., professor, medicine, University of Alabama at Birmingham; May 14, 2008, presentation, American Society of Hypertension annual meeting, New Orleans


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