Navigation Links
Aspirin May Increase Risk of Crohn's Disease
Date:5/3/2010

But experts add that painkiller's other health benefits may outweigh possible link

MONDAY, May 3 (HealthDay News) -- A new British study finds that people who take aspirin every day have a higher risk of developing Crohn's disease, a potentially devastating digestive illness.

But it's still not very likely that aspirin users will develop the condition, and the study's lead author said patients should keep in mind that aspirin lowers the risk of heart disease.

"If the link with aspirin is a true one, then only a small proportion of those who take aspirin -- approximately one in 2,000 -- may be at risk," said study author Dr. Andrew Hart, a senior lecturer in gastroenterology at University of East Anglia School of Medicine. "If aspirin has been prescribed to people with Crohn's disease or with a family history by their physician, then they should continue to take it. Aspirin has many beneficial effects and should be continued."

An estimated 500,000 people in the United States have Crohn's disease, which causes digestive problems and can boost the risk of bowel cancer. In some cases, patients must undergo surgery; many have to take medications for the rest of their lives.

While aspirin is known for its ability to reduce the risk of heart disease, it can cause stomach ulcers, and research in animals has suggested it can be hard on the intestines, too. The study authors decided to see if it had the same effect in humans, Hart said.

In the new study, researchers tracked 200,000 volunteers, aged 30 to 74, from several European countries.

The researchers found that aspirin use for a year or more boosted the risk of Crohn's disease by five times.

However, the study only suggests there's a link between aspirin use and the disease; it doesn't prove that aspirin actually increased the risk. And the researchers didn't know how much aspirin each person took.

Why might aspirin boost the risk of Crohn's disease? Dr. William J. Sandborn, vice chair of Mayo Clinic's Division of Gastroenterology and Hepatology, said it might have something to do with aspirin damaging the lining of the bowel, potentially triggering the condition in those who are susceptible to it because of their genetic makeup.

Sandborn, who's familiar with the findings, agreed with Hart that patients need to think about the benefits of aspirin use, including the reduced risk of not only heart disease but also colorectal cancer.

The study found no link between aspirin use and ulcerative colitis, another digestive disorder.

Future research is needed to confirm the aspirin-Crohn's disease link and determine what aspirin has to do with the higher risk, Hart said.

"If it does turn out to be a true link in the future, then it will be only one of many factors involved in causing Crohn's disease," he said. "Because aspirin has benefits, users should continue with it."

The study was to be presented Monday at the Digestive Disease Week conference in New Orleans.

More information

For more about Crohn's disease, see the U.S. National Library of Medicine.



-- Randy Dotinga



SOURCES: Andrew Hart, M.D, senior lecturer, gastroenterology, University of East Anglia School of Medicine, United Kingdom; William J. Sandborn, M.D., vice chair, division of gastroenterology and hepatology, Mayo Clinic, Rochester, Minn.; May 3, 2010, presentation, Digestive Disease Week conference, New Orleans


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. In Women, Aspirin Might Ward Off Eye Trouble
2. Aspirin During Pregnancy May Help Preemies
3. Three Anticoagulant Studies May Change Current Medical Practice Including New Data Revealing That Preventative Use of Aspirin and Heparin is Not Effective in Reducing Recurrent, Unexplained Miscarriages
4. Aspirin May Boost Breast Cancer Survival
5. Cardiologists Comment on Aspirin Versus Resveratrol
6. Aspirin Alone Works Best to Prevent Clots a Year After Stenting
7. Connecture, Inc. Launches New Technology Package to Increase Health Insurance Carriers' Success in the Online Individual Market
8. Cocaine or ecstasy consumption during adolescence increases risk of addiction
9. New Research Shows Genes of Pregnant Women and Their Fetuses Can Increase the Risk of Preterm Labor
10. Genes of pregnant women and their fetuses can increase the risk of preterm labor
11. NIH scientists identify maternal and fetal genes that increase preterm birth risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2017)... , ... February 26, 2017 , ... NuevaCare, a leading ... diverse as Millbrae, Belmont, and Palo Alto, is proud to announce an important upgrade ... Area consumers look for home care close to home, and by having city-specific pages, ...
(Date:2/26/2017)... ... February 26, 2017 , ... ODH, Inc.™ announced today it ... at the Sheraton Pentagon City Hotel in Arlington, VA. ODH’s director of medical strategy, ... health analytics to improve Medicaid population health management. , ODH will also have an ...
(Date:2/24/2017)... Prior Lake MN (PRWEB) , ... February 24, ... ... the launch of its newly designed TaskMate Go. Core benefits and advantages built ... grain finish and a stylish, functional look and feel. Ability to gain the ...
(Date:2/24/2017)... ... February 24, 2017 , ... An in-depth computational analysis of genetic ... Pittsburgh points to eight genes that may explain why susceptibility to one of the ... of a study published today in the journal npj Schizophrenia. , “There is ...
(Date:2/24/2017)... ... , ... With millions of Americans and people worldwide struggling ... are aware of our options and are empowered with strength and information throughout ... its newest edition of "Vision and Hearing" in USA Today, that will educate ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... 2017  Today, exocad America and the Biodenta ... new path to produce 510(K) cleared, in-house milled, ... integrated into exocad DentalCAD software. In order to ... Manufacturing Processes (GMP,s) into their organization, sign up ... an audit process. Then, dental labs can use Biodenta,s ...
(Date:2/24/2017)... , Feb. 24, 2017 Zimmer Biomet Holdings, ... musculoskeletal healthcare, will present at the Cowen and Company ... Boston Marriott Copley Place on Tuesday, March 7, 2017 ... live webcast of the presentation can be accessed at ... replay following the conference via Zimmer Biomet,s Investor Relations ...
(Date:2/24/2017)... Research and Markets has announced the addition of the "Dry ... offering. ... Dry eye Drugs Price Analysis and Strategies - 2016, provides drug pricing ... answers the following questions: What are the ... they positioned in the Global Dry eye market? What ...
Breaking Medicine Technology: