Navigation Links
Aspirin May Increase Risk of Crohn's Disease
Date:5/3/2010

But experts add that painkiller's other health benefits may outweigh possible link

MONDAY, May 3 (HealthDay News) -- A new British study finds that people who take aspirin every day have a higher risk of developing Crohn's disease, a potentially devastating digestive illness.

But it's still not very likely that aspirin users will develop the condition, and the study's lead author said patients should keep in mind that aspirin lowers the risk of heart disease.

"If the link with aspirin is a true one, then only a small proportion of those who take aspirin -- approximately one in 2,000 -- may be at risk," said study author Dr. Andrew Hart, a senior lecturer in gastroenterology at University of East Anglia School of Medicine. "If aspirin has been prescribed to people with Crohn's disease or with a family history by their physician, then they should continue to take it. Aspirin has many beneficial effects and should be continued."

An estimated 500,000 people in the United States have Crohn's disease, which causes digestive problems and can boost the risk of bowel cancer. In some cases, patients must undergo surgery; many have to take medications for the rest of their lives.

While aspirin is known for its ability to reduce the risk of heart disease, it can cause stomach ulcers, and research in animals has suggested it can be hard on the intestines, too. The study authors decided to see if it had the same effect in humans, Hart said.

In the new study, researchers tracked 200,000 volunteers, aged 30 to 74, from several European countries.

The researchers found that aspirin use for a year or more boosted the risk of Crohn's disease by five times.

However, the study only suggests there's a link between aspirin use and the disease; it doesn't prove that aspirin actually increased the risk. And the researchers didn't know how much aspirin each person took.

Why might aspirin boost the risk of Crohn's disease? Dr. William J. Sandborn, vice chair of Mayo Clinic's Division of Gastroenterology and Hepatology, said it might have something to do with aspirin damaging the lining of the bowel, potentially triggering the condition in those who are susceptible to it because of their genetic makeup.

Sandborn, who's familiar with the findings, agreed with Hart that patients need to think about the benefits of aspirin use, including the reduced risk of not only heart disease but also colorectal cancer.

The study found no link between aspirin use and ulcerative colitis, another digestive disorder.

Future research is needed to confirm the aspirin-Crohn's disease link and determine what aspirin has to do with the higher risk, Hart said.

"If it does turn out to be a true link in the future, then it will be only one of many factors involved in causing Crohn's disease," he said. "Because aspirin has benefits, users should continue with it."

The study was to be presented Monday at the Digestive Disease Week conference in New Orleans.

More information

For more about Crohn's disease, see the U.S. National Library of Medicine.



-- Randy Dotinga



SOURCES: Andrew Hart, M.D, senior lecturer, gastroenterology, University of East Anglia School of Medicine, United Kingdom; William J. Sandborn, M.D., vice chair, division of gastroenterology and hepatology, Mayo Clinic, Rochester, Minn.; May 3, 2010, presentation, Digestive Disease Week conference, New Orleans


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. In Women, Aspirin Might Ward Off Eye Trouble
2. Aspirin During Pregnancy May Help Preemies
3. Three Anticoagulant Studies May Change Current Medical Practice Including New Data Revealing That Preventative Use of Aspirin and Heparin is Not Effective in Reducing Recurrent, Unexplained Miscarriages
4. Aspirin May Boost Breast Cancer Survival
5. Cardiologists Comment on Aspirin Versus Resveratrol
6. Aspirin Alone Works Best to Prevent Clots a Year After Stenting
7. Connecture, Inc. Launches New Technology Package to Increase Health Insurance Carriers' Success in the Online Individual Market
8. Cocaine or ecstasy consumption during adolescence increases risk of addiction
9. New Research Shows Genes of Pregnant Women and Their Fetuses Can Increase the Risk of Preterm Labor
10. Genes of pregnant women and their fetuses can increase the risk of preterm labor
11. NIH scientists identify maternal and fetal genes that increase preterm birth risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... "With 30 ... their specific project," said Christina Austin - CEO of Pixel Film Studios. , ... and all within Final Cut Pro X . Simply select a ProHand generator ...
(Date:6/25/2016)... ... ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter of ... too high can result in disappointment, perhaps even self-loathing. However, those who set the ... Research from PsychTests.com reveals that behind the tendency to set low expectations ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Scientific Sessions in Dallas that it will receive two significant new grants to ... came as PHA marked its 25th anniversary by recognizing patients, medical professionals and ...
(Date:6/24/2016)... TX (PRWEB) , ... June 24, 2016 , ... People ... part in Genome magazine’s Code Talker Award, an essay contest in which patients and ... an award to be presented at the 2016 National Society of Genetic Counselors (NSGC) ...
(Date:6/24/2016)... ... , ... National recruitment firm Slone Partners is pleased to announce ... experience, as Vice President of North American Capital Sales at HTG Molecular . ... sales team in the commercialization of the HTG EdgeSeq system and associated reagents in ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... ANDOVER, Mass. and SAN CLEMENTE, Calif. ... California -based mobile pulmonary function testing company, is now ... portable PFT devices developed by ndd Medical Technologies , Inc. ... PFT testing done in hospital-based labs.  Thanks to ndd,s EasyOne PRO ... CA , can get any needed testing done in the ...
(Date:6/24/2016)... 2016  Arkis BioSciences, a leading innovator in ... durable cerebrospinal fluid treatments, today announced it has ... is led by Innova Memphis, followed by Angel ... investors.  Arkis, new financing will accelerate the commercialization ... release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... 23, 2016  In a startling report released today, National ... by lacking a comprehensive, proven plan to eliminate prescription opioid overdoses. ... of how states are tackling the worst drug crisis in recorded ... – Kentucky , New Mexico ... . Of the 28 failing states, three – Michigan ...
Breaking Medicine Technology: